Irinotecan Liposome for Resectable Pancreatic Cancer With or Without Addebelizumab
Conditions: Neoadjuvant Chemotherapy; Resectable Pancreatic Cancer Interventions: Drug: irinotecan liposome + oxaliplatin + 5-FU / LV; Drug: Adebellizumab Sponsors: Zhejiang University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 15, 2023 Category: Research Source Type: clinical trials

An Observational Study to Evaluate Neoadjuvant Nivolumab (OPDIVO ®) in Combination With Platinum-Based Chemotherapy in Non-Metastatic Non-Small Cell Lung Cancer Participants in Germany
Conditions: Resectable Non-small Cell Lung Cancer Interventions: Drug: Neoadjuvant nivolumab in combination with platinum-based chemotherapy Sponsors: Bristol-Myers Squibb Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

Stereotactic Radiotherapy Combined With Adebrelimab and TCb (Nab-paclitaxel + Carboplatin) in Neoadjuvant Treatment of TNBC
Conditions: Stereotactic Radiotherapy; Immunotherapy; Breast Cancer Interventions: Drug: adebrelimab plus stereotactic radiotherapy followed by adebrelimab plus chemotherapy (nab-paclitaxel + carboplatin); Drug: adebrelimab plus chemotherapy (nab-paclitaxel + carboplatin) Sponsors: Shengjing Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma:A Prospective, Multicenter, Phase II Study
Conditions: Esophageal Squamous Cell Carcinoma; Neoadjuvant Therapies Interventions: Drug: Cardenilimab Combined With Chemotherapy Sponsors: Li Zhang Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 11, 2023 Category: Research Source Type: clinical trials

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma
Conditions: Esophageal Squamous Cell Carcinoma; Neoadjuvant Therapies Interventions: Drug: Cardenilimab Combined With Chemotherapy Sponsors: Li Zhang Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 11, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Trastuzumab, Pertuzumab and Tucatinib Without Chemotherapy in HER2-positive Breast Cancer: the TRAIN-4 Study
Conditions: Breast Cancer Interventions: Drug: Tucatinib; Drug: Trastuzumab; Drug: Pertuzumab Sponsors: The Netherlands Cancer Institute; Seagen Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 8, 2023 Category: Research Source Type: clinical trials

Organoids Based Drug Sensitivity in Neoadjuvant Chemotherapy of Breast Cancer
Conditions: Organoids; Breast Cancer; Neoadjuvant Chemotherapy Interventions: Procedure: Biopsy Sponsors: Second Affiliated Hospital, School of Medicine, Zhejiang University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 4, 2023 Category: Research Source Type: clinical trials

Neoadjuvant PD-1 Inhibitor Combined With Cetuximab and Platinum in Resectable Locally Advanced Hypopharyngeal Carcinoma
Conditions: Locally Advanced Hypopharyngeal Carcinoma Interventions: Drug: three cycles (toripalimab + cetuximab + platinum); Procedure: Radical surgery; Radiation: Radiotherapy or chemoradiotherapy Sponsors: Eye& ENT Hospital of Fudan University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 30, 2023 Category: Research Source Type: clinical trials

Muscle Parameters and Pathological Response in Breast Cancer Patients
Conditions: Neoadjuvant Chemotherapy Interventions: Other: Neoadjuvant therapy Sponsors: Ac ıbadem Atunizade Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 30, 2023 Category: Research Source Type: clinical trials

Micrometastases in Axillary Lymph Nodes in Breast Cancer, Post-neoadjuvant Chemotherapy
Conditions: Micrometastases; Neoadjuvant Chemotherapy Interventions: Procedure: Sentinel lymph node biopsy, axillary lymph node dissection Sponsors: Gangnam Severance Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 29, 2023 Category: Research Source Type: clinical trials

Response to Neoadjuvant Chemoimmunotherapy in Resectable Locally Advanced Oral Cancer
Conditions: Oral Cancer Interventions: Drug: PD-1 inhibitor+carboplatin+albumin-bound paclitaxel Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials

Neoadjuvant Pyrotinib Versus Placebo Combined With Chemotherapy in HR-positive and HER2-low Early Breast Cancer
Conditions: Breast Cancer Invasive; Hormone-receptor-positive Breast Cancer; HER2 Low Breast Carcinoma; Early-stage Breast Cancer Interventions: Drug: Pyrotinib, epirubicin or doxorubicin, cyclophosphamide, paclitaxel; Drug: Placebo, epirubicin or doxorubicin, cyclophosphamide, paclitaxel Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; Jiangsu HengRui Medicine Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials

PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy
Conditions: Locally Advanced Pancreatic Adenocarcinoma; Stage III Pancreatic Cancer American Joint Committee on Cancer v8; Unresectable Pancreatic Adenocarcinoma Interventions: Procedure: Biospecimen Collection; Procedure: Computed Tomography; Procedure: Distal Pancreatectomy; Procedure: Laparoscopy; Procedure: Magnetic Resonance Imaging; Procedure: Pancreaticoduodenectomy; Other: Questionnaire Administration; Procedure: Surgical Procedure; Procedure: Total Pancreatectomy Sponsors: University of Southern California; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2023 Category: Research Source Type: clinical trials

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Initially Node Positive Breast Cancer Patients, Could it Omit Axillary Dissection ?
Conditions: Sentinel Lymph Node Interventions: Procedure: sentinle lymphnode biopsy Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 14, 2023 Category: Research Source Type: clinical trials

Conserving Surgery in Inflammatory Breast Cancer After Neoadjuvant Chemotherapy
Conditions: Inflammatory Breast Cancer Interventions: Procedure: Breast conserving surgery; Procedure: Radical modified mastectomy Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 14, 2023 Category: Research Source Type: clinical trials