Synthetic nicotine has arrived
The introduction of a new product line of the popular disposable electronic cigarette brand Puffbar, advertised as containing synthetic nicotine, has drawn attention to the increasing use of synthetic nicotine in marketed products and its uncertain regulatory status. A search of the Truth Tobacco Industry Documents revealed that the industry considered using synthetic nicotine already in the 1960s, efforts that were abandoned due to high costs and insufficient purity. Recent patents revealed renewed efforts to develop more efficient strategies for the synthesis of nicotine. Nicotine exists as two stereoisomers, S-nicotine ...
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Jordt, S.-E. Tags: Open access Special communication Source Type: research

Marketing of flavour capsule cigarettes: a systematic review
Conclusion Findings illuminate the marketing strategies of FCVs that are likely driving their global growth, particularly among young people and in low and middle-income countries. Comprehensive tobacco control regulations are needed to close loopholes and curb industry efforts to circumvent existing policies in order to mitigate uptake of FCVs and other product innovations. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Kyriakos, C. N., Zatonski, M. Z., Filippidis, F. T. Tags: Review Source Type: research

Sensory methods to evaluate perception of flavours in tobacco and other nicotine-containing products: a review
Conclusions The identified studies highlight that sensory data can inform ToNic product policy. Analytic and sensory hedonic ratings can be used to assess a ToNic product’s ability to promote addiction in the user (ie, abuse liability). Lastly, hedonic ratings can provide information to assess potential use behaviours. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Bernat, J. K., Jackson, K. J., Krüsemann, E. J. Z., Boesveldt, S., Rudy, S. F., Talhout, R. Tags: Review Source Type: research

Flavour capsule cigarette use and perceptions: a systematic review
Conclusion Findings call for the adoption of comprehensive tobacco control policies that account for flavour capsules and similar iterations, which can increase appeal through flavours and innovative features. Continued monitoring and research of these products is critical, with particular attention to low-income and middle-income countries, which make up a disproportionately larger share of the capsule market. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Kyriakos, C. N., Zatonski, M. Z., Filippidis, F. T. Tags: Open access Review Source Type: research

Comprehensive Dutch market data analysis shows that e-liquids with nicotine salts have both higher nicotine and flavour concentrations than those with free-base nicotine
Conclusions A substantial and increasing share of e-liquids in the Netherlands contains nicotine salts. Their characteristics can make such e-liquids more addictive and more attractive, especially to young and beginning users. Policymakers are advised to consider regulating products containing nicotine salts. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Pennings, J. L. A., Havermans, A., Pauwels, C. G. G. M., Krüsemann, E. J. Z., Visser, W. F., Talhout, R. Tags: Open access Original research Source Type: research

Flavour spectrum of the Puff family of disposable e-cigarettes
Conclusions The proliferation of flavoured disposable e-cigarette products, many of which are designed to emulate popular pod devices, illustrates that narrowly limited flavour regulations covering only a single category are destined to fail. To be effective in youth protection, flavour regulations need to apply to all recreational nicotine-containing products and need to include measures to counter post-market flavour addition. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Ramamurthi, D., Chau, C., Berke, H. Y., Tolba, A. M., Yuan, L., Kanchan, V., Santos, G., Jackler, R. K. Tags: Original research Source Type: research

Classifying the comprehensiveness of flavoured tobacco sales restrictions: development and application of a tool to examine US state and local tobacco policies
Conclusions Comprehensiveness of FTP sales restrictions in the USA varies widely. Current and future FTP policies would be strengthened by including all flavours and all tobacco products—particularly menthol cigarettes—and by avoiding exemptions for certain retailers, particularly adult-only retailers. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Donovan, E., Folger, S., Akbar, M., Schillo, B. Tags: Editor's choice Original research Source Type: research

