Multidrug Resistance Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)-producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial
DiscussionAs the use of probiotics may give a more favorable gut composition, and thereby improve health and reduce morbidity and mortality, the results may have implications for future therapy guidelines in Africa and internationally.Trial registrationClinicalTrials.gov NCT04172012. Registered on November 21, 2019 (Source: Trials)
Source: Trials - April 29, 2021 Category: Research Source Type: clinical trials

Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales ( “MERINO-3”): study protocol for a multicentre, open-label randomised non-inferiority trial
This study will use a multicentre, parallel group open-label non-inferiority trial design comparing ceftolozane-tazobactam and meropenem in adult patients with bloodstream infection caused by ESBL or AmpC-producing Enterobacterales. Trial recruitment will occur in up to 40 sites in six countries (Australia, Singapore, Italy, Spain, Saudi Arabia and Lebanon). The sample size is determined by a predefined quantity of ceftolozane-tazobactam to be supplied by Merck, Sharpe and Dohme (MSD). We anticipate that a trial with 600 patients contributing to the primary outcome analysis would have 80% power to declare non-inferiority w...
Source: Trials - April 22, 2021 Category: Research Source Type: clinical trials

Multidrug Resistant Gram-negative Pathogen Infections in High Risk Neonates in the Northeast of Mexico
Condition: Infant Newborn Disease Intervention: Diagnostic Test: Identification of MDR characteristics Sponsor: Instituto Tecnologico y de Estudios Superiores de Monterey Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 24, 2021 Category: Research Source Type: clinical trials