A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies
Conditions: Acute Myeloid Leukemia; Myelodysplastic Syndromes; Myeloid Malignancies; MDS; Inherited Bone Marrow Failure Syndrome; Myeloid Neoplasm; Aml Interventions: Drug: Decitabine; Drug: Filgrastim Sponsors: Franziska Wachter; Harvard Clinical and Translational Science Center (Harvard Catalyst) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2023 Category: Research Source Type: clinical trials
A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies
Conditions: Acute Leukemia; Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Acute Biphenotypic Leukemia; Acute Undifferentiated Leukemia Interventions: Drug: Busulfan; Drug: Fludarabine; Radiation: Total Body Irradiation; Drug: Cyclophosphamide; Drug: Mesna; Procedure: Bone Marrow Transplant; Drug: Tacrolimus; Drug: Mycophenolate Mofetil; Drug: Filgrastim Sponsors: Ossium Health, Inc.; Center for International Blood and Marrow Transplant Research Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 21, 2022 Category: Research Source Type: clinical trials
