Drug-induced fetal and offspring disorders, beyond birth defects
Therapie. 2023 Nov 14:S0040-5957(23)00182-8. doi: 10.1016/j.therap.2023.11.002. Online ahead of print.ABSTRACTStudies on drug utilization in western countries disclosed that about nine over ten women use at least one or more drugs during pregnancy. Determining whether a drug is safe or not in pregnant women is a challenge of all times. As a developing organism, the fetus is particularly vulnerable to effects of drugs used by the mother. Historically, research has predominantly focused on birth defects, which represent the most studied adverse pregnancy outcomes. However, drugs can also alter the ongoing process of pregnanc...
Source: Therapie - November 26, 2023 Category: Psychiatry & Psychology Authors: Margaux Louchet Myl ène Tisseyre Florentia Kaguelidou Jean-Marc Treluyer Laure-H élène Préta Laurent Chouchana Source Type: research

Validation of the French version of the Assessment Tool for Hospital Admissions Related to Medications (AT-HARM10) to detect drug-related hospitalizations
The objective of this work was to validate the French version of the AT-HARM10 tool in order to use it for patients admitted in our healthcare facilities. The tool has 10 questions. A positive response to any of the first 3 questions identify admissions that are unlikely to be drug-related. A positive response to one of the following 7 questions identify possible medication-related admissions. For semantic and linguistic validation, we performed cross-validation with forward-backward translation. To clinically validate the method, we conducted a retrospective study including patients over 65 admitted to short-stay units (U...
Source: Therapie - November 26, 2023 Category: Psychiatry & Psychology Authors: H éloïse Capelle Coralie Baldin Pierre Caunes Isabelle Pons C éline Meguerditchian Jean-No ël Argenson Aur élie Daumas Guillaume Hache Source Type: research

A revisited version of the disputatio for pharmacological training: An educational study
CONCLUSION: The disputatio is an innovative training program whose pedagogical and human values were underlined by most of the participants. Beyond pharmacology and therapeutics, the principle of disputatio could be extended to other disciplines, spanning the centuries.PMID:38008601 | DOI:10.1016/j.therap.2023.10.016 (Source: Therapie)
Source: Therapie - November 26, 2023 Category: Psychiatry & Psychology Authors: Louise Carton Romain Bordy Perle Totoson Edouard-Jules Laforgue Jean-Marc Pelerin Thomas Portier-Feunteun Sabine Mainbourg Dominique Deplanque Luc Zimmer Silvy Laporte R égis Bordet Guillaume Grenet Samuel Legeay Source Type: research

Drug-induced fetal and offspring disorders, beyond birth defects
Therapie. 2023 Nov 14:S0040-5957(23)00182-8. doi: 10.1016/j.therap.2023.11.002. Online ahead of print.ABSTRACTStudies on drug utilization in western countries disclosed that about nine over ten women use at least one or more drugs during pregnancy. Determining whether a drug is safe or not in pregnant women is a challenge of all times. As a developing organism, the fetus is particularly vulnerable to effects of drugs used by the mother. Historically, research has predominantly focused on birth defects, which represent the most studied adverse pregnancy outcomes. However, drugs can also alter the ongoing process of pregnanc...
Source: Therapie - November 26, 2023 Category: Psychiatry & Psychology Authors: Margaux Louchet Myl ène Tisseyre Florentia Kaguelidou Jean-Marc Treluyer Laure-H élène Préta Laurent Chouchana Source Type: research

Validation of the French version of the Assessment Tool for Hospital Admissions Related to Medications (AT-HARM10) to detect drug-related hospitalizations
The objective of this work was to validate the French version of the AT-HARM10 tool in order to use it for patients admitted in our healthcare facilities. The tool has 10 questions. A positive response to any of the first 3 questions identify admissions that are unlikely to be drug-related. A positive response to one of the following 7 questions identify possible medication-related admissions. For semantic and linguistic validation, we performed cross-validation with forward-backward translation. To clinically validate the method, we conducted a retrospective study including patients over 65 admitted to short-stay units (U...
Source: Therapie - November 26, 2023 Category: Psychiatry & Psychology Authors: H éloïse Capelle Coralie Baldin Pierre Caunes Isabelle Pons C éline Meguerditchian Jean-No ël Argenson Aur élie Daumas Guillaume Hache Source Type: research

