Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
Conditions: Acute Leukemia of Ambiguous Lineage in Relapse; Acute Myeloid Leukemia, in Relapse; Refractory Acute Leukemia of Ambiguous Lineage; Refractory Acute Myeloid Leukemia Interventions: Drug: Venetoclax; Drug: Selinexor; Drug: Cytarabine; Drug: Fludarabine; Biological: Filgrastim; Drug: Methotrexate; Drug: methotrexate/hydrocortisone/cytarabine Sponsors: St. Jude Children's Research Hospital; Karyopharm Therapeutics Inc; AbbVie; Cookies for Kids' Cancer Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2021 Category: Research Source Type: clinical trials
Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
Conditions: Acute Leukemia of Ambiguous Lineage in Relapse; Acute Myeloid Leukemia, in Relapse; Refractory Acute Leukemia of Ambiguous Lineage; Refractory Acute Myeloid Leukemia Interventions: Drug: Venetoclax; Drug: Selinexor; Drug: Cytarabine; Drug: Fludarabine; Biological: Filgrastim; Drug: Methotrexate; Drug: methotrexate/hydrocortisone/cytarabine Sponsors: St. Jude Children's Research Hospital; Karyopharm Therapeutics Inc; AbbVie; Gateway for Cancer Research Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 24, 2021 Category: Research Source Type: clinical trials
A Randomized, Multicenter Pragmatic Trial Comparing Bone Pain From a Single Dose of Pegfilgrastim to 5 Doses of Daily Filgrastim in Breast Cancer Patients Receiving Neoadjuvant/Adjuvant Chemotherapy
Condition: Early-stage Breast Cancer Interventions: Drug: Filgrastim; Drug: Pegfilgrastim Sponsor: Ottawa Hospital Research Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2021 Category: Research Source Type: clinical trials
