Differences in DNA methylation status explain phenotypic variability in patients with 5p − syndrome
Cri Du Chat syndrome, or 5p − syndrome, is characterized by a terminal or interstitial deletion on the short arm of chromosome 5 that causes variable clinical manifestations, including high-pitched cry in newbo... (Source: BMC Research Notes)
Source: BMC Research Notes - April 29, 2024 Category: Research Authors: Vanessa Tavares Almeida, Samar N. Chehimi, Gleyson F. S. Carvalho, Yanca Gasparini, Amom M. Nascimento, Lucas L. Vieira, Beatriz M. Wolff, Mar ília M. Montenegro and Leslie D. Kulikowski Tags: Research Note Source Type: research
SEEIIST – a new research facility for tumor treatment and biomedical investigations with proton and ion beams
ConclusionsThis infrastructure is unique for Europe and will attract researchers from all European countries to perform their investigations. (Source: Health and Technology)
Source: Health and Technology - April 23, 2024 Category: Information Technology Source Type: research
Predictors of genetic diagnosis in individuals with developmental and epileptic encephalopathies
CONCLUSION: The predictive variables of genetic investigation in developmental and epileptic encephalopathies are first seizure in the context of fever and hypotonia, whereas atonic seizures decrease the chances of finding a genetic cause for developmental and epileptic encephalopathies. Regarding epileptic syndromes, Dravet Syndrome is highly associated with a positive genetic test, whereas epilepsy with myoclonic-atonic seizures, developmental and epileptic encephalopathies with spike-wave activation in sleep, and Lennox-Gastaut syndrome are rarely associated with a positive genetic investigation.PMID:38636144 | DOI:10.1...
Source: Epilepsy and Behaviour - April 18, 2024 Category: Neurology Authors: Maria Luiza Benevides Helena T de Moraes Diana M M Granados Luciana C Bonadia Let ícia Sauma Maria Augusta Montenegro Marilisa M Guerreiro Íscia Lopes-Cendes Ana Carolina Coan Source Type: research
Incorporation, adaptation and rejection of obstetric practices during the implementation of the “Adequate Childbirth Program” in Brazilian private hospitals: a qualitative study
This study aimed to analyze labor and... (Source: Reproductive Health)
Source: Reproductive Health - April 17, 2024 Category: OBGYN Authors: D ébora Cecília Chaves de Oliveira, Maysa Luduvice Gomes, Andreza Rodrigues, Thamires Soares, Lucia Regina de Azevedo Nicida, Jacqueline Alves Torres and Elyne Montenegro Engstrom Tags: Research Source Type: research
Changes in bone mineral density in patients with non-dialysis dependent chronic kidney disease are associated with body composition.
Chronic kidney disease (CKD) and low bone mineral density (BMD) are highly prevalent and can co-exist. Parameters of mineral metabolism are associated with BMD in CKD, but other contributing factors may contribute. The aim of this study was to assess changes in BMD and its determinants in patients with non-dialysis-dependent CKD (NDD-CKD). (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 13, 2024 Category: Urology & Nephrology Authors: Julia Montenegro, M árcia Regina Simas Torres Klein, Carla M. Prado, Maria Inês Barreto Silva Tags: Original Research Source Type: research
Development and evaluation of a single-tube nested PCR with colorimetric assay for < em > Mycobacterium tuberculosis < /em > detection
Biotechniques. 2024 Apr 11. doi: 10.2144/btn-2023-0080. Online ahead of print.ABSTRACTMolecular techniques have revolutionized tuberculosis (TB) diagnosis by offering a faster and more sensitive approach, detecting Mycobacterium tuberculosis (Mtb) DNA directly from samples. Single-tube nested PCR (STNPCR) combines two PCR reactions with separate oligonucleotide sets in a single tube. Moreover, colorimetric methods in PCR products have been studied for pathogen detection. Thus, this study aimed to establish a novel system based on colorimetric STNPCR for Mtb detection using microtiter plates with IS6110-amplified fragments....