Tobacco industry strategies for flavour capsule cigarettes: analysis of patents and internal industry documents
Conclusions To prevent tobacco companies from targeting young people and exploiting regulatory loopholes, regulations on tobacco products should ban flavours and consider the broad variety of FCV designs, additives and loose products designed to impart flavour into tobacco products. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: van der Eijk, Y., Teo, K. W., Tan, G. P. P., Chua, W. M. Tags: Original research Source Type: research

Addicted to green: priming effect of menthol cigarette packaging on brain response to smoking cues
Conclusions Our findings demonstrate heightened motivational and perceptual salience of the green-hued menthol cigarette packaging that may exacerbate menthol smokers’ susceptibility to smoking cues. These effects could contribute to the greater addiction severity among menthol smokers and could be considered in the development of science-based regulation and legal review of tobacco product marketing practices. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Shi, Z., Wang, A.-L., Fairchild, V. P., Aronowitz, C. A., Lynch, K. G., Loughead, J., Langleben, D. D. Tags: Original research Source Type: research

Public health impact of a US ban on menthol in cigarettes and cigars: a simulation study
Conclusions and relevance Our findings strongly support the implementation of a ban on menthol in cigarettes and cigars. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Levy, D. T., Meza, R., Yuan, Z., Li, Y., Cadham, C., Sanchez-Romero, L. M., Travis, N., Knoll, M., Liber, A. C., Mistry, R., Hirschtick, J. L., Fleischer, N. L., Skolnick, S., Brouwer, A. F., Douglas, C., Jeon, J., Cook, S., Warner, K. E. Tags: Open access Original research Source Type: research

Effects of menthol use and transitions in use on short-term and long-term cessation from cigarettes among US smokers
Conclusion These results demonstrate that menthol impaired menthol smokers’ attempts to quit smoking but switching from menthol improved success. This suggests that removing menthol may improve menthol smokers’ success during quit attempts. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Leas, E. C., Benmarhnia, T., Strong, D. R., Pierce, J. P. Tags: Original research Source Type: research

Impact of flavours, device, nicotine levels and price on adult e-cigarette users tobacco and nicotine product choices
Conclusions People are unlikely to switch to another product/device because of the restriction of flavour or nicotine level. If non-tobacco and non-menthol flavours were banned from open-system e-cigarettes, users may switch to menthol flavour e-cigarettes. Intervention strategies should be tailored to specific groups. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Yang, Y., Lindblom, E. N., Salloum, R. G., Ward, K. D. Tags: Original research Source Type: research

Colours, capsules and concept flavour names on cigarette packs appeal to youth in Mexico
Conclusions Colours and flavour capsule images appeal to adolescents and adults in Mexico. Mexico should consider adopting plain packaging to reduce appeal and interest. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Brown, J. L., Grilo, G., Cohen, J. E., Clegg Smith, K., Reynales-Shigematsu, L. M., Flores Escartin, M. G., Moran, M. B. Tags: Open access Original research Source Type: research

Recent, national trends in US adolescent use of menthol and non-menthol cigarettes
Conclusions Continuing declines in adolescent menthol prevalence indicate that both menthol prevalence and also black/non-black disparities in its use are steadily decreasing. However, these decreases in adolescence will take decades to reach later ages through generational replacement. Efforts to accelerate menthol decreases will require new initiatives to increase cessation among adult menthol users. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Miech, R. A., Leventhal, A. M., Johnson, L. D. Tags: Original research Source Type: research

Effects of electronic cigarette e-liquid flavouring on cigarette craving
Conclusions We did not find evidence to suggest that nicotine-containing fruit/sweet-flavoured and unflavoured e-liquids have different effects on cigarette cravings after 1 week of use. Further research is needed to establish if differences emerge over longer periods of exposure and extend to smoking cessation outcomes. (Source: Tobacco Control)
Source: Tobacco Control - March 17, 2023 Category: Respiratory Medicine Authors: Dyer, M. L., Khouja, J. N., Jackson, A. R., Havill, M. A., Dockrell, M. J., Munafo, M. R., Attwood, A. S. Tags: Open access Original research Source Type: research