Human papillomavirus ‐independent cervical cancer and its precursor lesions
AbstractKey content
With the move towards ubiquitous human papillomavirus (HPV) primary screening and increasing coverage with HPV vaccination, the prevalence of HPV-associated cervical cancers is predicted to decrease.
Clinicians must be aware of HPV-independent adenocarcinomas, which are likely to increase as a proportion of the total diagnosed cervical adenocarcinomas.
Advances in histopathology, immunohistochemistry and molecular genetics have increased our understanding of the spectrum of gastric-type and other rare HPV-independent adenocarcinomas.
Clinical outcome and prognosis of HPV-independent adenocarcinoma is wo...
Source: The Obstetrician and Gynaecologist - December 14, 2022 Category: OBGYN Authors: Ieera Madan Aggarwal,
Yen Ching Yeo,
Zheng Yuan Ng Tags: Review Source Type: research
Facilitating HIV testing in colposcopy clinics to improve identification of HIV in a hidden population
(Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - December 10, 2022 Category: OBGYN Authors: Emily Keating,
Sophie Forsyth,
Jessica Daniel,
Emma Torbe Tags: Commentary Source Type: research
Spotlight on … … … maternal medicine
(Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - December 8, 2022 Category: OBGYN Authors: Kate Harding Tags: Short Communication Source Type: research
Facilitating HIV testing in colposcopy clinics to improve identification of HIV in a hidden population
(Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - December 3, 2022 Category: OBGYN Authors: Emily Keating,
Sophie Forsyth,
Jessica Daniel,
Emma Torbe Tags: Commentary Source Type: research
Postpartum perineal wound dehiscence
(Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - December 2, 2022 Category: OBGYN Authors: Tarek El Shamy,
Eleanor Sein,
Sunita Sharma,
Claudine Domoney Tags: Tips and Techniques Source Type: research
Manuscript title: Pitfalls of prenatal diagnosis associated with mosaicism
Discussion of the limitations and implications is essential and referral to clinical genetics may be warranted.Learning objectives• To understand the embryological causes for and types of fetal placental mosaicism.• To appreciate underlying principles in NIPT and genomic testing strategies in relation to mosaicism.• To follow suggested clinical management principles in relation to prenatal test counselling.Ethical issues
Clinicians face a dilemma following a high-risk NIPT result in the setting of normal ultrasound. Awaiting long-term culture or amniocentesis delays potential termination of pregnancy.
Sex chromosome ...
Source: The Obstetrician and Gynaecologist - November 29, 2022 Category: OBGYN Authors: Kelly Reilly,
Samantha Doyle,
Susan J Hamilton,
Mark D Kilby,
Fionnuala Mone Tags: Review Source Type: research
Thromboprophylaxis in gynaecology: a review of current evidence
AbstractKey content
Thromboembolism is a major cause of preventable morbidity and mortality. Hospital acquired thrombosis (HAT) accounts for 50 –60% of all thromboembolic events.
As well as effects on patient safety, there are considerable cost implications to both prophylaxis and treatment.
While guidance exists on thromboprophylaxis for patients in obstetrics and those undergoing general surgery, there is paucity of guidance relating to gynaecological practice.
Increasing prevalence of risk factors and multimorbidity is paralleled by higher risk of thromboembolic events.
Gynaecological surgery presents some unique risk...
Source: The Obstetrician and Gynaecologist - November 28, 2022 Category: OBGYN Authors: Divya Nambiar,
Jecko Thachil,
Wai Yoong,
Deepa Balachandran Nair Tags: Review Source Type: research
Manuscript title: Pitfalls of prenatal diagnosis associated with mosaicism
Discussion of the limitations and implications is essential and referral to clinical genetics may be warranted.Learning objectives• To understand the embryological causes for and types of fetal placental mosaicism.• To appreciate underlying principles in NIPT and genomic testing strategies in relation to mosaicism.• To follow suggested clinical management principles in relation to prenatal test counselling.Ethical issues
Clinicians face a dilemma following a high-risk NIPT result in the setting of normal ultrasound. Awaiting long-term culture or amniocentesis delays potential termination of pregnancy.
Sex chromosome ...
Source: The Obstetrician and Gynaecologist - November 28, 2022 Category: OBGYN Authors: Kelly Reilly,
Samantha Doyle,
Susan J Hamilton,
Mark D Kilby,
Fionnuala Mone Tags: Review Source Type: research
Management of Bartholin's cyst and abscess
(Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - November 28, 2022 Category: OBGYN Authors: Ayesha Bati ‐Paracha,
Mona Sharma Tags: Tips and Techniques Source Type: research
Management of term breech presentation
Key content
While most breech babies are delivered by caesarean section, a small number are born vaginally.
Detailed counselling and an accoucher skilled in vaginal breech birth (VBB) are essential for offering the modality.
External cephalic version (ECV) is safe, acceptable to most women, has few contraindications and increases vaginal birth rates.
Undiagnosed term breech presentation can largely be prevented by routine third-trimester ultrasound.
Research is needed to evaluate the efficacy of VBB simulation training in clinical practice.Learning objectives
To understand the evidence base around breech presentation...
Source: The Obstetrician and Gynaecologist - November 25, 2022 Category: OBGYN Authors: Paul Timmons,
Victoria Wallis,
Shawn Walker,
Djavid Alleemudder Tags: Review Source Type: research
Premenstrual disorders including premenstrual syndrome and premenstrual dysphoric disorder
AbstractKey content
The spectrum of premenstrual disorders is related to hormonal changes in the menstrual cycle and are experienced by nearly 40% of women.
Approximately 3 –8% of women are affected by severe premenstrual syndrome, including premenstrual dysphoric disorder (PMDD); a chronic, debilitating disorder with severe emotional and physical symptoms and functional impairment.
PMDD significantly affects women's quality of life; recent evidence suggests that 86% of patients have considered suicide, with 30% having attempted suicide at least once.
In 2019, PMDD was added to the International Statistical Classificatio...
Source: The Obstetrician and Gynaecologist - November 14, 2022 Category: OBGYN Authors: Nidhi Goswami,
Kalpana Upadhyay,
Paula Briggs,
Elizabeth Osborn,
Nick Panay Tags: Review Source Type: research
