FDA Approves First Oral Medication for Postpartum Depression
The U.S. Food and Drug Administration (FDA) on Fridayapproved Zurzuvae (zuranolone), the first oral medication for the treatment of postpartum depression in adults. Zuranolone acts on similar receptors in the brain as the intravenous medication brexanolone, which was the first postpartum depression medication to receive FDA approvalin 2019.“As a perinatal psychiatrist, I see the devastating impact [postpartum depression] has on mothers, particularly on the important mother-infant bond and long-term child development,” Kristina Deligiannidis, M.D., principal investigator of the Zurzuvae clinical program, said in apress ...
Source: Psychiatr News - August 7, 2023 Category: Psychiatry Tags: American Journal of Psychiatry Jennifer Payne Kristina Deligiannidis mother-infant bond postpartum depression SAGE zuranolone Zurzuvae Source Type: research
Suicide Most Common Cause of Death in People With Schizophrenia, Study Finds
Suicide is the most common cause of death in patients who have schizophrenia spectrum disorders, astudy inSchizophrenia Bulletin has found.Marie Stefanie Kejser Starzer, M.D., of Copenhagen University Hospital and colleagues analyzed data from the OPUS I study, a randomized controlled trial of 578 patients experiencing their first episode of psychosis. Patients enrolled in the study between January 1, 1998, and December 31, 2000. When the patients enrolled, they were between 18 and 45 years old; had received first-time treatment for a diagnosis of schizophrenia, schizotypal disorder, delusional disorder, acute or transient...
Source: Psychiatr News - August 4, 2023 Category: Psychiatry Tags: accidents death disease first-episode psychosis schizophrenia Schizophrenia Bulletin substance use suicide suicide prevention Source Type: research
Trained Officers Using Current Field Sobriety Tests May Misclassify Cannabis-Impaired Drivers
Current field sobriety tests administered by trained law enforcement officers may not be enough to identify drivers who are driving under the influence of cannabis, according to areport published yesterday inJAMA Psychiatry.“Road safety is a critical issue in an era of increasing cannabis legalization,” wrote Thomas D. Marcotte, Ph.D., of the Center for Medicinal Cannabis Research at the University of California, San Diego, and colleagues. “In the field, impairment is determined via observation of driving behavio r (i.e., vehicle in motion), driver interviews, and field sobriety tests …, which examine abilities, su...
Source: Psychiatr News - August 3, 2023 Category: Psychiatry Tags: cannabis impairment driving simulation driving under the influence DUI law enforcement sobriety test Source Type: research
NIDA, NIMH Directors Describe Promise, Challenges Associated With Psychedelics Research
The research challenges associated with the use of psychedelics to safely treat mental illness and substance use disorders are enormous —but so too is the promise, wrote Nora Volkow, M.D., director of the National Institute on Drug Abuse (NIDA); Joshua Gordon, M.D., director of the National Institute on Mental Health (NIMH); and Eric Wargo, Ph.D., a science writer with NIDA, in aViewpoint article inJAMA Psychiatry.“Although existing pharmacologic treatments such as antidepressants and medications for opioid use disorder are valuable for many people with these conditions, a large proportion are not helped by those treat...
Source: Psychiatr News - August 2, 2023 Category: Psychiatry Tags: contextual factors JAMA Psychiatry Joshua Gordon NIDA NIMH Nora Volkow placebo psychedelics research subjective experience Source Type: research
Gun Suicides Reach Record High in 2022, Provisional Data Show
The overall rate of suicide by guns in the United States increased 1.6% between 2021 and 2022, reaching an all-time high, according to provisional data from the Centers for Disease Control and Prevention (CDC). The data wereanalyzed by researchers at the John Hopkins Center for Gun Violence Solutions.“The provisional data show that the American epidemic of gun violence persists,” Ari Davis, M.P.P., a policy advisor with the center at Johns Hopkins, said in a news release. “[G]un suicides continue to take the lives of elderly White men at high rates and increasingly the lives of Black teens .”Davis and colleagues an...
