CROI 2023: Tuberculosis and Infectious Complications in Persons With HIV
Top Antivir Med. 2023 Jun 30;31(4):529-537.ABSTRACTNovel implementation strategies to increase uptake and adherence to tuberculosis (TB) preventive therapy hold promise for reducing TB incidence in persons with HIV in high-burden settings. In persons who develop drug-susceptible TB, progress to shorten TB treatment continues to be made with the introduction of new drugs and novel treatment strategies that could allow for treatment shortening to 2 months for most people. A global case series provided powerful evidence that mpox should be considered an HIV-related opportunistic infection given its severe manifestations and p...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Andrew D Kerkhoff Diane V Havlir Source Type: research
CROI 2023: Neuropsychiatric Complications in People With HIV
Top Antivir Med. 2023 Jun 30;31(4):543-555.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured new and impactful findings about neuropsychiatric complications in people with HIV and other infections. Reports included new evidence of (a) the importance of myeloid cells in the pathogenesis of HIV disease in the central nervous system, including as an HIV reservoir; (b) eukaryotic and prokaryotic viruses in cerebrospinal fluid during suppressive antiretroviral therapy; (c) the influence of sex on pathogenesis, including in novel neuropsychiatric biotypes identified by machine learning and ...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Albert M Anderson Beau M Ances Scott L Letendre Source Type: research
CROI 2023: Summary of Basic Science Research in HIV
Top Antivir Med. 2023 Jun 30;31(4):523-528.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) represented the first fully in-person conference since the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic began. CROI continues as the premier conference in which delegates can appraise themselves of almost every facet of HIV/AIDS research as well as emerging and re-emerging pathogens such as SARS-CoV-2 and mpox. The return to an in-person format is particularly important for early-stage investigators, who were faced with challenges of advancing their independent research careers...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Mario Stevenson Source Type: research
CROI 2023: Metabolic and Other Complications of HIV Infection
Top Antivir Med. 2023 Jun 30;31(4):538-542.ABSTRACTComorbid conditions have major impacts on the health, quality of life, and survival of people with HIV, particularly as they age. The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured excellent science related to specific comorbidities, such as cardiovascular disease (CVD), cancer, and obesity. Studies investigating factors that may contribute to CVD, such as mental health disorders, antiretroviral therapies, and activation of hormonal pathways, were featured prominently. Other studies sought to understand the epidemiology of non-AIDS-defining ca...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Sudipa Sarkar Todd T Brown Source Type: research
CROI 2023: Tuberculosis and Infectious Complications in Persons With HIV
Top Antivir Med. 2023 Jun 30;31(4):529-537.ABSTRACTNovel implementation strategies to increase uptake and adherence to tuberculosis (TB) preventive therapy hold promise for reducing TB incidence in persons with HIV in high-burden settings. In persons who develop drug-susceptible TB, progress to shorten TB treatment continues to be made with the introduction of new drugs and novel treatment strategies that could allow for treatment shortening to 2 months for most people. A global case series provided powerful evidence that mpox should be considered an HIV-related opportunistic infection given its severe manifestations and p...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Andrew D Kerkhoff Diane V Havlir Source Type: research
CROI 2023: Neuropsychiatric Complications in People With HIV
Top Antivir Med. 2023 Jun 30;31(4):543-555.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured new and impactful findings about neuropsychiatric complications in people with HIV and other infections. Reports included new evidence of (a) the importance of myeloid cells in the pathogenesis of HIV disease in the central nervous system, including as an HIV reservoir; (b) eukaryotic and prokaryotic viruses in cerebrospinal fluid during suppressive antiretroviral therapy; (c) the influence of sex on pathogenesis, including in novel neuropsychiatric biotypes identified by machine learning and ...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Albert M Anderson Beau M Ances Scott L Letendre Source Type: research
CROI 2023: Summary of Basic Science Research in HIV
Top Antivir Med. 2023 Jun 30;31(4):523-528.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) represented the first fully in-person conference since the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic began. CROI continues as the premier conference in which delegates can appraise themselves of almost every facet of HIV/AIDS research as well as emerging and re-emerging pathogens such as SARS-CoV-2 and mpox. The return to an in-person format is particularly important for early-stage investigators, who were faced with challenges of advancing their independent research careers...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Mario Stevenson Source Type: research
CROI 2023: Metabolic and Other Complications of HIV Infection
Top Antivir Med. 2023 Jun 30;31(4):538-542.ABSTRACTComorbid conditions have major impacts on the health, quality of life, and survival of people with HIV, particularly as they age. The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured excellent science related to specific comorbidities, such as cardiovascular disease (CVD), cancer, and obesity. Studies investigating factors that may contribute to CVD, such as mental health disorders, antiretroviral therapies, and activation of hormonal pathways, were featured prominently. Other studies sought to understand the epidemiology of non-AIDS-defining ca...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Sudipa Sarkar Todd T Brown Source Type: research
CROI 2023: Tuberculosis and Infectious Complications in Persons With HIV
Top Antivir Med. 2023 Jun 30;31(4):529-537.ABSTRACTNovel implementation strategies to increase uptake and adherence to tuberculosis (TB) preventive therapy hold promise for reducing TB incidence in persons with HIV in high-burden settings. In persons who develop drug-susceptible TB, progress to shorten TB treatment continues to be made with the introduction of new drugs and novel treatment strategies that could allow for treatment shortening to 2 months for most people. A global case series provided powerful evidence that mpox should be considered an HIV-related opportunistic infection given its severe manifestations and p...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Andrew D Kerkhoff Diane V Havlir Source Type: research
CROI 2023: Neuropsychiatric Complications in People With HIV
Top Antivir Med. 2023 Jun 30;31(4):543-555.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured new and impactful findings about neuropsychiatric complications in people with HIV and other infections. Reports included new evidence of (a) the importance of myeloid cells in the pathogenesis of HIV disease in the central nervous system, including as an HIV reservoir; (b) eukaryotic and prokaryotic viruses in cerebrospinal fluid during suppressive antiretroviral therapy; (c) the influence of sex on pathogenesis, including in novel neuropsychiatric biotypes identified by machine learning and ...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Albert M Anderson Beau M Ances Scott L Letendre Source Type: research
CROI 2023: Summary of Basic Science Research in HIV
Top Antivir Med. 2023 Jun 30;31(4):523-528.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) represented the first fully in-person conference since the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic began. CROI continues as the premier conference in which delegates can appraise themselves of almost every facet of HIV/AIDS research as well as emerging and re-emerging pathogens such as SARS-CoV-2 and mpox. The return to an in-person format is particularly important for early-stage investigators, who were faced with challenges of advancing their independent research careers...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Mario Stevenson Source Type: research
CROI 2023: Metabolic and Other Complications of HIV Infection
Top Antivir Med. 2023 Jun 30;31(4):538-542.ABSTRACTComorbid conditions have major impacts on the health, quality of life, and survival of people with HIV, particularly as they age. The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured excellent science related to specific comorbidities, such as cardiovascular disease (CVD), cancer, and obesity. Studies investigating factors that may contribute to CVD, such as mental health disorders, antiretroviral therapies, and activation of hormonal pathways, were featured prominently. Other studies sought to understand the epidemiology of non-AIDS-defining ca...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Sudipa Sarkar Todd T Brown Source Type: research
CROI 2023: Tuberculosis and Infectious Complications in Persons With HIV
Top Antivir Med. 2023 Jun 30;31(4):529-537.ABSTRACTNovel implementation strategies to increase uptake and adherence to tuberculosis (TB) preventive therapy hold promise for reducing TB incidence in persons with HIV in high-burden settings. In persons who develop drug-susceptible TB, progress to shorten TB treatment continues to be made with the introduction of new drugs and novel treatment strategies that could allow for treatment shortening to 2 months for most people. A global case series provided powerful evidence that mpox should be considered an HIV-related opportunistic infection given its severe manifestations and p...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Andrew D Kerkhoff Diane V Havlir Source Type: research
CROI 2023: Neuropsychiatric Complications in People With HIV
Top Antivir Med. 2023 Jun 30;31(4):543-555.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) featured new and impactful findings about neuropsychiatric complications in people with HIV and other infections. Reports included new evidence of (a) the importance of myeloid cells in the pathogenesis of HIV disease in the central nervous system, including as an HIV reservoir; (b) eukaryotic and prokaryotic viruses in cerebrospinal fluid during suppressive antiretroviral therapy; (c) the influence of sex on pathogenesis, including in novel neuropsychiatric biotypes identified by machine learning and ...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Albert M Anderson Beau M Ances Scott L Letendre Source Type: research
CROI 2023: Summary of Basic Science Research in HIV
Top Antivir Med. 2023 Jun 30;31(4):523-528.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) represented the first fully in-person conference since the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic began. CROI continues as the premier conference in which delegates can appraise themselves of almost every facet of HIV/AIDS research as well as emerging and re-emerging pathogens such as SARS-CoV-2 and mpox. The return to an in-person format is particularly important for early-stage investigators, who were faced with challenges of advancing their independent research careers...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Mario Stevenson Source Type: research
