Thromboprophylaxis in gynaecology: a review of current evidence
AbstractKey content
Thromboembolism is a major cause of preventable morbidity and mortality. Hospital acquired thrombosis (HAT) accounts for 50 –60% of all thromboembolic events.
As well as effects on patient safety, there are considerable cost implications to both prophylaxis and treatment.
While guidance exists on thromboprophylaxis for patients in obstetrics and those undergoing general surgery, there is paucity of guidance relating to gynaecological practice.
Increasing prevalence of risk factors and multimorbidity is paralleled by higher risk of thromboembolic events.
Gynaecological surgery presents some unique risk factors for thrombosis.Learning objectives
To understand the basic pathophysiology of thrombosis in relation to risk factors particularly relevant to gynaecology and pelvic surgery
To know the current evidence in key areas relevant to gynaecological practice: early pregnancy; day case surgery; minimally invasive gynaecological surgery; open and complex benign gynaecology and gynaecological oncology
To be aware of proposed guidance on risk assessment and prophylaxis in thrombosis as relevant to the gynaecologist based on current evidenceEthical issues
Problems with thromboprophylaxis in high-risk patients include noncompliance and refusing animal products/injections.
Clinicians may be reluctant to institute thromboprophylaxis, most times because of the possible risks of bleeding.
Source: The Obstetrician and Gynaecologist - Category: OBGYN Authors: Divya Nambiar,
Jecko Thachil,
Wai Yoong,
Deepa Balachandran Nair Tags: Review Source Type: research
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