Source: BioTechniques - April 11, 2024 Category: Biotechnology Authors: Marcela Pereira Salazar Juliana Figueiredo da Costa Lima Suassuna Monteiro Wlisses Henrique Veloso Carvalho-Silva George Tadeu Nunes Diniz Roberto Pereira Werkhauser L ílian Maria Lapa Montenegro Haiana Charifker Schindler Source Type: research
Development and evaluation of a single-tube nested PCR with colorimetric assay for < em > Mycobacterium tuberculosis < /em > detection
Biotechniques. 2024 Apr 11. doi: 10.2144/btn-2023-0080. Online ahead of print.ABSTRACTMolecular techniques have revolutionized tuberculosis (TB) diagnosis by offering a faster and more sensitive approach, detecting Mycobacterium tuberculosis (Mtb) DNA directly from samples. Single-tube nested PCR (STNPCR) combines two PCR reactions with separate oligonucleotide sets in a single tube. Moreover, colorimetric methods in PCR products have been studied for pathogen detection. Thus, this study aimed to establish a novel system based on colorimetric STNPCR for Mtb detection using microtiter plates with IS6110-amplified fragments....
Source: BioTechniques - April 11, 2024 Category: Biotechnology Authors: Marcela Pereira Salazar Juliana Figueiredo da Costa Lima Suassuna Monteiro Wlisses Henrique Veloso Carvalho-Silva George Tadeu Nunes Diniz Roberto Pereira Werkhauser L ílian Maria Lapa Montenegro Haiana Charifker Schindler Source Type: research
Development and evaluation of a single-tube nested PCR with colorimetric assay for < em > Mycobacterium tuberculosis < /em > detection
Biotechniques. 2024 Apr 11. doi: 10.2144/btn-2023-0080. Online ahead of print.ABSTRACTMolecular techniques have revolutionized tuberculosis (TB) diagnosis by offering a faster and more sensitive approach, detecting Mycobacterium tuberculosis (Mtb) DNA directly from samples. Single-tube nested PCR (STNPCR) combines two PCR reactions with separate oligonucleotide sets in a single tube. Moreover, colorimetric methods in PCR products have been studied for pathogen detection. Thus, this study aimed to establish a novel system based on colorimetric STNPCR for Mtb detection using microtiter plates with IS6110-amplified fragments....
Source: BioTechniques - April 11, 2024 Category: Biotechnology Authors: Marcela Pereira Salazar Juliana Figueiredo da Costa Lima Suassuna Monteiro Wlisses Henrique Veloso Carvalho-Silva George Tadeu Nunes Diniz Roberto Pereira Werkhauser L ílian Maria Lapa Montenegro Haiana Charifker Schindler Source Type: research
Development and evaluation of a single-tube nested PCR with colorimetric assay for < em > Mycobacterium tuberculosis < /em > detection
Biotechniques. 2024 Apr 11. doi: 10.2144/btn-2023-0080. Online ahead of print.ABSTRACTMolecular techniques have revolutionized tuberculosis (TB) diagnosis by offering a faster and more sensitive approach, detecting Mycobacterium tuberculosis (Mtb) DNA directly from samples. Single-tube nested PCR (STNPCR) combines two PCR reactions with separate oligonucleotide sets in a single tube. Moreover, colorimetric methods in PCR products have been studied for pathogen detection. Thus, this study aimed to establish a novel system based on colorimetric STNPCR for Mtb detection using microtiter plates with IS6110-amplified fragments....
Source: BioTechniques - April 11, 2024 Category: Biotechnology Authors: Marcela Pereira Salazar Juliana Figueiredo da Costa Lima Suassuna Monteiro Wlisses Henrique Veloso Carvalho-Silva George Tadeu Nunes Diniz Roberto Pereira Werkhauser L ílian Maria Lapa Montenegro Haiana Charifker Schindler Source Type: research
Development and evaluation of a single-tube nested PCR with colorimetric assay for < em > Mycobacterium tuberculosis < /em > detection
Biotechniques. 2024 Apr 11. doi: 10.2144/btn-2023-0080. Online ahead of print.ABSTRACTMolecular techniques have revolutionized tuberculosis (TB) diagnosis by offering a faster and more sensitive approach, detecting Mycobacterium tuberculosis (Mtb) DNA directly from samples. Single-tube nested PCR (STNPCR) combines two PCR reactions with separate oligonucleotide sets in a single tube. Moreover, colorimetric methods in PCR products have been studied for pathogen detection. Thus, this study aimed to establish a novel system based on colorimetric STNPCR for Mtb detection using microtiter plates with IS6110-amplified fragments....
