Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Predictive factors for acceptance of a long-acting opiate substitution treatment studied through social representations and internalized stigma
CONCLUSIONS: We observed significant differences in social representations but not in internalized stigma between the two groups. Moreover, the predictive factors linked to the acceptance of a new SC form of OST suggest a multifactorial combination of elements that will have to be tested in a larger and prospective study delivering long-acting high-dose buprenorphine.PMID:37625937 | DOI:10.1016/j.therap.2023.07.006 (Source: Therapie)
Source: Therapie - August 25, 2023 Category: Psychiatry & Psychology Authors: Aur élie Lacroix Victor Puybaret Pierre Vill éger Juliette Zattoni-Leroy Sylvain Cantaloube Catherine Chevalier Philippe Nubukpo Source Type: research
Prescription-free consultation: A cross-sectional study in general practice
CONCLUSION: Acute consultations limit prescription-free consultations. General practitioners (GPs) probably overestimate patients' expectation of drug prescription. The French GP must be supported in their decision to not prescribe drugs. This is a long-term investment of time, to educate patients and avoid new consultations for acute reasons. A tool to help doctors manage non-prescription during acute consultations will be created in a future study in France.PMID:37625938 | DOI:10.1016/j.therap.2023.07.003 (Source: Therapie)
Source: Therapie - August 25, 2023 Category: Psychiatry & Psychology Authors: Am élie Richard Élodie Charuel S ébastien Cambier Manon Turpin Bruno Baudin Jos é-Philippe Moreno H élène Vaillant-Roussel Source Type: research
Statins and immune-mediated necrotizing myopathy: Variability in the risk
CONCLUSION: Atorvastatin presents the highest risk of IMNM. Our data suggest that the occurrence of IMNM is a class effect.PMID:37625939 | DOI:10.1016/j.therap.2023.07.005 (Source: Therapie)
Source: Therapie - August 25, 2023 Category: Psychiatry & Psychology Authors: Thierry Trenque Jed Hadjoudj Agathe Trenque Federica Tralongo Salom é Martin Brahim Azzouz Source Type: research