Source: Psychiatr News - August 1, 2023 Category: Psychiatry Tags: Black teens CDC elderly men gun deaths gun homicide gun suicide Johns Hopkins Center for Violence Solutions provisional data Source Type: research
More Youth Drive Under the Influence of Cannabis Than Alcohol
Nearly a quarter of drivers between the ages of 16 and 20 years who have used cannabis in the past year have driven under the influence of the drug, astudy inAddictive Behaviors has found. Overall, more people in this age group reported driving under the influence of cannabis than under the influence of alcohol.Christopher P. Salas-Wright, Ph.D., M.S.W., M.A., of Boston College and colleagues examined data from 12,863 drivers aged 16 to 20 years who participated in the 2020 and 2021 National Survey on Drug Use and Health.Overall, 6.27% of the participants reported driving under the influence of cannabis and 2.63% reported ...
Source: Psychiatr News - July 31, 2023 Category: Psychiatry Tags: Addictive Behaviors alcohol cannabis driving under the influence DUI National Survey on Drug Use and Health prevention teens young adults youth Source Type: research
Urine Drug Screens as Part of OUD Treatment Can Be Successfully Managed Via Telehealth
Urine drug screening of people in treatment for opioid use disorder (OUD) is feasible and reliable via telehealth, according to a studypublished today inJAMA Health Forum.“This cohort study’s findings … are consistent with the premise that long-standing and stringent requirements (e.g., requiring in-person visits, frequent drug testing) for being prescribed buprenorphine for OUD can be relaxed without jeopardizing the quality or safety of care for many patients ,” wrote Arthur Robin Williams, M.D., M.B.E., of Columbia University and colleagues. Williams is also chief medical officer of Ophelia, a telehealth-based O...
Source: Psychiatr News - July 28, 2023 Category: Psychiatry Tags: Arthur Robin Williams buprenorphine Ophelia opioid use disorder OUD treatment telehealth urine drug screening urine test Source Type: research
Dementia Results in Nearly 1.4 Million Emergency Visits Annually, Study Finds
Patients with Alzheimer ’s disease and related dementias (ADRD) account for nearly 7% of all annual emergency department visits by individuals age 65 and older, according to areport published this week inJAMA Neurology.“Emergency departments are often not the right place to manage these behaviors,” Lauren Gerlach, D.O., M.S., of the University of Michigan Medical School, said in anews release. “We really need to do better to support caregivers so there are options other than seeking emergency care.”Gerlach and colleagues analyzed data on emergency department visits by adults aged 65 and older from the 2016-2019 N...
Source: Psychiatr News - July 27, 2023 Category: Psychiatry Tags: accidents Alzheimer ' s disease antipsychotics behavioral issues dementia emergency department JAMA Neurology urinary tract infections Source Type: research
Postpartum Depression Pill Zuralonone Shows Promise in Women With Severe Symptoms
Women with severe postpartum depression may experience improvements within a few days of taking the oral medication zuranolone (a neuroactive steroid), suggests areport published today inThe American Journal of Psychiatry. These improvements continued even after the women stopped the 14-day medication regimen.The study was funded by Sage Therapeutics and Biogen, which are involved in the development of the medication.Postpartum depression affects an estimated 17% of women worldwide, according to Kristina M. Deligiannidis, M.D., of Zucker Hillside Hospital and colleagues. This disorder can lead to multiple challenges for mo...
Source: Psychiatr News - July 26, 2023 Category: Psychiatry Tags: Biogen FDA HAM-A HAM-D major depressive episode postpartum depression SAGE side effects Source Type: research
Levin to Step Down as CEO and Medical Director of APA in May 2024
APA CEO and Medical Director Saul Levin, M.D., M.P.A., has announced that he is resigning from the position effective May 31, 2024.In a statement to the APA membership, the Board of Trustees wrote, “Dr. Levin started his tenure as APA CEO and Medical Director in July of 2013 and since then has led APA with vision and care. Under his leadership, APA has rebranded, moved its headquarters back into the District of Columbia, and purchased its office space. He oversaw the establishment of APA’s PsychPRO mental health registry and the build out of APA’s Communications, Government Relations, Policy, and Diversity and Health...
