Seminars in Respiratory and Critical Care Medicine 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Imaging of Lung Disease Associated with Connective Tissue Disease
Semin Respir Crit Care Med DOI: 10.1055/s-0042-1755566There is a well-known association between the connective tissue disorders (CTDs) and lung disease. In addition to interstitial lung disease, the CTDs may affect the air spaces and pulmonary vasculature. Imaging tests are important not only in diagnosis but also in management of these complex disorders. In the present review, key aspects of the imaging of CTD-reated diseases are discussed. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: ...
Source: Seminars in Respiratory and Critical Care Medicine - October 28, 2022 Category: Respiratory Medicine Authors: Bartlett, Emily C. Renzoni, Elizabeth A. Sivarasan, Nishanth Desai, Sujal R. Tags: Review Article Source Type: research
High-Resolution Computed Tomography of Cystic Lung Disease
Semin Respir Crit Care Med DOI: 10.1055/s-0042-1755565The cystic lung diseases (CLD) are characterized by the presence of multiple, thin-walled, air-filled spaces in the pulmonary parenchyma. Cyst formation may occur with congenital, autoimmune, inflammatory, infectious, or neoplastic processes. Recognition of cyst mimics such as emphysema and bronchiectasis is important to prevent diagnostic confusion and unnecessary evaluation. Chest CT can be diagnostic or may guide the workup based on cyst number, distribution, morphology, and associated lung, and extrapulmonary findings. Diffuse CLD (DCLDs) are often considered those ...
Source: Seminars in Respiratory and Critical Care Medicine - October 17, 2022 Category: Respiratory Medicine Authors: Kusmirek, Joanna E. Meyer, Cristopher A. Tags: Review Article Source Type: research
Chronic Obstructive Pulmonary Disease and Small Airways Diseases
Semin Respir Crit Care Med DOI: 10.1055/s-0042-1755567The small airways are a common target of injury within the lungs and may be affected by a wide variety of inhaled, systemic, and other disorders. Imaging is critical in the detection and diagnosis of small airways disease since significant injury may occur prior to pulmonary function tests showing abnormalities. The goal of this article is to describe the typical imaging findings and patterns of small airways diseases. An approach which divides the imaging appearances into four categories (tree-in-bud opacities, poorly defined centrilobular nodules, mosaic attenuation, ...
Source: Seminars in Respiratory and Critical Care Medicine - October 17, 2022 Category: Respiratory Medicine Authors: Elicker, Brett M. Tags: Review Article Source Type: research
Structural Inequities in Medicine that Contribute to Racial Inequities in Asthma Care
Semin Respir Crit Care Med 2022; 43: 752-762 DOI: 10.1055/s-0042-1756491Structural inequities in medicine have been present for centuries in the United States, but only recently are these being recognized as contributors to racial inequities in asthma care and asthma outcomes. This chapter provides a systematic review of structural factors such as racial bias in spirometry algorithms, the history of systemic racism in medicine, workforce/pipeline limitations to the presence of underrepresented minority health care providers, bias in research funding awards, and strategies to solve these problems. [...] Thieme Medical Publi...
Source: Seminars in Respiratory and Critical Care Medicine - October 11, 2022 Category: Respiratory Medicine Authors: Okelo, Sande O. Tags: Review Article Source Type: research
Phenotyping, Precision Medicine, and Asthma
Semin Respir Crit Care Med 2022; 43: 739-751 DOI: 10.1055/s-0042-1750130The traditional one-size-fits all approach based on asthma severity is archaic. Asthma is a heterogenous syndrome rather than a single disease entity. Studies evaluating observable characteristics called phenotypes have elucidated this heterogeneity. Asthma clusters demonstrate overlapping features, are generally stable over time and are reproducible. What the identification of clusters may have failed to do, is move the needle of precision medicine meaningfully in asthma. This may be related to the lack of a straightforward and clinically meaningful w...
