Assessment of Methadone and Buprenorphine in Interstitial Fluid
Condition: Opioid Use Disorder Intervention: Procedure: Microneedle based interstitial fluid collection Sponsors: Cari Health Inc.; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 19, 2022 Category: Research Source Type: clinical trials
Extended-release pharmacotherapy for opioid use disorder (EXPO): protocol for an open-label randomised controlled trial of the effectiveness and cost-effectiveness of injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone
This study will determine (A) the effectiveness and cost-effectiveness — monthly injectable, extended-release (BUP-XR) in a head-to-head comparison with BUP-SL and MET, and (B) the effectiveness of BUP-XR with adjunctive PSI versus BUP-SL and MET with PSI. Safety, retention, craving, substance use, quality-adjusted life years, social functioning, and subjective recov ery from OUD will be also evaluated.MethodsThis is a pragmatic, multi-centre, open-label, parallel-group, superiority RCT, with a qualitative (mixed-methods) evaluation. The study population is adults. The setting is five National Health Service community tr...
Source: Trials - August 19, 2022 Category: Research Source Type: clinical trials
Pharmacokinetic Modeling of Methadone
Condition: Toxicomania Intervention: Biological: Blood sampling Sponsor: University Hospital, Montpellier Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 8, 2022 Category: Research Source Type: clinical trials
