A Report from the 2nd Scripps Symposium on the Biology of Aging
This open access paper reports on the proceedings at the 2nd Scripps Symposium on the Biology of Aging held earlier this year. Like much of the field now, the focus in unabashedly on intervening in the aging process, which is good to see. Also like much of the field there is still considerable reluctance to talk in public about the potential for rejuvenation and radical life extension, however, rather than aiming at more modest gains. Still, the core message that we should treat aging as a medical condition has now spread far beyond the small groups that started this advocacy. One of the seven SENS rejuvenation research pr...
Source: Fight Aging! - June 9, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, June 5th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
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Source: Fight Aging! - June 4, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
An Interview with James Peyer of Apollo Ventures
Apollo Ventures is one of the more recent additions to the presently small number of funds focused on investment in the longevity science space, and here I'll point out an interview with one of their founding partners. The Apollo principals are distinguished by being somewhat more vocal than most of their peers, the Methuselah Fund founders aside. To pick one example, the fund has launched the Geroscience online magazine to help advance the position that treating aging as a medical condition is both viable and desirable. As technologies based on the SENS view of achieving rejuvenation through damage repair arrive at the po...
Source: Fight Aging! - May 29, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, May 29th 2017
In this study, we utilized an imaging-based assay to monitor the ability of disease-associated amyloid assemblies to rupture intracellular vesicles following endocytosis. We observe that the ability to induce vesicle rupture is a common feature of α-synuclein (α-syn) assemblies, as assemblies derived from wild type (WT) or familial disease-associated mutant α-syn all exhibited the ability to induce vesicle rupture. Similarly, different conformational strains of WT α-syn assemblies, but not monomeric or oligomeric forms, efficiently induced vesicle rupture following endocytosis.
The ability to induce vesicle rupt...
Source: Fight Aging! - May 28, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Problem with Focusing on Healthspan
There are numerous ways to go about advocacy for the cause of treating aging as medical condition, for the production of therapies to address the aging process. One might focus on talking about extended health, or the goal of greatly increased longevity, or the details of aging as a novel target for medicine, or discard aging as a topic in favor of the development of cures for common, well-recognized age-related diseases - something that can only be achieved through addressing the causes of aging, but many people are more receptive to treating age-related disease rather than treating aging, no matter that these must be one...
Source: Fight Aging! - May 26, 2017 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs
