P11 Real-World Evidence of Total Colonoscopy for Colorectal Cancer Screening Based on Test Performance RCTs
Total colonoscopy (TCS) has been anticipated as a new method for colorectal cancer screening. Although randomized control studies (RCTs) are ongoing, there has yet to be a conclusive result. We evaluated the effectiveness of TCS screening following the stepwise approach developed by the World Endoscopic Evaluation (WEO). (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: C. Hamashima, T. Terasaw, S. Hosono, T. Katayama, S. Sasaki, K. Abe, K. Hoshi, T. Tadano Source Type: research
P12 Screen-Detected Breast Cancers Have Improved 5-Year Disease Free Interval Compared to Interval and Non-Screen-Related Breast Cancer, Taking Lead Time into Account
We investigated the association between method of breast cancer detection and disease free interval (DFI), corrected for lead-time. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: A. Eijkelboom, L. de Munck, J.D.M. Otten, M.J.M. Broeders, S. Siesling Source Type: research
P5 An Update on Calcitonin Gene-Related Peptide Monoclonal Antibodies Reimbursed Under a Managed Access Protocol in Ireland
This study provides a summary of the number of applications for CGRP MABs submitted and an overview of the utilisation of CGRP MABs on the High Tech Arrangement. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: K. Finnigan, A. Smith, S. Clarke, M. Barry, C. Gorry Tags: The Impact of Cost-Containment Initiatives from across the Globe Source Type: research
P7 International Reference Pricing and Joint Clinical Assessments —How Will European-Level HTA Evaluations Impact International Reference Pricing and Launch Sequencing?
While international reference pricing (IRP) has traditionally been used to inform launch sequencing, European efforts to standardize the determination of clinical value for new products through joint clinical assessments (JCAs) are expected to impact launch preparedness. This research aims to analyze launch sequences of drugs to evaluate if launch preparedness is still heavily driven by IRP policies or is incorporating components to account for the future effects of JCAs. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: A. Saei, E. Tutulea, L. Perez-Kempner Source Type: research
P8 The Dutch Lock Procedure for Reimbursement Works as Intended
The Dutch government introduced a lock procedure in 2015 to regulate access of expensive hospital drugs to the market. The lock intents to prevent uptake of ineffective drugs and to negotiate the price of effective drugs to regulate the impact on the health care budget. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: J. Boer, W. van Straaten, Gin L. Tjon Joe, L. Boonen Source Type: research
P13 Carer Preferences and Willingness-to-Pay for Home Care Services for Older People With Dementia: A Discrete Choice Experiment in the Milan Metropolitan Area
This study aimed to elicit carer preferences and willingness-to-pay for alternative bundles of home care services in the Milan metropolitan area. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: M. Meregaglia, S. Manfredi, E. Perobelli, A. Rotolo, E. Donati, E. Notarnicola Tags: Using Discrete Choice Experiments to Elicit Carers' and Patients' Preferences Source Type: research
P14 Understanding Patients' Preferences for Remote Monitoring in Parkinson's Disease: Insights from a Mixed-Methods Study
This study aimed to bridge this gap by eliciting and examining PD patients' preferences for RPM through interviews and a discrete choice experiment (DCE). (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: C. Godoy, F. Miele, L. M äkitie, E. Fiorenzato, L.J. Bakker, Groot C Uyl-De, K. Redekop, W. van Deen Source Type: research
P15 Unraveling Acceptance of Healthcare Innovations in Neurorehabilitation: A Systematic Approach Through Health Preference Research
Strokes present a challenge to the healthcare system, as the absolute number of strokes has increased despite a decline in stroke-related mortality. The demand for neurorehabilitation is growing, necessitating innovative solutions due to a shortage of professionals. The utilization of digital technologies offers the potential for increased efficiency and effectiveness. However, patient acceptance plays a crucial role in the successful adoption. Therefore, this study aimed to systematically analyze patients acceptance for digital technologies in neurorehabilitation. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: A.K. Fischer, A.C. M ühlbacher Source Type: research
P16 What Trade-Offs Are Women Willing to Make When Choosing Between Potential Treatments for Moderate-to-Severe Vasomotor Symptoms Due to Menopause?
