FDA Approves Naloxone Nasal Spray for Over-the-Counter Sale
The U.S. Food and Drug Administration (FDA) yesterdayapproved Narcan (naloxone) 4 mg hydrochloride nasal spray for purchase without a prescription. Narcan rapidly reverses the effects of an opioid overdose.“Naloxone is a critical tool in addressing opioid overdoses, and today’s approval underscores the extensive efforts the agency has undertaken to combat the overdose crisis,” Patrizia Cavazzoni, M.D., director of the FDA’s Center for Drug Evaluation and Research, said in an FDA news release.The FDA ’s action “paves the way” for Narcan to be sold in drugstores, supermarkets, convenience stores, gas stations, ...
Source: Psychiatr News - March 30, 2023 Category: Psychiatry Tags: APA Emergent BioSolutions FDA Food and Drug Administration naloxone narcan opioid overdose OTC over the counter medication Robert Califf substance use disorder Source Type: research
Hospital Incentive Program Found to Increase Buprenorphine Prescriptions for Patients With OUD
Pennsylvania patients with opioid use disorder (OUD) were more likely to receive a prescription for buprenorphine within 30 days of a visit to the emergency department (ED) if they were seen at a hospital participating in the state ’s Opioid Hospital Quality Improvement Program than those seen at a hospital that did not participate in this program. These findings are described in arecent report inJAMA Health Forum.“With surging rates of opioid overdose deaths, ED encounters present a crucial opportunity to engage patients with OUD treatment,” wrote Keisha T. Solomon, Ph.D., of Howard University and colleagues. “The...
Source: Psychiatr News - March 29, 2023 Category: Psychiatry Tags: buprenorphine emergency department hospital incentives JAMA Health Forum medication for OUD MOUD opioid use Pennsylvania substance use disorder Source Type: research
Experts Call for Consistent Screening of Food Insecurity Among Adolescents
It is well established that adolescents experiencing food insecurity (inconsistent access to enough safe and affordable food to live an active, healthy life) are at greater risk of physical and mental problems. In aViewpoint article published yesterday in JAMA Pediatrics, Kaitlyn Harper, Ph.D., M.Sc., M.A., of Johns Hopkins Bloomberg School of Public Health and Hilary Seligman, M.D., M.A.S., of the University of California, San Francisco (UCSF), describe the need to integrate an accurate and reliable screening tool to assess food insecurity into clinical settings.“TheBiden-Harris national strategic plan emphasizes the im...
Source: Psychiatr News - March 28, 2023 Category: Psychiatry Tags: adolescents depression food insecurity JAMA Pediatrics morbidity risky health behaviors screening viewpoint youth Source Type: research
Attention Bias Modification Treatment Found Effective for Social Anxiety Disorder
People with social anxiety disorder may benefit from an intervention that trains them to focus their attention on neutral facial expressions more than negative ones, according to areport inAJP in Advance. In a clinical trial, participants with social anxiety disorder who received 10 sessions of an attention bias modification treatment over 12 weeks experienced similar symptom improvements as those who received 12 weeks of escitalopram —a first-line treatment for the disorder.“Social anxiety disorder involves chronic fear and avoidance of scrutiny,” wrote Gal Arad, M.A., of Tel Aviv University, Daniel S. Pine, M.D., o...
Source: Psychiatr News - March 27, 2023 Category: Psychiatry Tags: American Journal of Psychiatry eye-tracking intervention facial expression gaze-contingent music reward therapy scowl Social anxiety disorder Source Type: research
Sleep Apnea Linked to Increased Risk of Suicide Attempts
People who are diagnosed with sleep apnea may have an increased risk of dying by suicide, astudy in theJournal of Psychiatric Research has found. Sleep apnea is a potentially serious disorder in which breathing repeatedly stops and starts during sleep.Che-Sheng Chu, M.D., of Kaohsiung Veterans General Hospital in Kaohsiung City, Taiwan, and colleagues examined data from the Taiwan National Health Insurance Research Database. The researchers selected 7,095 adults aged 20 years or older who had been diagnosed with sleep apnea between 1998 and 2010 and 28,380 adults without sleep apnea who were matched based on their age, sex...
