The effect of selenium supplementation on oxidative stress, clinical symptoms and mental health status in patients with migraine: a study protocol for a double-blinded randomized clinical trial
DiscussionOxidative stress is recognized as a key contributor to migraine pathogenesis. Selenium is an essential trace element with antioxidant properties, capable of crossing the blood –brain barrier (BBB), holding promise to alleviate the oxidative stress and neurotoxicity. Thus, selenium may beneficially affect clinical symptoms and oxidative stress as well as the quality of life in migraine patients.Trial registrationThis trial was registered in the Iranian Registry of Clinical Trials (https://www.irct.ir/) on 27 May 2023 with the code number IRCT20121216011763N60. (Source: Trials)
Source: Trials - March 22, 2024 Category: Research Source Type: clinical trials
Signs of Central Sensitization in Tension-type Headache
Conditions: Tension-Type Headache Interventions: Other: Quantitative Sensory Testing Sponsors: University Ghent Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials
Influence of Role-expectancy on Patient Reported Outcomes Among Patients With Migraine: a Randomized Clinical Trial
Conditions: Role-expectancy on Patient Reported Outcomes Interventions: Behavioral: cover story Sponsors: Universit ätsklinikum Hamburg-Eppendorf Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials
Ultrasound-guided Stellate Ganglion Block for Treatment of Chronic Migraine in Adult
Conditions: Chronic Migraine Interventions: Procedure: Stellate Ganglion Block (SGB); Drug: standardized drug treatment Sponsors: Beijing Tiantan Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials
A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments
Conditions: Migraine Interventions: Drug: Lu AG09222; Drug: Placebo Sponsors: H. Lundbeck A/S Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials
Sphenopalatine Ganglion Block and Cold Induced Headaches
Conditions: Cold Induced Headache; Brain Freeze; Cold Induced Cephalgia; Headache Interventions: Drug: Lidocaine Topical 4% Topical Solution; Drug: Bitrex; Drug: normal saline Sponsors: Wright State University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials
Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients
Conditions: Drug Resistant Epilepsy; Autism Spectrum Disorder; Chronic Migraine; Brain Tumor, Pediatric Interventions: Other: ketogenic diet (as per clinical practice) Sponsors: Danone Nutricia SpA Societ à Benefit Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
The Link Between Human Cytomegalovirus Gene Expression and Glutamate Level in Migraine;Relation to Vitamin D Deficiency
Conditions: Migraine Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Manageable Environmental Factors in Migraine
Conditions: Migraine Interventions: Other: no intervention Sponsors: Samsun University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Impact of COVID-19 Pandemic on Headache Evaluations in the Pediatric Emergency Department
Conditions: COVID-19; Headache Disorders; Emergency Service, Hospital Sponsors: Fondazione IRCCS Ca ' Granda, Ospedale Maggiore Policlinico Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials
nVNS for the Prevention and Treatment of Primary Headache
Conditions: Primary Headache; Migraine in Adolescence; Migraine in Children; Cluster Headache; Tension Headache Interventions: Device: Transcutaneous auricular vagus nerve stimulation Sponsors: Nanfang Hospital, Southern Medical University; BrainClos Co., LTD.; Zhuhai Fudan Innovation Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
Phase I Clinical Trial of Zolmitriptan Transdermal Microporation System Initiated for the Treatment of Acute Migraine
SAN DIEGO, Feb. 23, 2024. PassPort Technologies, Inc. (PPTI), based in San Diego, initiated a US Phase 1 clinical study of Zolmitriptan PassPort utilizing its proprietary transdermal microporation system, PassPort platform technology. The... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 23, 2024 Category: Pharmaceuticals Source Type: clinical trials
Serum Magnesium Level and Pediatric Migraine
Conditions: Migraine, Magnesium, Pediatric Sponsors: Mersin University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials
Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section.
Conditions: Post-Dural Puncture Headache Interventions: Drug: Aminophylline , magnesium sulphate and placebo Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2024 Category: Research Source Type: clinical trials
Pregabalin in Treatment of Postdural Puncture Headache
Conditions: Postdural Puncture Headache Interventions: Drug: Pregabalin 75mg; Biological: An epidural blood patch (EBP); Combination Product: conservative treatment. Sponsors: Al-Azhar University; Benha University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2024 Category: Research Source Type: clinical trials
