A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition:   Malignant Melanoma, NeoplasmsInterventions:   Drug: ketoconazole;   Drug: vemurafenibSponsor:   Hoffmann-La RocheWithdrawn - verified January 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials

A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition:   Malignant Melanoma, NeoplasmsInterventions:   Drug: ketoconazole;   Drug: vemurafenibSponsor:   Hoffmann-La RocheWithdrawn - verified September 2014 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials

A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition:   Malignant Melanoma, NeoplasmsInterventions:   Drug: ketoconazole;   Drug: vemurafenibSponsor:   Hoffmann-La RocheWithdrawn - verified February 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials

A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition:   Malignant Melanoma, NeoplasmsInterventions:   Drug: ketoconazole;   Drug: vemurafenibSponsor:   Hoffmann-La RocheWithdrawn - verified May 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials

A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition:   Malignant Melanoma, NeoplasmsInterventions:   Drug: ketoconazole;   Drug: vemurafenibSponsor:   Hoffmann-La RocheWithdrawn - verified February 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials

A Phase 1 Open-Label Study to Evaluate the Effect of CYP450 and P-gp Inhibition and Induction on the Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects
Conditions:   Pharmacology, Clinical;   HealthyInterventions:   Drug: Pomalidomide;   Drug: Ketoconazole;   Drug: Fluvoxamine;   Drug: CarbamazepineSponsors:   Celgene Corporation;   Celgene CorporationCompleted - verified November 2012 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2012 Category: Research Source Type: clinical trials

Investigation of Drug-drug Interaction of Nintedanib and Ketoconazole in Healthy Male Volunteers
Condition:   HealthyInterventions:   Drug: Nintedanib;   Drug: Nintedanib;   Drug: Ketoconazole;   Drug: Nintedanib;   Drug: Nintedanib;   Drug: KetoconazoleSponsor:   Boehringer IngelheimCompleted - verified November 2014 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 3, 2012 Category: Research Source Type: clinical trials