Source: Psychiatr News - March 24, 2023 Category: Psychiatry Tags: depression diabetes disrupted sleep Journal of Psychiatric Research repeat suicide attempts sleep apnea Source Type: research
Antipsychotic Polypharmacy at Higher Doses Does Not Increase Hospitalization Risk, Study Finds
Patients with schizophrenia appear to be at a lower risk of hospitalization for physical health issues when taking high doses of two or more antipsychotic medications concurrently (polypharmacy) than when taking just one antipsychotic medication (monotherapy) at the same dose, according to astudy published yesterday inAJP in Advance.“When patients were treated with high-dose antipsychotic monotherapy …, they had approximately a 20% higher risk of severe cardiovascular outcomes leading to hospitalization compared with periods when the same patients were treated with corresponding high-dose combination therapy,” wrote ...
Source: Psychiatr News - March 23, 2023 Category: Psychiatry Tags: AJP antipsychotics cardiovascular hospitalization monotherapy nonpsychiatric hospitalization polypharmacy schizophrenia Source Type: research
Parents May Underestimate Frequency of Mental Health Concerns Among College Students
College students are far more likely to report having experienced an eating disorder, depression, or suicidal ideation compared with what parents report knowing about their children ’s experiences with mental illness, according to aUnitedHealthcare report published today.“It may not be surprising that some students and parents have different perceptions of the college experience, but this report demonstrates the need to create environments for ongoing meaningful conversations with these emerging adults,” said Donald Tavakoli, M.D., national medical director for behavioral health with UnitedHealthcare, in anews releas...
Source: Psychiatr News - March 22, 2023 Category: Psychiatry Tags: college cost depression eating disorders insurance mental health parents substance use disorders SUD suicidal ideation suicidal intent UnitedHealthcare Source Type: research
Breast Cancer in Women With Severe Mental Illness Often Undertreated, Review Suggests
Women with severe mental illness (SMI) —such as schizophrenia, bipolar disorder, or major depression—are less likely to receive recommended treatment for breast cancer than those without SMI, according to areport inPsycho-Oncology.Prior studies suggest that death from breast cancer is higher among patients with preexisting SMI compared with those without mental illness. Such higher death rates may be the result of reduced access to early cancer screening; delays in seeking cancer care; and/or a lack of collaboration between psychiatrists, primary care physicians, and oncologists, wrote Steve Kisely, M.D., Ph.D., of the...
Source: Psychiatr News - March 21, 2023 Category: Psychiatry Tags: bipolar disorder breast cancer chemotherapy depression diagnosis hormone therapy psycho-oncology radiation schizophrenia severe mental illness SMI surgery treatment Source Type: research
Postoperative Delirium Associated With Accelerated Cognitive Decline, Study Finds
Older adults who develop delirium after a surgery may experience faster cognitive decline than those who do not develop post-surgery delirium, suggestsa report inJAMA Internal Medicine. The findings are based on cognitive data collected up to six years after the participants ’ elective surgeries.“Delirium is recognized as a common and serious disorder and represents the most frequent postoperative complication in older adults,” Zachary J. Kunicki, Ph.D., M.S., M.P.H., of Brown University and colleagues wrote. “With growing recognition of the association of delirium with a higher risk for long-term cognitive decline...
Source: Psychiatr News - March 20, 2023 Category: Psychiatry Tags: attention cognitive decline delirium JAMA Internal Medicine language memory postoperative SAGES Successful Aging after Elective Surgery Source Type: research
1 in 5 Deaths by Suicide Related to Intimate Partner Problems
One in five deaths by suicide is related to problems with current or former intimate partners such as divorce, separation, romantic breakups, arguments, jealousy, conflicts, and intimate partner violence, astudy in theAmerican Journal of Preventive Medicine has found.Ayana Stanley, Dr.P.H., of the Centers for Disease Control and Prevention Division of Violence Prevention and colleagues analyzed data from the National Violent Death Reporting System for 402,391 adults who died by suicide between 2003 and 2020. They compared the circumstances leading up to suicide deaths related to intimate partner problems with suicide death...
