Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research
Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research
Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research
Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research
Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research
Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research
Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research
Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research
Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research
Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research
Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research
Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research
Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research
Viable Leishmania parasites in the absence of an in vitro IFN- γ response in asymptomatic carriers
This study aimed to identify the in vitro expression of IFN-γ in asymptomatic carriers of viable Leishmania parasites. Asymptomatic infection was identified using the Montenegro skin test in an at-risk population from Yucatan, Mexico. Parasite viability was evinced in the blood by 7SL RNA transcripts amplification. The expression of mRNA IFN-γ was analyzed in peripheral blood mononuclear cells stimulated with soluble Leishmania antigen, using RT-qPCR. Parasite viability was observed in 33.3 % (5/15) of asymptomatic subjects. No differences were found in the expression of IFN-γ between asymptomatic and healthy subjects, ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 21, 2024 Category: Tropical Medicine Authors: Elsy Nalleli Lor ía-Cervera Erika Ivett Sosa-Bibiano Karina Beatriz L ópez-Ávila Ana Celia Montes de Oca-Aguilar Marisol Sarah í Moreno-Nava Jimmy Raymundo Torres-Castro Source Type: research
Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research