Source: Psychiatr News - July 25, 2023 Category: Psychiatry Tags: APA CEO APA Medical Director Levin resignation Maria Oquendo Petros Levounis Saul Levin World Psychiatric Association Source Type: research
Depression Over Adulthood May Increase Risk of Dementia
Adults diagnosed with depression are more likely to be subsequently diagnosed with dementia, according to astudy published today inJAMA Neurology.“This association persisted when the time elapsed from the [date of depression diagnosis] was greater than 20 years and when depression was diagnosed in early, middle, or late life,” wrote Holly Elser, M.D., Ph.D., of the University of Pennsylvania and colleagues. “Our results therefore sugges t that depression is not only an early symptom of dementia but also that depression is associated with an increase in dementia risk.”The researchers used Danish health registers to ...
Source: Psychiatr News - July 24, 2023 Category: Psychiatry Tags: adulthood antidepressant dementia depression JAMA Neurology risk of dementia treatment Source Type: research
More Than One-Third of Bereaved May Have Prolonged Grief Disorder
More than one-third of people who are grieving meet theDSM-5 criteria forprolonged grief disorder, astudy in the Journal of Affective Disordershas found. Yet the results suggest that most people who are bereaved feel that their grief is a normal response to loss regardless of how long they ’ve been grieving.“Although respondents’ views of the normalcy of their grief may be subject to bias, as in any other area of self-evaluation, it is useful to know how bereaved individuals themselves view their grief experiences,” wrote Kara Thieleman, Ph.D., of Arizona State University and colleagues. The researchers survey...
Source: Psychiatr News - July 21, 2023 Category: Psychiatry Tags: accidents bereavement DSM-5 homicide Journal of Affective Disorders overdose prolonged grief disorder relationships Source Type: research
Study Suggests Few Disruptions in Treatment for OUD During the Pandemic
Disruptions in health care services during the COVID-19 pandemic did not significantly reduce the ability of adults to remain in treatment for opioid use disorder (OUD), suggests areport published this week inPsychiatric Services. The authors believe that access to telehealth services was partially responsible for the continuation of care during this period.“Among a group of adults with commercial insurance or Medicare Advantage who had received opioid use disorder treatment before the COVID-19 pandemic, we observed minimal changes in outpatient and [medications for OUD] treatment utilization in the 2 years after pandemi...
Source: Psychiatr News - July 20, 2023 Category: Psychiatry Tags: COVID-19 in-person appointments medication for OUD opioid use disorder outpatient treatment pandemic Psychiatric Services telehealth Source Type: research
Mood Disorders in Parents May Increase Risk of Anxiety Disorders in Offspring
Children who have a parent with a mood disorder appear to be at an elevated risk of a several anxiety disorders, suggests areport in theJournal of the American Academy of Child and Adolescent Psychiatry. The findings, which were based on a meta-analysis of 35 studies, suggest that children may be particularly at risk for panic disorder.“Although we know that there is an overall increased risk for anxiety disorder in general among offspring of parents with mood disorders, little is understood about the risks of specific anxiety disorders and whether the risks differ between parental mood disorder subtypes,” wrote lead a...
Source: Psychiatr News - July 19, 2023 Category: Psychiatry Tags: anxiety disorder Journal of the American Academy of Child & Adolescent Psychiatry mood disorder parents phobias seasonal affective disorder Source Type: research
Donanemab Significantly Slows Progression of Alzheimer ’s Disease, Study Finds
The drug donanemab significantly slowed the clinical progression of Alzheimer ’s disease among patients with mild cognitive impairment or mild dementia, according to astudy published yesterday inJAMA.Donanemab is an antibody designed to target and remove beta-amyloid proteins that have clumped together to form plaques in the brain. It is manufactured by Eli Lilly and Company, which stated in anews release that it has submitted the drug for U.S. Food and Drug Administration (FDA) approval and expects regulatory action by the end of this year. Eli Lilly funded the study.John Sims, M.D., of Eli Lilly and colleagues conducte...
Source: Psychiatr News - July 18, 2023 Category: Psychiatry Tags: Alzheimer ' s disease amyloid plaques antibody disease progression donanemab Eli Lilly JAMA Source Type: research
