Paraneoplastic syndrome associated with gynaecological malignancy: a review of the evidence
AbstractKey Content: Paraneoplastic syndrome (PNS) is a clinical manifestation of both benign and malignant tumours. Symptoms are not attributable to direct organ involvement of the cancer nor as a therapeutic adverse effect; instead, they are a result of hormones, cytokines or growth factors released by the tumour, or an immunological response. Paraneoplastic syndromes can affect any body system, so can cause myriad potential symptoms. These clinical manifestations often pre-date those of the underlying disease process. The incidence of PNS attributable to gynaecological tumours is increasing, resulting in considerable mo...
Source: The Obstetrician and Gynaecologist - March 12, 2022 Category: OBGYN Authors: Adam Brown, Sarah McKenna, Deborah Forbes, Ian Harley Tags: REVIEWS Source Type: research

The diagnosis and management of fetal cardiac arrhythmias
AbstractKey content Fetal cardiac arrhythmias are relatively common and account for up to 20% of referrals to fetal cardiologists. Arrhythmias may occur because of structural abnormalities of the fetal heart, or because of abnormal functioning of the cardiac conduction system in an otherwise structurally normal heart. Arrythmias may be diagnosed using ultrasound and M-mode and Doppler echocardiography Transplacental therapy for tachyarrythmias has been one of the success stories of fetal cardiology, and good outcomes can be expected in the absence of hydrops. Congenital heart block is most commonly caused by the transplace...
Source: The Obstetrician and Gynaecologist - March 12, 2022 Category: OBGYN Authors: Daniel Stott, Pranav P Pandya, George Attilakos, Janet Lang, Joanne Wolfenden, Robert Yates Tags: REVIEWS Source Type: research

Domestic violence: an invisible pandemic
(Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - March 9, 2022 Category: OBGYN Authors: Teesta Dey, Ranee Thakar Tags: Commentary Source Type: research

Impact of the intrauterine environment on future reproductive and metabolic health
Key content As survival of babies born following high-risk pregnancies continues to increase globally, understanding the long-term impacts of suboptimal intrauterine environments on future health becomes increasingly important. The intrauterine environment is a key influence on later metabolic health, particularly the tendency to later-life obesity and dyslipidaemia. Recent evidence shows that female reproductive function is also highly sensitive to the influence of the early life environment. Various suboptimal intrauterine environments are linked to adverse reproductive and metabolic outcomes, including maternal obesity,...
Source: The Obstetrician and Gynaecologist - March 8, 2022 Category: OBGYN Authors: Suzanna Dunkerton, Catherine Aiken Tags: Review Source Type: research

Re: The role of antenatal corticosteroids in improving neonatal outcomes
(Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - March 1, 2022 Category: OBGYN Authors: P. D. M. Pathiraja, Junaid Rafi Tags: Letters and emails Source Type: research

Oophorectomy or ovarian conservation at the time of hysterectomy for benign disease
AbstractKey content Bilateral salpingo-oophorectomy is indicated for patients with suspected or confirmed gynaecological malignancy. Risk reduction surgery is indicated in patients with a significant family history or a genetic predisposition to developing breast or ovarian cancer. Bilateral salpingectomy with ovarian conservation reduces the risk of ovarian cancer, whilst preserving ovarian function. Oophorectomy prior to the menopause is associated with increased all-cause mortality and significant menopause related morbidity. Conservative measures such as weight loss, family planning and lifestyle advice could reduce th...
Source: The Obstetrician and Gynaecologist - February 25, 2022 Category: OBGYN Authors: Victoria Asfour, Adam D Jakes, Jess McMicking, Wei Zian Szetho, Ahmad Sayasneh, Yasser Diab, Lawrence Mascarenhas, Janice Rymer Tags: REVIEWS Source Type: research

Domestic violence: an invisible pandemic
Abstract- (Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - February 24, 2022 Category: OBGYN Authors: Teesta Dey, Ranee Thakar Tags: COMMENTARY Source Type: research

Impact of the intrauterine environment on future reproductive and metabolic health
AbstractKey content: As survival of babies born following high-risk pregnancies continues to increase globally, understanding the long-term impacts of suboptimal intrauterine environments on future health becomes increasingly important. The intrauterine environment is a key influence on later metabolic health, particularly the tendency to later-life obesity and dyslipidaemia. Recent evidence shows that female reproductive function is also highly sensitive to the influence of the early life environment. Various suboptimal intrauterine environments are linked to adverse reproductive and metabolic outcomes, including maternal...
Source: The Obstetrician and Gynaecologist - February 22, 2022 Category: OBGYN Authors: Suzanna Dunkerton, Catherine Aiken Tags: REVIEWS Source Type: research

www.eatingdisordersandpregnancy.co.uk
(Source: The Obstetrician and Gynaecologist)
Source: The Obstetrician and Gynaecologist - February 3, 2022 Category: OBGYN Tags: WEBSITE REVIEW Source Type: research

Accessory cavitated uterine malformations (ACUMs): an unfamiliar cause of dysmenorrhoea
Key Content Accessory cavitated uterine malformations (ACUMs) are isolated cavitated lesions within the lateral aspect of the myometrium, inferior to the attachment of the round ligament. They are a rare M üllerian anomaly and are increasingly recognised as a cause for severe dysmenorrhoea and pelvic pain. ACUMs can be diagnosed with ultrasound and magnetic resonance imaging, where they appear as well-defined lesions with a central cavity containing haemorrhagic content, surrounded by a myometrial m antle. On histological examination, the cavity is lined by functional endometrial glands and stroma. Recognised treatmen...
Source: The Obstetrician and Gynaecologist - January 31, 2022 Category: OBGYN Authors: Thulasi Setty, Joel Naftalin, Davor Jurkovic Tags: Review Source Type: research