Source: Seminars in Respiratory and Critical Care Medicine - October 11, 2022 Category: Respiratory Medicine Authors: Mohan, Arjun Lugogo, Njira L. Tags: Review Article Source Type: research
Racial Inequities in Asthma Care
This study provides a systematic review of racial asthma care inequities in asthma epidemiology, clinical assessment, medication prescription, and asthma specialist referral practices. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Seminars in Respiratory and Critical Care Medicine)
Source: Seminars in Respiratory and Critical Care Medicine - October 11, 2022 Category: Respiratory Medicine Authors: Okelo, Sande O. Tags: Review Article Source Type: research
Current Biologics in Asthma Treatment
Semin Respir Crit Care Med 2022; 43: 627-634 DOI: 10.1055/s-0042-1753486Uncontrolled asthma and/or severe asthma causes significant impairments in quality of life and is often a huge health care burden. Monoclonal antibodies have been an important addition to the therapeutic management of patients with moderate to severe asthma who do not respond to conventional asthma management. Currently the majority of Food and Drug Administration (FDA) approved biologics target T2 high inflammation. However, with the expanding knowledge of asthma pathogenesis, novel therapeutics targeting T2 low inflammation are in development. In thi...
Source: Seminars in Respiratory and Critical Care Medicine - October 11, 2022 Category: Respiratory Medicine Authors: Imanirad, Donya Tabatabaian, Farnaz Tags: Review Article Source Type: research
Imaging of Occupational and Environmental Lung Disease
Semin Respir Crit Care Med DOI: 10.1055/s-0042-1755568The respiratory tract is continuously exposed to and filters toxins from the home and work environments. Certain occupations and environmental exposures can cause unique injuries to the upper and lower respiratory system. Despite increasing federal regulations in the workplace, occupation-associated lung disease is still a major cause of lung disease and disability and continues to evolve with changes in industry, regulation, and new emerging exposures and toxins. Establishing a diagnosis can be difficult, often due to long latency between exposure and clinical disease,...
Source: Seminars in Respiratory and Critical Care Medicine - October 1, 2022 Category: Respiratory Medicine Authors: Carroll, Melissa B. Kanne, Jeffrey P. Tags: Review Article Source Type: research
Artificial Intelligence in Lung Imaging
Semin Respir Crit Care Med DOI: 10.1055/s-0042-1755571Recently, interest and advances in artificial intelligence (AI) including deep learning for medical images have surged. As imaging plays a major role in the assessment of pulmonary diseases, various AI algorithms have been developed for chest imaging. Some of these have been approved by governments and are now commercially available in the marketplace. In the field of chest radiology, there are various tasks and purposes that are suitable for AI: initial evaluation/triage of certain diseases, detection and diagnosis, quantitative assessment of disease severity and monit...
Source: Seminars in Respiratory and Critical Care Medicine - September 29, 2022 Category: Respiratory Medicine Authors: Choe, Jooae Lee, Sang Min Hwang, Hye Jeon Lee, Sang Min Yun, Jihye Kim, Namkug Seo, Joon Beom Tags: Review Article Source Type: research
Nonmalignant Pleural Effusions
Semin Respir Crit Care Med 2022; 43: 570-582 DOI: 10.1055/s-0042-1748186Although the potential causes of nonmalignant pleural effusions are many, the management of a few, including complicated pleural infections and refractory heart failure and hepatic hydrothoraces, can be challenging and requires the assistance of interventional pulmonologists. A pragmatic approach to complicated parapneumonic effusions or empyemas is the insertion of a small-bore chest tube (e.g., 14–16 Fr) through which fibrinolytics (e.g., urokinase and alteplase) and DNase are administered in combination. Therapeutic thoracenteses are usually reser...
Source: Seminars in Respiratory and Critical Care Medicine - September 14, 2022 Category: Respiratory Medicine Authors: Porcel, Jos é M. Tags: Review Article Source Type: research
Mediastinal Staging with Endobronchial Ultrasound in Early-Stage Non —Small Cell Lung Cancer: Is It Necessary?