Source: BioTechniques - April 11, 2024 Category: Biotechnology Authors: Marcela Pereira Salazar Juliana Figueiredo da Costa Lima Suassuna Monteiro Wlisses Henrique Veloso Carvalho-Silva George Tadeu Nunes Diniz Roberto Pereira Werkhauser L ílian Maria Lapa Montenegro Haiana Charifker Schindler Source Type: research
Development and evaluation of a single-tube nested PCR with colorimetric assay for < em > Mycobacterium tuberculosis < /em > detection
Biotechniques. 2024 Apr 11. doi: 10.2144/btn-2023-0080. Online ahead of print.ABSTRACTMolecular techniques have revolutionized tuberculosis (TB) diagnosis by offering a faster and more sensitive approach, detecting Mycobacterium tuberculosis (Mtb) DNA directly from samples. Single-tube nested PCR (STNPCR) combines two PCR reactions with separate oligonucleotide sets in a single tube. Moreover, colorimetric methods in PCR products have been studied for pathogen detection. Thus, this study aimed to establish a novel system based on colorimetric STNPCR for Mtb detection using microtiter plates with IS6110-amplified fragments....
Source: BioTechniques - April 11, 2024 Category: Biotechnology Authors: Marcela Pereira Salazar Juliana Figueiredo da Costa Lima Suassuna Monteiro Wlisses Henrique Veloso Carvalho-Silva George Tadeu Nunes Diniz Roberto Pereira Werkhauser L ílian Maria Lapa Montenegro Haiana Charifker Schindler Source Type: research
Development and evaluation of a single-tube nested PCR with colorimetric assay for < em > Mycobacterium tuberculosis < /em > detection
Biotechniques. 2024 Apr 11. doi: 10.2144/btn-2023-0080. Online ahead of print.ABSTRACTMolecular techniques have revolutionized tuberculosis (TB) diagnosis by offering a faster and more sensitive approach, detecting Mycobacterium tuberculosis (Mtb) DNA directly from samples. Single-tube nested PCR (STNPCR) combines two PCR reactions with separate oligonucleotide sets in a single tube. Moreover, colorimetric methods in PCR products have been studied for pathogen detection. Thus, this study aimed to establish a novel system based on colorimetric STNPCR for Mtb detection using microtiter plates with IS6110-amplified fragments....
Source: BioTechniques - April 11, 2024 Category: Biotechnology Authors: Marcela Pereira Salazar Juliana Figueiredo da Costa Lima Suassuna Monteiro Wlisses Henrique Veloso Carvalho-Silva George Tadeu Nunes Diniz Roberto Pereira Werkhauser L ílian Maria Lapa Montenegro Haiana Charifker Schindler Source Type: research
Selective transition enhancement in a g-engineered diradical
This study introduces a methodology to synthesize and characterize g-asymmetric two-spin systems, of interest in the implementation of spin-based CNOT gates.PMID:38563635 | DOI:10.1002/chem.202400420 (Source: Chemistry)
Source: Chemistry - April 2, 2024 Category: Chemistry Authors: Joe Komeda Athanassios Boudalis Nicolas Montenegro-Pohlhammer Cyril Antheaume Asato Mizuno Philippe Turek Mario Ruben Source Type: research
Selective transition enhancement in a g-engineered diradical
This study introduces a methodology to synthesize and characterize g-asymmetric two-spin systems, of interest in the implementation of spin-based CNOT gates.PMID:38563635 | DOI:10.1002/chem.202400420 (Source: Chemistry)
Source: Chemistry - April 2, 2024 Category: Chemistry Authors: Joe Komeda Athanassios Boudalis Nicolas Montenegro-Pohlhammer Cyril Antheaume Asato Mizuno Philippe Turek Mario Ruben Source Type: research