A revisited version of the disputatio for pharmacological training: An educational study
CONCLUSION: The disputatio is an innovative training program whose pedagogical and human values were underlined by most of the participants. Beyond pharmacology and therapeutics, the principle of disputatio could be extended to other disciplines, spanning the centuries.PMID:38008601 | DOI:10.1016/j.therap.2023.10.016 (Source: Therapie)
Source: Therapie - November 26, 2023 Category: Psychiatry & Psychology Authors: Louise Carton Romain Bordy Perle Totoson Edouard-Jules Laforgue Jean-Marc Pelerin Thomas Portier-Feunteun Sabine Mainbourg Dominique Deplanque Luc Zimmer Silvy Laporte R égis Bordet Guillaume Grenet Samuel Legeay Source Type: research

Évaluation des dispositifs médicaux numériques : comment prendre en compte les spécificités de ces solutions ?
Therapie. 2023 Oct 29:S0040-5957(23)00155-5. doi: 10.1016/j.therap.2023.10.005. Online ahead of print.NO ABSTRACTPMID:37996273 | DOI:10.1016/j.therap.2023.10.005 (Source: Therapie)
Source: Therapie - November 23, 2023 Category: Psychiatry & Psychology Authors: Anouk Trancart Valery-Pierre Riche Antoine Disset Doroth ée Camus Anne Josseran Pascal B écache C écile Charle-Maachi Laure De Place Arthur Denninger J érôme Fabiano Charlotte Gourio Vincent Vercamer Source Type: research

Évaluation des dispositifs médicaux numériques : comment prendre en compte les spécificités de ces solutions ?
Therapie. 2023 Oct 29:S0040-5957(23)00155-5. doi: 10.1016/j.therap.2023.10.005. Online ahead of print.NO ABSTRACTPMID:37996273 | DOI:10.1016/j.therap.2023.10.005 (Source: Therapie)
Source: Therapie - November 23, 2023 Category: Psychiatry & Psychology Authors: Anouk Trancart Valery-Pierre Riche Antoine Disset Doroth ée Camus Anne Josseran Pascal B écache C écile Charle-Maachi Laure De Place Arthur Denninger J érôme Fabiano Charlotte Gourio Vincent Vercamer Source Type: research

Évaluation des dispositifs médicaux numériques : comment prendre en compte les spécificités de ces solutions ?
Therapie. 2023 Oct 29:S0040-5957(23)00155-5. doi: 10.1016/j.therap.2023.10.005. Online ahead of print.NO ABSTRACTPMID:37996273 | DOI:10.1016/j.therap.2023.10.005 (Source: Therapie)
Source: Therapie - November 23, 2023 Category: Psychiatry & Psychology Authors: Anouk Trancart Valery-Pierre Riche Antoine Disset Doroth ée Camus Anne Josseran Pascal B écache C écile Charle-Maachi Laure De Place Arthur Denninger J érôme Fabiano Charlotte Gourio Vincent Vercamer Source Type: research

Comment prendre en compte la dimension éco-responsable des produits de santé tout au long de leur cycle de vie?
Therapie. 2023 Nov 3:S0040-5957(23)00178-6. doi: 10.1016/j.therap.2023.10.012. Online ahead of print.NO ABSTRACTPMID:37993369 | DOI:10.1016/j.therap.2023.10.012 (Source: Therapie)
Source: Therapie - November 22, 2023 Category: Psychiatry & Psychology Authors: Bruno Laviolle Pierre-Fr édéric Degon C écile Gillet-Giraud Dominique Thiveaud Philippe Lechat Vera Bo ïko-Alaux Claire Fougerou Clara Jolly Abir Petit Isabelle R émy-Jouet Rapha ël Yven Laurence Bouret Laurie Marrauld Marie-Pierre Vaslet Virginie D Source Type: research

Comment prendre en compte la dimension éco-responsable des produits de santé tout au long de leur cycle de vie?
Therapie. 2023 Nov 3:S0040-5957(23)00178-6. doi: 10.1016/j.therap.2023.10.012. Online ahead of print.NO ABSTRACTPMID:37993369 | DOI:10.1016/j.therap.2023.10.012 (Source: Therapie)
Source: Therapie - November 22, 2023 Category: Psychiatry & Psychology Authors: Bruno Laviolle Pierre-Fr édéric Degon C écile Gillet-Giraud Dominique Thiveaud Philippe Lechat Vera Bo ïko-Alaux Claire Fougerou Clara Jolly Abir Petit Isabelle R émy-Jouet Rapha ël Yven Laurence Bouret Laurie Marrauld Marie-Pierre Vaslet Virginie D Source Type: research

Quelles actions pour lutter contre la d ésinformation sur les produits de santé ?
Therapie. 2023 Oct 29:S0040-5957(23)00154-3. doi: 10.1016/j.therap.2023.10.004. Online ahead of print.NO ABSTRACTPMID:37985308 | DOI:10.1016/j.therap.2023.10.004 (Source: Therapie)
Source: Therapie - November 20, 2023 Category: Psychiatry & Psychology Authors: Jo ëlle Micallef Herv é Maisonneuve Sophie Muller Mathieu Molimard Bernard B égaud Sandrine Cabut Mina Daban Milou-Daniel Drici Chantal Gatignol Anne Grumblat Catherine Guaspare-Cartron Bruno Lasserre Adel Mebarki Catherine Pons Fr édérique Prabonnau Source Type: research

Comit é de surveillance indépendant dans les essais cliniques : de la justification scientifique à l’organisation
Therapie. 2023 Nov 3:S0040-5957(23)00179-8. doi: 10.1016/j.therap.2023.10.013. Online ahead of print.NO ABSTRACTPMID:37985309 | DOI:10.1016/j.therap.2023.10.013 (Source: Therapie)
Source: Therapie - November 20, 2023 Category: Psychiatry & Psychology Authors: Clara Locher Silvy Laporte Peggy Derambure Olivier Chassany C écile Girault Alix Avakiantz Claire Bahans Dominique Deplanque Pierre Fustier Anne-Fran çoise Germe Behrouz Kassa ï Louis Lacoste Nadine Petitpain Matthieu Roustit Tabassome Simon C écile T Source Type: research

Drug-induced hyperglycemia and diabetes
CONCLUSIONS: The risks of induced hyperglycemia vary from one drug to another, and the underlying mechanisms are multiple and potentially complex. Clinicians need to be vigilant when using at-risk drugs in order to detect and manage these adverse drug reactions. However, it is to emphasize that the benefits of appropriately prescribed treatments most often outweigh their metabolic risks.PMID:37985310 | DOI:10.1016/j.therap.2023.09.010 (Source: Therapie)
Source: Therapie - November 20, 2023 Category: Psychiatry & Psychology Authors: Marie-Anne Heurtebize Jean-Luc Faillie Source Type: research

Quelles actions pour lutter contre la d ésinformation sur les produits de santé ?
Therapie. 2023 Oct 29:S0040-5957(23)00154-3. doi: 10.1016/j.therap.2023.10.004. Online ahead of print.NO ABSTRACTPMID:37985308 | DOI:10.1016/j.therap.2023.10.004 (Source: Therapie)
Source: Therapie - November 20, 2023 Category: Psychiatry & Psychology Authors: Jo ëlle Micallef Herv é Maisonneuve Sophie Muller Mathieu Molimard Bernard B égaud Sandrine Cabut Mina Daban Milou-Daniel Drici Chantal Gatignol Anne Grumblat Catherine Guaspare-Cartron Bruno Lasserre Adel Mebarki Catherine Pons Fr édérique Prabonnau Source Type: research