Semin Respir Crit Care Med 2022; 43: 503-511 DOI: 10.1055/s-0042-1748189Herein we examine the need for minimally invasive mediastinal staging for patients with early-stage non—small cell lung cancer (NSCLC) using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Early NSCLC, stages 1 and 2, has a 5-year survival rate between 53 and 92%, whereas stages 3 and 4 have a 5-year survival of 36% and below. With more favorable outcomes in earlier stages, greater emphasis has been placed on identifying lung cancer earlier in its disease process. Accurate staging is crucial as it dictates both prognosis...
Source: Seminars in Respiratory and Critical Care Medicine - September 14, 2022 Category: Respiratory Medicine Authors: Husta, Bryan C. Kalchiem-Dekel, Or Beattie, Jason A. Yasufuku, Kazuhiro Tags: Review Article Source Type: research
Therapeutic Bronchoscopy for Lung Nodules: Where Are We Now?
Semin Respir Crit Care Med 2022; 43: 480-491 DOI: 10.1055/s-0042-1749368Lobar resection has been the established standard of care for peripheral early-stage non—small cell lung cancer (NSCLC). Over the last few years, surgical lung sparing approach (sublobar resection [SLR]) has been compared with lobar resection in T1N0 NSCLC. Three nonsurgical options are available in those patients who have a prohibitive surgical risk, and those who refuse surgery: stereotactic body radiotherapy (SBRT), percutaneous ablation, and bronchoscopic ablation. Local ablation involves placement of a probe into a tumor, and subsequent applicat...
Source: Seminars in Respiratory and Critical Care Medicine - September 14, 2022 Category: Respiratory Medicine Authors: Folch, Erik Guo, Yanglin Senitko, Michal Tags: Review Article Source Type: research
Nodules, Navigation, Robotic Bronchoscopy, and Real-Time Imaging
Semin Respir Crit Care Med 2022; 43: 473-479 DOI: 10.1055/s-0042-1747930The process of detection, diagnosis, and management of lung nodules is complex due to the heterogeneity of lung pathology and a relatively low malignancy rate. Technological advances in bronchoscopy have led to less-invasive diagnostic procedures and advances in imaging technology have helped to improve nodule localization and biopsy confirmation. Future research is required to determine which modality or combination of complimentary modalities is best suited for safe, accurate, and cost-effective management of lung nodules. [...] Thieme Medical Publis...
Source: Seminars in Respiratory and Critical Care Medicine - September 14, 2022 Category: Respiratory Medicine Authors: Manley, Christopher J. Pritchett, Michael A. Tags: Review Article Source Type: research
Interventional Pulmonary
Semin Respir Crit Care Med 2022; 43: 471-472 DOI: 10.1055/s-0042-1753472 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Full text (Source: Seminars in Respiratory and Critical Care Medicine)
Source: Seminars in Respiratory and Critical Care Medicine - September 14, 2022 Category: Respiratory Medicine Authors: Oh, Scott S. Folch, Erik Herth, Felix J. F. Tags: Preface Source Type: research
Monitoring Lung Injury Severity and Ventilation Intensity during Mechanical Ventilation
Semin Respir Crit Care Med 2022; 43: 346-368 DOI: 10.1055/s-0042-1748917Acute respiratory distress syndrome (ARDS) is a severe form of respiratory failure burden by high hospital mortality. No specific pharmacologic treatment is currently available and its ventilatory management is a key strategy to allow reparative and regenerative lung tissue processes. Unfortunately, a poor management of mechanical ventilation can induce ventilation induced lung injury (VILI) caused by physical and biological forces which are at play. Different parameters have been described over the years to assess lung injury severity and facilitate o...
Source: Seminars in Respiratory and Critical Care Medicine - July 27, 2022 Category: Respiratory Medicine Authors: Rezoagli, Emanuele Laffey, John G. Bellani, Giacomo Tags: Review Article Source Type: research
