A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition: Malignant Melanoma, NeoplasmsInterventions: Drug: ketoconazole; Drug: vemurafenibSponsor: Hoffmann-La RocheWithdrawn - verified January 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials
A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition: Malignant Melanoma, NeoplasmsInterventions: Drug: ketoconazole; Drug: vemurafenibSponsor: Hoffmann-La RocheWithdrawn - verified September 2014 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials
A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition: Malignant Melanoma, NeoplasmsInterventions: Drug: ketoconazole; Drug: vemurafenibSponsor: Hoffmann-La RocheWithdrawn - verified February 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials
A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition: Malignant Melanoma, NeoplasmsInterventions: Drug: ketoconazole; Drug: vemurafenibSponsor: Hoffmann-La RocheWithdrawn - verified May 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials
A Pharmacokinetics Study to Investigate the Effect of Ketoconazole on Vemurafenib in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Condition: Malignant Melanoma, NeoplasmsInterventions: Drug: ketoconazole; Drug: vemurafenibSponsor: Hoffmann-La RocheWithdrawn - verified February 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2013 Category: Research Source Type: clinical trials
A Phase 1 Open-Label Study to Evaluate the Effect of CYP450 and P-gp Inhibition and Induction on the Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects
Conditions: Pharmacology, Clinical; HealthyInterventions: Drug: Pomalidomide; Drug: Ketoconazole; Drug: Fluvoxamine; Drug: CarbamazepineSponsors: Celgene Corporation; Celgene CorporationCompleted - verified November 2012 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2012 Category: Research Source Type: clinical trials
Investigation of Drug-drug Interaction of Nintedanib and Ketoconazole in Healthy Male Volunteers
Condition: HealthyInterventions: Drug: Nintedanib; Drug: Nintedanib; Drug: Ketoconazole; Drug: Nintedanib; Drug: Nintedanib; Drug: KetoconazoleSponsor: Boehringer IngelheimCompleted - verified November 2014 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 3, 2012 Category: Research Source Type: clinical trials