FDA official: “clinical trial system is broken” - BMJ
FDA investigator Thomas Marciniak has spoken out over drug companies and missing or “bad” data, most famously over rosiglitazone. He tells Deborah Cohenhow he believes the current research and development process is brokenThe clinical trial system is broken and it’s getting worse, according to longstanding Food and Drug Administration investigator, Thomas Marciniak.For seasoned observers of the drug approval process, Marciniak will be a familiar name and his comments will come as little surprise. In his 11 years at the US federal agency, Marciniak has been embroiled in high profile controversies that have pitted...
Source: PharmaGossip - December 9, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs
Yet Another Blow To Combination Renin-Angiotensin-Aldosterone System Blockade
ACE inhibitors and angiotensin-receptor blockers have been found to effectively slow progression of kidney disease. It has been theorized that dual blockade of the renin-angiotensin-aldosterone system (RAAS) might prove even more beneficial, but these hopes have not been realized. Now a new trial published in the New England Journal of Medicine throws further cold water on the once-promising hypothesis. In the Veterans Affairs Nephropathy in Diabetes (VA NEPHRON-D) trial, Linda Fried and colleagues randomized type 2 diabetics with proteinuric kidney disease already receiving the angiotensin-receptor blocker losartan ...
Source: CardioBrief - November 9, 2013 Category: Cardiology Authors: Larry Husten Tags: Policy & Ethics Prevention, Epidemiology & Outcomes ace inhibitor Acute kidney injury ARB chronic kidney disease Renal function Source Type: blogs
Cardiology MCQ Online 3
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You are welcome to try this MCQ set and share it among your friends. Answer key with explanation appears after you complete the test and submit it and press on the view questions button. We strongly advise you t...
Source: Cardiophile MD - July 14, 2013 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Cardiology MCQ Test 3
Cardiology MCQ Online 3
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You are welcome to try this MCQ set and share it among your friends. Answer key with explanation appears after you complete the test and submit it and press on the view questions button. W...
Source: Cardiophile MD - July 14, 2013 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Cardiology Online Test Series 2
Cardiology Online Test Series 2
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You are welcome to try this Cardiology MCQ set and share it among your friends. We strongly advise you to verify the answe...
Source: Cardiophile MD - May 22, 2013 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Cardiology Online Test Series 2
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You are welcome to try this Cardiology MCQ set and share it among your friends. We strongly advise you to verify the answers with standard text books.
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Source: Cardiophile MD - May 21, 2013 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs
Progress report
It's now been three and a half years since I was diagnosed with Chronic Kidney Disease (CKD) and began my quest to cure myself. Although I have not achieved the dramatic recovery I was hoping for my condition appears to be generally stable and this can be considered an acheivement given that the tendency for CKD patients is to gradually lose kidney function until replacement or death becomes necessary. Here are my findings and tips to date so that others may benefit from them (none of which should be construed as medical advice!):
Comments on this blogThanks to all the people who've taken the time to comment on th...
Source: All Kidney News - June 26, 2012 Category: Urology & Nephrology Authors: admin Tags: Uncategorized Source Type: blogs
