Indication and Surgical Procedures for MEN1-associated Duodenopancreatic Neuroendocrine Neoplasms
Zentralbl Chir. 2023 Aug 21. doi: 10.1055/a-2103-3525. Online ahead of print.ABSTRACTThe optimal therapy of duodenopancreatic neuroendocrine neoplasia (dpNEN), which occurs in the context of multiple endocrine neoplasia type 1, is still a major challenge and is controversial. Due to the rarity of the disease, there is a lack of prospective randomised studies, so that most recommendations regarding the surgical indication and procedure are based on retrospective case series. In summary, surgical therapy is indicated for non-functional dpNEN > 2 cm, suspected malignancy and functionally active dpNEN. Enucleation or formal...
Source: Zentralblatt fur Chirurgie - August 21, 2023 Category: Surgery Authors: Jerena Manoharan Max Albers Detlef K Bartsch Source Type: research

Indication and Surgical Procedures for MEN1-associated Duodenopancreatic Neuroendocrine Neoplasms
Zentralbl Chir. 2023 Aug 21. doi: 10.1055/a-2103-3525. Online ahead of print.ABSTRACTThe optimal therapy of duodenopancreatic neuroendocrine neoplasia (dpNEN), which occurs in the context of multiple endocrine neoplasia type 1, is still a major challenge and is controversial. Due to the rarity of the disease, there is a lack of prospective randomised studies, so that most recommendations regarding the surgical indication and procedure are based on retrospective case series. In summary, surgical therapy is indicated for non-functional dpNEN > 2 cm, suspected malignancy and functionally active dpNEN. Enucleation or formal...
Source: Zentralblatt fur Chirurgie - August 21, 2023 Category: Surgery Authors: Jerena Manoharan Max Albers Detlef K Bartsch Source Type: research

Indication and Surgical Procedures for MEN1-associated Duodenopancreatic Neuroendocrine Neoplasms
Zentralbl Chir. 2023 Aug 21. doi: 10.1055/a-2103-3525. Online ahead of print.ABSTRACTThe optimal therapy of duodenopancreatic neuroendocrine neoplasia (dpNEN), which occurs in the context of multiple endocrine neoplasia type 1, is still a major challenge and is controversial. Due to the rarity of the disease, there is a lack of prospective randomised studies, so that most recommendations regarding the surgical indication and procedure are based on retrospective case series. In summary, surgical therapy is indicated for non-functional dpNEN > 2 cm, suspected malignancy and functionally active dpNEN. Enucleation or formal...
Source: Zentralblatt fur Chirurgie - August 21, 2023 Category: Surgery Authors: Jerena Manoharan Max Albers Detlef K Bartsch Source Type: research

Indication and Surgical Procedures for MEN1-associated Duodenopancreatic Neuroendocrine Neoplasms
Zentralbl Chir. 2023 Aug 21. doi: 10.1055/a-2103-3525. Online ahead of print.ABSTRACTThe optimal therapy of duodenopancreatic neuroendocrine neoplasia (dpNEN), which occurs in the context of multiple endocrine neoplasia type 1, is still a major challenge and is controversial. Due to the rarity of the disease, there is a lack of prospective randomised studies, so that most recommendations regarding the surgical indication and procedure are based on retrospective case series. In summary, surgical therapy is indicated for non-functional dpNEN > 2 cm, suspected malignancy and functionally active dpNEN. Enucleation or formal...
Source: Zentralblatt fur Chirurgie - August 21, 2023 Category: Surgery Authors: Jerena Manoharan Max Albers Detlef K Bartsch Source Type: research

Indication and Surgical Procedures for MEN1-associated Duodenopancreatic Neuroendocrine Neoplasms
Zentralbl Chir. 2023 Aug 21. doi: 10.1055/a-2103-3525. Online ahead of print.ABSTRACTThe optimal therapy of duodenopancreatic neuroendocrine neoplasia (dpNEN), which occurs in the context of multiple endocrine neoplasia type 1, is still a major challenge and is controversial. Due to the rarity of the disease, there is a lack of prospective randomised studies, so that most recommendations regarding the surgical indication and procedure are based on retrospective case series. In summary, surgical therapy is indicated for non-functional dpNEN > 2 cm, suspected malignancy and functionally active dpNEN. Enucleation or formal...
Source: Zentralblatt fur Chirurgie - August 21, 2023 Category: Surgery Authors: Jerena Manoharan Max Albers Detlef K Bartsch Source Type: research

Indication and Surgical Procedures for MEN1-associated Duodenopancreatic Neuroendocrine Neoplasms
Zentralbl Chir. 2023 Aug 21. doi: 10.1055/a-2103-3525. Online ahead of print.ABSTRACTThe optimal therapy of duodenopancreatic neuroendocrine neoplasia (dpNEN), which occurs in the context of multiple endocrine neoplasia type 1, is still a major challenge and is controversial. Due to the rarity of the disease, there is a lack of prospective randomised studies, so that most recommendations regarding the surgical indication and procedure are based on retrospective case series. In summary, surgical therapy is indicated for non-functional dpNEN > 2 cm, suspected malignancy and functionally active dpNEN. Enucleation or formal...
Source: Zentralblatt fur Chirurgie - August 21, 2023 Category: Surgery Authors: Jerena Manoharan Max Albers Detlef K Bartsch Source Type: research