Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer
Conditions: Locally Advanced Rectal Cancer Interventions: Drug: capecitabine; Drug: tislelizumab; Drug: thymalfasin; Radiation: long-term radiotherapy Sponsors: Beijing Friendship Hospital; Peking Union Medical College Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials

Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma
Conditions: Esophageal Squamous Cell Carcinoma; Neoadjuvant Chemoimmunotherapy; Adjuvant Therapy Interventions: Drug: Tislelizumab Sponsors: Guo Xufeng Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials

Neoadjuvant of Sintilimab Combined Weekly Metronomic Chemotherapy (PLOF) for Resectable Locally Advanced Gastric Cancer
Condition:   Gastric Cancer Intervention:   Drug: sintilimab+metronomic PLOF Sponsor:   Huashan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 26, 2023 Category: Research Source Type: clinical trials

Neoadjuvant of Sintilimab Combined Weekly Metronomic Chemotherapy (PLOF) for Resectable Locally Advanced Gastric Cancer
Conditions: Gastric Cancer Interventions: Drug: sintilimab+metronomic PLOF Sponsors: Huashan Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 26, 2023 Category: Research Source Type: clinical trials

Efficacy and Safety of SCRT Versus TNT in Older Patients With Locally Advanced Rectal Cancer
Conditions: Locally Advanced Rectal Cancer; Older People Interventions: Radiation: Short course radiotherapy; Drug: Adjuvant chemotherapy (optional); Procedure: Total mesorectal excision; Combination Product: Total neoadjuvant therapy Sponsors: Jules Bordet Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 25, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer
Conditions:   Larynx Cancer;   Hypopharyngeal Cancer Interventions:   Procedure: Surgery;   Radiation: Radiation;   Drug: Toripalimab Sponsors:   Fudan University;   Fudan University Eye Ear Nose and Throat Hospital;   Shanghai Zhongshan Hospital;   Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University;   Ruijin Hospital;   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials

Efficacy and Safety of the Proposed Biosimilar PERT-IJS Versus EU-Perjeta ® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer
Condition:   HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients Interventions:   Biological: PERT-IJS plus trastuzumab, carboplatin and docetaxel;   Biological: Perjeta plus trastuzumab, carboplatin and docetaxel Sponsor:   Biocon Biologics UK Ltd Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer
Conditions:   Larynx Cancer;   Hypopharyngeal Cancer Interventions:   Procedure: Surgery;   Radiation: Radiation;   Drug: Toripalimab Sponsors:   Fudan University;   Fudan University Eye Ear Nose and Throat Hospital;   Shanghai Zhongshan Hospital;   Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University;   Ruijin Hospital;   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials

Efficacy and Safety of the Proposed Biosimilar PERT-IJS Versus EU-Perjeta ® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer
Condition:   HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients Interventions:   Biological: PERT-IJS plus trastuzumab, carboplatin and docetaxel;   Biological: Perjeta plus trastuzumab, carboplatin and docetaxel Sponsor:   Biocon Biologics UK Ltd Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer
Conditions:   Larynx Cancer;   Hypopharyngeal Cancer Interventions:   Procedure: Surgery;   Radiation: Radiation;   Drug: Toripalimab Sponsors:   Fudan University;   Fudan University Eye Ear Nose and Throat Hospital;   Shanghai Zhongshan Hospital;   Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University;   Ruijin Hospital;   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials

Efficacy and Safety of the Proposed Biosimilar PERT-IJS Versus EU-Perjeta ® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer
Condition:   HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients Interventions:   Biological: PERT-IJS plus trastuzumab, carboplatin and docetaxel;   Biological: Perjeta plus trastuzumab, carboplatin and docetaxel Sponsor:   Biocon Biologics UK Ltd Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer
Conditions:   Larynx Cancer;   Hypopharyngeal Cancer Interventions:   Procedure: Surgery;   Radiation: Radiation;   Drug: Toripalimab Sponsors:   Fudan University;   Fudan University Eye Ear Nose and Throat Hospital;   Shanghai Zhongshan Hospital;   Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University;   Ruijin Hospital;   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials

Efficacy and Safety of the Proposed Biosimilar PERT-IJS Versus EU-Perjeta ® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer
Condition:   HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients Interventions:   Biological: PERT-IJS plus trastuzumab, carboplatin and docetaxel;   Biological: Perjeta plus trastuzumab, carboplatin and docetaxel Sponsor:   Biocon Biologics UK Ltd Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials