Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Synthesis of psychotropic alkaloids from < em > Galbulimima < /em >
Tetrahedron. 2022 Nov 5;126:133064. doi: 10.1016/j.tet.2022.133064. Epub 2022 Oct 5.ABSTRACTEfficient syntheses of valuable natural products open gateways from kind learning environments to wicked worlds, where long-term, interdisciplinary research questions can be asked and answered. In this Perspective, we discuss the Galbulimima (GB) alkaloids, metabolites of a rainforest canopy tree that exhibit potent but poorly understood effects in humans, including accounts of hallucination. Recent syntheses from our group have opened up GB alkaloid chemical space for investigation by way of new cross-coupling reactions and gram-sc...
Source: Tetrahedron - October 9, 2023 Category: Chemistry Authors: Stone Woo Eleanor M Landwehr Ryan A Shenvi Source Type: research

Evaluation of helicene-derived 2,2'-bipyridine < em > N- < /em > monoxide catalyst for the enantioselective propargylation of < em > N < /em > -acylhydrazones with allenyltrichlorosilane
This study represents the first example of the catalytic asymmetric propargylation of non-activated acylhydrazones.PMID:37790873 | PMC:PMC10545348 | DOI:10.1016/j.tet.2023.133496 (Source: Tetrahedron)
Source: Tetrahedron - October 4, 2023 Category: Chemistry Authors: Changgong Xu Phillip Nader Jonathan Xavier Burjor Captain Norito Takenaka Source Type: research

Evaluation of helicene-derived 2,2'-bipyridine < em > N- < /em > monoxide catalyst for the enantioselective propargylation of < em > N < /em > -acylhydrazones with allenyltrichlorosilane
This study represents the first example of the catalytic asymmetric propargylation of non-activated acylhydrazones.PMID:37790873 | PMC:PMC10545348 | DOI:10.1016/j.tet.2023.133496 (Source: Tetrahedron)
Source: Tetrahedron - October 4, 2023 Category: Chemistry Authors: Changgong Xu Phillip Nader Jonathan Xavier Burjor Captain Norito Takenaka Source Type: research