Source: Psychiatr News - March 17, 2023 Category: Psychiatry Tags: American Journal of Preventive Medicine divorce intimate partner violence jealousy relationship problems separation suicide Source Type: research
Certain Patients With OUD Remain at Risk of Overdose After Entering Treatment
Patients who enrolled in a trial of medication treatment for opioid use disorder (OUD) who did not start or complete their assigned medication were at greater risk of experiencing an overdose than those who took their medication, according to astudy published inThe American Journal of Psychiatry.“A substantial body of evidence has shown that treatment with medication for opioid use disorder (MOUD) can decrease both overdose risk and all-cause mortality among people with opioid use disorder,” wrote Laura Brandt, Ph.D., of City College of New York and colleagues. “The aim of this study was to estimate the risk of overd...
Source: Psychiatr News - March 16, 2023 Category: Psychiatry Tags: American Journal of Psychiatry medication for OUD MOUD opioid use disorder overdose Source Type: research
California Insurance Law Linked to Increase in Gender-Affirming Surgery
Individuals with gender dysphoria who lived in California were significantly more likely to undergo gender-affirming surgery following the 2013 implementation of a state law prohibiting insurance discrimination against gender-affirming care compared with those living in Arizona and Washington, where no such law exists. That was the finding from astudy of 25,252 transgender and gender-diverse patients in California, Washington, and Arizona that was published yesterday inJAMA.The increase appeared significant among patients with private insurance or Medicaid, but not patients paying out of pocket.“The findings suggest that...
Source: Psychiatr News - March 15, 2023 Category: Psychiatry Tags: Arizona California gender-affirming care gender-affirming surgery gender-diverse JAMA legislation transgender Washington Source Type: research
COVID-19 Stress During Pregnancy Associated With Worse Postpartum Outcomes
Experiencing high levels of stress during pregnancy is known to place mothers and their infants at risk of mental health problems. Areport published today inJAMA Network Open highlights some of the impact that worries about COVID-19 may have had on the mental health of women and their offspring.In a longitudinal study, Susanne Schweizer, Ph.D., of the University of Cambridge and colleagues found that “COVID-19–related stress was significantly associated with maternal postpartum distress, depression, and GAD [general anxiety disorder] as well as infant negative affectivity, even when controlling for COVID-19 risk report...
Source: Psychiatr News - March 14, 2023 Category: Psychiatry Tags: anxiety COVID-19 depression infant JAMA Network Open maternal health mothers negative affectivity pandemic positive affectivity postpartum distress pregnancy Source Type: research
Family Bereavement Program Offers Long-Term Protection Against Depression
Children who experience the death of a parent are known to be at an increased risk of depression and other internalizing problems later in life. Astudy in theJournal of the American Academy of Child& Adolescent Psychiatry has found that children who together with their families participated in a bereavement program within 2.5 years of the death were less likely to experience depression up to 15 years later.“The findings from this study have implications for future research on the prevention of depression,” wrote Irwin Sandler, Ph.D., of Arizona State University and colleagues.Sandler and colleagues enrolled 244 you...
Source: Psychiatr News - March 13, 2023 Category: Psychiatry Tags: adolescents anxiety children death depression family bereavement grief Journal of the Academy of Child & Adolescent Psychiatry positive parenting youth Source Type: research
Combined Motivational Interviewing, CBT Found to Increase Motivation in People With Schizophrenia
People with schizophrenia are known to experience motivational deficits (for example, defeatist beliefs and social withdrawal) that can hinder their ability to engage in social and occupational activities. Astudy published yesterday inThe American Journal of Psychiatry found that patients who participated in weekly group therapy sessions that combined motivational interviewing and cognitive-behavioral therapy (CBT) for three months experienced greater improvements in motivation and pleasure than those who did not receive the combined therapy.“While there have been advances in pharmacological interventions for positive sy...
Source: Psychiatr News - March 10, 2023 Category: Psychiatry Tags: American Journal of Psychiatry cognitive-behavioral therapy function group therapy mindfulness motivation motivational interviewing negative symptoms schizophrenia Source Type: research
