Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease
Conditions: Chronic Granulomatous Disease (CGD); X-Linked Chronic Granulomatous Disease Interventions: Biological: Base-edited hematopoietic stem and progenitor cells; Drug: Busulfan; Drug: Palifermin; Drug: Filgrastim; Drug: Plerixafor Sponsors: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Novel Preventive Approach Against Filgrastim-Induced Bone Pain in Cancer Patients
Conditions: Breast Cancer; Filgrastim Adverse Reaction Interventions: Drug: Placebo; Drug: famotidine and loratadine Sponsors: Noha Mansour Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 19, 2024 Category: Research Source Type: clinical trials
Multicenter Study of Safety and Efficacy Nivolumab at the Fixed Dose 40 mg (Nivo40) in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed PMBL
Conditions: Primary Mediastinal Lymphoma Interventions: Drug: Cyclophosphamide; Drug: Doxorubicin Hydrochloride; Drug: Etoposide Phosphate; Drug: Prednisolone; Drug: Rituximab; Drug: Vincristine Sulfate; Drug: Filgrastim; Drug: Pegfilgrastim; Drug: Nivolumab 40 mg in 4 ml Injection Sponsors: National Research Center for Hematology, Russia Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials
The Role of Granulocyte Colony Stimulating Factor in Embryo Transfer Outcomes
Conditions: Infertility; Infertility,Female; Infertility; Female, Nonimplantation; Infertility Unexplained; Infertility of Uterine Origin Interventions: Drug: Granulocyte Colony-Stimulating Factor (Filgrastim); Other: Standard Embryo Transfer Media Sponsors: Newlife Fertility Centre Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 18, 2023 Category: Research Source Type: clinical trials
The Neuroprotective Effect of PEG-GCSF in the Traumatic Optic Neuropathy
Conditions: Traumatic Optic Neuropathy Interventions: Drug: Neulasta ® (pegfilgrastim) Sponsors: Buddhist Tzu Chi General Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials
Continuous Versus Bolus Administration of G-CSF in Children With Cancer
Conditions: Pediatric Cancer; Neutropenia; Lenograstim; Filgrastim; G-CSF Interventions: Device: G-CSF administration (bolus injection versus intravenous infusion); Drug: G-CSF administration (bolus injection versus intravenous infusion) Sponsors: Chang Gung Memorial Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 24, 2023 Category: Research Source Type: clinical trials
Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease
Condition: Rhabdomyosarcoma Interventions: Drug: Vincristine; Drug: Dactinomycin; Drug: Cyclophosphamide; Procedure: Surgical Resection; Procedure: Proton beam radiation or external beam radiation or brachytherapy; Drug: Liposomal irinotecan; Drug: Vinorelbine; Drug: Temozolomide; Drug: Filgrastim, peg- filgrastim Sponsor: St. Jude Children's Research Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials
