Integrated molecular, phenotypic and epidemiological surveillance of antimicrobial resistance in Neisseria gonorrhoeae in Germany
Int J Med Microbiol. 2024 Jan 29;314:151611. doi: 10.1016/j.ijmm.2024.151611. Online ahead of print.ABSTRACTNumbers of infections with Neisseria gonorrhoeae are among the top three sexually transmitted infections (STI) worldwide. In addition, the emergence and spread of antimicrobial resistance (AMR) in Neisseria gonorrhoeae pose an important public-health issue. The integration of genomic, phenotypic and epidemiological data to monitor Neisseria gonorrhoeae fosters our understanding of the emergence and spread of AMR in Neisseria gonorrhoeae and helps to inform therapy guidelines and intervention strategies. Thus, the Gon...
Source: Topics in HIV Medicine - February 3, 2024 Category: Infectious Diseases Authors: Kathleen Klaper Hana Tlap ák Regina Selb Klaus Jansen Dagmar Heuer Source Type: research

Recent Developments and Future Perspectives of Purine Derivatives as a Promising Scaffold in Drug Discovery
Curr Top Med Chem. 2024 Jan 26. doi: 10.2174/0115680266290152240110074034. Online ahead of print.ABSTRACTNumerous purine-containing compounds have undergone extensive investigation for their medical efficacy across various diseases. The swift progress in purine-based medicinal chemistry has brought to light the therapeutic capabilities of purine-derived compounds in addressing challenging medical conditions. Defined by a heterocyclic ring comprising a pyrimidine ring linked with an imidazole ring, purine exhibits a diverse array of therapeutic attributes. This review systematically addresses the multifaceted potential of p...
Source: Topics in HIV Medicine - January 30, 2024 Category: Infectious Diseases Authors: Neha Rana Parul Grover Hridayanand Singh Source Type: research

Tuberculosis in Sudan: systematic review and meta analysis
BMC Pulm Med. 2024 Jan 23;24(1):51. doi: 10.1186/s12890-024-02865-6.ABSTRACTEvery year, 10 million people fall ill with tuberculosis (TB). Despite being a preventable and curable disease, 1.5 million people die from TB each year -making it the world's top infectious disease. TB is the leading cause of death of people with HIV and also a major contributor to antimicrobial resistance. Its presumed that TB was the cause of 1% of the total deaths among inpatients in Sudan in 2017. The current study is aimed to provide pooled prevalence of Mycobacterium tuberculosis among Sudanese as well as to determine any socio-cultural risk...
Source: Topics in HIV Medicine - January 23, 2024 Category: Infectious Diseases Authors: M M Badawi M A SalahEldin A B Idris E B Idris S G Mohamed Source Type: research

Prevention and treatment of cardiovascular disease in HIV: practical insights in an evolving field
Top Antivir Med. 2023 Dec 5;31(5):559-565.ABSTRACTPeople with HIV (PWH) are at higher risk for cardiovascular disease (CVD) than people without HIV. As antiretroviral therapy (ART) and the natural history of HIV have evolved, so have the pathogenesis and manifestations of HIV-associated CVD. Epidemiologic data from several cohorts demonstrate that PWH have an approximately 50% higher risk than people without HIV for CVD, including, but not limited to, myocardial infarction and heart failure. This elevated CVD risk is not universal among PWH; for instance, the risk is higher among individuals with a history of sustained uns...
Source: Topics in HIV Medicine - January 10, 2024 Category: Infectious Diseases Authors: Harris Avgousti Matthew J Feinstein Source Type: research

2023 updated guidelines on infant feeding and HIV in the United States: what are they and why have recommendations changed
Top Antivir Med. 2023 Dec 5;31(5):576-586.ABSTRACTThe US Department of Health and Human Services guidelines on infant feeding among people with HIV have changed in response to (1) evidence of low risk of transmission via breast milk among individuals with consistent viral suppression, (2) considerations of equity and cultural norms, and (3) community desires. The 2023 guidelines recommend patient-centered shared decision-making. Individuals with HIV who are receiving antiretroviral therapy (ART) and have consistent viral suppression should be counseled on the options of for-mula feeding, feeding with banked donor milk, or ...
Source: Topics in HIV Medicine - January 10, 2024 Category: Infectious Diseases Authors: Lealah Pollock July Levison Source Type: research

Advances in HIV self-testing: Systematic review of current developments and the road ahead in high-burden countries of Africa
CONCLUSION: Adopting HIV self-testing by overcoming the challenging potential barriers could enable early detection, care, treatment, and prevention of the disease to achieve the 95-95-95 goal by 2030. Further study is necessary to explore the actual practices related to HIV self-testing among different populations in Africa.PMID:38162911 | PMC:PMC10757441 | DOI:10.1177/20503121231220788 (Source: Topics in HIV Medicine)
Source: Topics in HIV Medicine - January 1, 2024 Category: Infectious Diseases Authors: Habtamu Mekonnen Tsegahun Manyazewal Violet Dismas Kajogoo Dawit Getachew Assefa Jilcha Gugsa Bekele Dejene Tolossa Debela Source Type: research

Advances in HIV self-testing: Systematic review of current developments and the road ahead in high-burden countries of Africa
CONCLUSION: Adopting HIV self-testing by overcoming the challenging potential barriers could enable early detection, care, treatment, and prevention of the disease to achieve the 95-95-95 goal by 2030. Further study is necessary to explore the actual practices related to HIV self-testing among different populations in Africa.PMID:38162911 | PMC:PMC10757441 | DOI:10.1177/20503121231220788 (Source: Topics in HIV Medicine)
Source: Topics in HIV Medicine - January 1, 2024 Category: Infectious Diseases Authors: Habtamu Mekonnen Tsegahun Manyazewal Violet Dismas Kajogoo Dawit Getachew Assefa Jilcha Gugsa Bekele Dejene Tolossa Debela Source Type: research

Advances in HIV self-testing: Systematic review of current developments and the road ahead in high-burden countries of Africa
CONCLUSION: Adopting HIV self-testing by overcoming the challenging potential barriers could enable early detection, care, treatment, and prevention of the disease to achieve the 95-95-95 goal by 2030. Further study is necessary to explore the actual practices related to HIV self-testing among different populations in Africa.PMID:38162911 | PMC:PMC10757441 | DOI:10.1177/20503121231220788 (Source: Topics in HIV Medicine)
Source: Topics in HIV Medicine - January 1, 2024 Category: Infectious Diseases Authors: Habtamu Mekonnen Tsegahun Manyazewal Violet Dismas Kajogoo Dawit Getachew Assefa Jilcha Gugsa Bekele Dejene Tolossa Debela Source Type: research

Advances in HIV self-testing: Systematic review of current developments and the road ahead in high-burden countries of Africa
CONCLUSION: Adopting HIV self-testing by overcoming the challenging potential barriers could enable early detection, care, treatment, and prevention of the disease to achieve the 95-95-95 goal by 2030. Further study is necessary to explore the actual practices related to HIV self-testing among different populations in Africa.PMID:38162911 | PMC:PMC10757441 | DOI:10.1177/20503121231220788 (Source: Topics in HIV Medicine)
Source: Topics in HIV Medicine - January 1, 2024 Category: Infectious Diseases Authors: Habtamu Mekonnen Tsegahun Manyazewal Violet Dismas Kajogoo Dawit Getachew Assefa Jilcha Gugsa Bekele Dejene Tolossa Debela Source Type: research

Advances in HIV self-testing: Systematic review of current developments and the road ahead in high-burden countries of Africa
CONCLUSION: Adopting HIV self-testing by overcoming the challenging potential barriers could enable early detection, care, treatment, and prevention of the disease to achieve the 95-95-95 goal by 2030. Further study is necessary to explore the actual practices related to HIV self-testing among different populations in Africa.PMID:38162911 | PMC:PMC10757441 | DOI:10.1177/20503121231220788 (Source: Topics in HIV Medicine)
Source: Topics in HIV Medicine - January 1, 2024 Category: Infectious Diseases Authors: Habtamu Mekonnen Tsegahun Manyazewal Violet Dismas Kajogoo Dawit Getachew Assefa Jilcha Gugsa Bekele Dejene Tolossa Debela Source Type: research

Advances in HIV self-testing: Systematic review of current developments and the road ahead in high-burden countries of Africa
CONCLUSION: Adopting HIV self-testing by overcoming the challenging potential barriers could enable early detection, care, treatment, and prevention of the disease to achieve the 95-95-95 goal by 2030. Further study is necessary to explore the actual practices related to HIV self-testing among different populations in Africa.PMID:38162911 | PMC:PMC10757441 | DOI:10.1177/20503121231220788 (Source: Topics in HIV Medicine)
Source: Topics in HIV Medicine - January 1, 2024 Category: Infectious Diseases Authors: Habtamu Mekonnen Tsegahun Manyazewal Violet Dismas Kajogoo Dawit Getachew Assefa Jilcha Gugsa Bekele Dejene Tolossa Debela Source Type: research

Migration in French Guiana: Implications in health and infectious diseases
Travel Med Infect Dis. 2023 Dec 3;57:102677. doi: 10.1016/j.tmaid.2023.102677. Online ahead of print.ABSTRACTIn French Guiana, more than a third of the population, and nearly half of the adults, are of foreign origin. This immigration is explained by the French standard of living, which is attractive to nationals of surrounding countries. Infectious diseases remain in the top 10 causes of premature death, often in the most precarious populations. In this context we aimed to synthesize the state of the knowledge regarding immigration and infectious diseases in French Guiana and the general implications that follow this diag...
Source: Topics in HIV Medicine - December 4, 2023 Category: Infectious Diseases Authors: Mathieu Nacher Lo ïc Epelboin Timoth ée Bonifay F élix Djossou Romain Blaizot Pierre Couppi é Antoine Adenis Aude Lucarelli Yann Lambert Roxane Schaub Maylis Douine Source Type: research

Migration in French Guiana: Implications in health and infectious diseases
Travel Med Infect Dis. 2023 Dec 3;57:102677. doi: 10.1016/j.tmaid.2023.102677. Online ahead of print.ABSTRACTIn French Guiana, more than a third of the population, and nearly half of the adults, are of foreign origin. This immigration is explained by the French standard of living, which is attractive to nationals of surrounding countries. Infectious diseases remain in the top 10 causes of premature death, often in the most precarious populations. In this context we aimed to synthesize the state of the knowledge regarding immigration and infectious diseases in French Guiana and the general implications that follow this diag...
Source: Topics in HIV Medicine - December 4, 2023 Category: Infectious Diseases Authors: Mathieu Nacher Lo ïc Epelboin Timoth ée Bonifay F élix Djossou Romain Blaizot Pierre Couppi é Antoine Adenis Aude Lucarelli Yann Lambert Roxane Schaub Maylis Douine Source Type: research

Migration in French Guiana: Implications in health and infectious diseases
Travel Med Infect Dis. 2023 Dec 3;57:102677. doi: 10.1016/j.tmaid.2023.102677. Online ahead of print.ABSTRACTIn French Guiana, more than a third of the population, and nearly half of the adults, are of foreign origin. This immigration is explained by the French standard of living, which is attractive to nationals of surrounding countries. Infectious diseases remain in the top 10 causes of premature death, often in the most precarious populations. In this context we aimed to synthesize the state of the knowledge regarding immigration and infectious diseases in French Guiana and the general implications that follow this diag...
Source: Topics in HIV Medicine - December 4, 2023 Category: Infectious Diseases Authors: Mathieu Nacher Lo ïc Epelboin Timoth ée Bonifay F élix Djossou Romain Blaizot Pierre Couppi é Antoine Adenis Aude Lucarelli Yann Lambert Roxane Schaub Maylis Douine Source Type: research

Migration in French Guiana: Implications in health and infectious diseases
Travel Med Infect Dis. 2023 Dec 3;57:102677. doi: 10.1016/j.tmaid.2023.102677. Online ahead of print.ABSTRACTIn French Guiana, more than a third of the population, and nearly half of the adults, are of foreign origin. This immigration is explained by the French standard of living, which is attractive to nationals of surrounding countries. Infectious diseases remain in the top 10 causes of premature death, often in the most precarious populations. In this context we aimed to synthesize the state of the knowledge regarding immigration and infectious diseases in French Guiana and the general implications that follow this diag...
Source: Topics in HIV Medicine - December 4, 2023 Category: Infectious Diseases Authors: Mathieu Nacher Lo ïc Epelboin Timoth ée Bonifay F élix Djossou Romain Blaizot Pierre Couppi é Antoine Adenis Aude Lucarelli Yann Lambert Roxane Schaub Maylis Douine Source Type: research