To elicit women ’s preferences for treatments of vasomotor symptoms (VMS) due to menopause. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: S. Heidenreich, K. Cutts, A. Doldos, L. Todorova, J. Kim, T. Hillard, T. Simoncini, T. Mikkola Source Type: research
P17 A Retrospective Analysis of Medicare Current Beneficiary Survey Data to Evaluate the Alzheimer's Disease and Related Dementia Risk-Reducing Benefits Offered By HMGCR Inhibitors or Statins
The objective of this analysis was to assess whether statins significantly reduce ADRD risk among older adults and, if so, which statin drugs offer the greatest ri sk reduction. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: M. Chanpura, A. Akincigil, Z. Khan Tags: Expanding Data Sources: Creative Use of Data in Health Economics Analyses Source Type: research
P18 Adjusted Comparison of Teclistamab Versus Real-World Physician ’s Choice (RWPC) of Therapy in Patients with Triple-Class Exposed (TCE) Relapsed/Refractory Multiple Myeloma (RRMM)
Patients with RRMM who receive ≥3 prior lines of therapy (LOT) have limited treatment options. Teclistamab is the only approved BCMA×CD3 bispecific antibody with a personalized, weight-based dosing schedule for the treatment of TCE RRMM. We assessed the comparative effectiveness of teclistamab vs RWPC of therapy. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: M.V. Mateos, A. Chari, S.Z. Usmani, H. Goldschmidt, K. Weisel, K. Qi, A. Londhe, S. Nair, X. Lin, L. Pei, E. Ammann, K. Chastain, T. Parekh, A. Marshall, M. Slavcev, P. Moreau Source Type: research
P19 Demographics of Patients and Societal Burden of Obstructive Hypertrophic Cardiomyopathy: Results From a Real-World Survey in Italy and Spain
To describe the clinical characteristics, burden of illness, productivity, and support needs of patients with obstructive hypertrophic cardiomyopathy (HCM) in Italy (IT) and Spain (ES). (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: M. Lowe, J. Jackson, K. Tebbs, Y. Zhong, M. Contente, S. Barlow, T. Krause Source Type: research
P20 Matching-Adjusted Indirect Treatment Comparison (MAIC) of Teclistamab Vs Belantamab Mafodotin for the Treatment of Patients with Triple-Class Exposed (TCE) Relapsed/Refractory Multiple Myeloma (RRMM)
Teclistamab is the only approved BCMA ×CD3 BsAb with a personalized, weight-based dosing schedule for the treatment of TCE RRMM. We assessed the comparative efficacy of teclistamab vs belantamab mafodotin for patients with TCE RRMM. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: P. Moreau, S.Z. Usmani, N.W.C.J. van de Donk, A.L. Garfall, M. Delforge, A. Oriol, A. Nooka, L. Rosi ñol, N. Bahlis, P. Rodriguez Otero, T.G. Martin, J. Diels, S. Van Sanden, L. Pei, E. Ammann, K. Chastain, A. Marshall, M. Slavcev, A. Londhe, A. Krishnan Source Type: research
P21 A Comparative Analysis of Large Language Models (LLM) Utilised in Systematic Literature Review
The objective of this study was to conduct a comparison of three Large Language Models (LLMs) — AI21 Ultra, OpenAI GPT-4, and Google Vertex Artificial Intelligence (AI) Model Bison in their application to primary screening during a systematic literature review (SLR). (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: H. Rathi, A. Malik, D.C. Behera, G. Kamboj Tags: Using Artificial Intelligence to Enhance Efficiency in Systematic Reviews and Meta-Analyses Source Type: research
P22 Disrupting Health Economics: Automating Network Meta-Analyses With AI and Large Language Models
The advancement of Large Language Models (LLMs), such as GPT-4, provides opportunities for automating data extraction and analysis in systematic reviews and meta-analyses. However, their practical application in Health Economics and Outcomes Research (HEOR) remains unverified. Our study aimed to evaluate GPT-4's accuracy in replicating a Network Meta-Analysis (NMA) result on overall survival of adult patients with advanced non-small cell lung cancer (NSCLC) post platinum-based treatment and pre-immunotherapy. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: T. Reason, B. Malcolm, S. Klijn, J. Langham, A. Gimblett, E. Benbow Source Type: research
