Protocol: dexmedetomidine on myocardial injury after noncardiac surgery —a multicenter, double-blind, controlled trial
DiscussionThe results of the current study will illustrate the effect of dexmedetomidine on myocardial injury for elderly patients undergoing major noncardiac surgery.Trial registrationThe trial was registered with Chinese Clinical Trial Registry (CHICTR) on Aug 24, 2021 (ChiCTR2100049946,http://www.chictr.org.cn/showproj.aspx?proj=131804). (Source: Perioperative Medicine)
Source: Perioperative Medicine - November 11, 2023 Category: Surgery Source Type: research
Preoperative moderate to severe anemia is associated with increased postoperative major adverse cardiac and cerebral events and pulmonary complications: a propensity score-matched analysis in hip fracture surgery patients over 80 years old
ConclusionsModerate to severe preoperative anemia (< 11 g/dl) is associated with increased postoperative major adverse cardiac and cerebral events and pulmonary complications. Additionally, in-hospital mortality was not significant but was higher in the preoperative moderate to severe anemia cohort. Preoperative assessment and correction of hemogl obin level to above 11 g/dl might reduce MACCE, PPCs, and in-hospital mortality in hip fracture patients over 80 years old. (Source: Perioperative Medicine)
Source: Perioperative Medicine - November 10, 2023 Category: Surgery Source Type: research
The impact of preoperative malnutrition on postoperative delirium: a systematic review and meta-analysis
ConclusionsBased on the currently available evidence, our results suggested that preoperative malnutrition was independently associated with POD in adult surgical patients. (Source: Perioperative Medicine)
Source: Perioperative Medicine - October 26, 2023 Category: Surgery Source Type: research
Significant perioperative parameters affecting postoperative complications within 30 days following craniotomy for primary malignant brain tumors
ConclusionsFour parameters were demonstrated to significantly influence the risk of PC1M in patients undergoing primary malignant brain tumor removal. Measuring and verifying these markers, especially kinetic estimated glomerular filtration rate, would help early recognition of PC1M risk in clinical care. (Source: Perioperative Medicine)
Source: Perioperative Medicine - October 23, 2023 Category: Surgery Source Type: research
Unplanned admissions after day-case surgery in an Italian third-level pediatric hospital: a retrospective study
ConclusionsGood quality of patient selection, the safety of the structure, family education, and an efficient organizational model combined with an educational program for anesthesiologists can improve the safety of anesthesia for day-case surgery. (Source: Perioperative Medicine)
Source: Perioperative Medicine - September 26, 2023 Category: Surgery Source Type: research
Restrictive versus conventional ward fluid therapy in non-cardiac surgery patients and the effect on postoperative complications: a meta-analysis
ConclusionThis meta-analysis suggests restrictive fluid therapy on the ward may be associated with an effect on postoperative complication rate. However, the quality of evidence was moderate to low, the sample size was small, and the data came from both RCTs and non-randomized studies. (Source: Perioperative Medicine)
Source: Perioperative Medicine - September 21, 2023 Category: Surgery Source Type: research
Effect of chamomile intake on blood coagulation tests in healthy volunteers: a randomized, placebo-controlled, crossover trial
ConclusionsChamomile intake by tea or capsule does not prolong PT. These findings challenge the notion to avoid perioperative chamomile intake in patients not taking warfarin.Trial registrationClinicalTrials.gov, NCT05006378; Principal Investigator: Jonathon Schwartz, M.D.; Registered August 16, 2021. (Source: Perioperative Medicine)
Source: Perioperative Medicine - September 20, 2023 Category: Surgery Source Type: research
Perioperative mortality of emergency and elective surgical patients in a low-income country: a single institution experience
ConclusionMore than two thirds of patients died within 7 postoperative days. More emergency patients died than elective counterparts, and emergency cases had a higher rate of dying within 7 days of surgery. Poor ASA performance score was associated with earlier postoperative death. Further prospective multi-institutional studies are warranted to elucidate the factors that contribute to higher postoperative mortality in low-income country patients. (Source: Perioperative Medicine)
Source: Perioperative Medicine - September 16, 2023 Category: Surgery Source Type: research
The effect of COVID-19 pandemic on perioperative factors: data from the Swedish Perioperative Register
ConclusionsThe COVID-19 pandemic has had an impact on perioperative care in Sweden. During the first wave of the pandemic, the number of surgical interventions decreased, but the number of acute surgeries remained stable compared with pre-pandemic numbers. Perioperative organizations have had and will continue to have challenges handling the increased number of patients needing perioperative care. (Source: Perioperative Medicine)
Source: Perioperative Medicine - September 16, 2023 Category: Surgery Source Type: research
Reporting quality of randomized controlled trials in prehabilitation: a scoping review
ConclusionAltogether, existing prehabilitation trials report approximately half of the checklist items recommended by methodological and intervention reporting guidelines. Reporting practices may improve with the development of a reporting checklist specific to prehabilitation interventions. (Source: Perioperative Medicine)
Source: Perioperative Medicine - August 31, 2023 Category: Surgery Source Type: research
Prevalence of preoperative anxiety among hospitalized patients in a developing country: a study of associated factors
ConclusionPreoperative anxiety was prevalent among patients scheduled for surgical operations in Palestinian hospitals. Anesthesiologists and other providers of perioperative care should screen preoperative patients who are female, have chronic diseases, are scheduled to be operated on within 24 h, and having had experienced surgical complications for preoperative anxiety. More studies are still needed to investigate the effects of the implemented measures on the prevalence of preoperative anxiety. (Source: Perioperative Medicine)
Source: Perioperative Medicine - August 24, 2023 Category: Surgery Source Type: research
Comparison of two handgrip dynamometers in older adults before elective surgery
ConclusionCamry digital dynamometer is an inexpensive and valid device to measure handgrip strength in older adults previous to elective surgery, compared to the gold standard Jamar ® hydraulic handgrip dynamometer. (Source: Perioperative Medicine)
Source: Perioperative Medicine - August 23, 2023 Category: Surgery Source Type: research
Randomized controlled trial of liberal vs. standard fasting instructions in percutaneous cardiac procedures
ConclusionNo adverse events or case delays were observed in the ad libitum clears group. No significant benefit, however, was observed in patient satisfaction or any of the pre-specified secondary endpoints in patients randomized to ad libitum clear liquids up to 2 h prior to their procedure.Trial registrationNCT04079543. (Source: Perioperative Medicine)
Source: Perioperative Medicine - August 8, 2023 Category: Surgery Source Type: research
Outpatient compared to inpatient thyroidectomy on 30-day postoperative outcomes: a national propensity matched analysis
ConclusionThyroidectomy procedures performed in the outpatient setting had less rates of adverse events, including serious postoperative complications (e.g., surgical site infection, pneumonia, progressive renal insufficiency). In addition, patients who had thyroidectomy in the outpatient setting had less 30-day readmissions and mortality. Surgeons should recognize the benefits of outpatient thyroidectomy when selecting disposition of patients undergoing neck surgery. (Source: Perioperative Medicine)
Source: Perioperative Medicine - August 8, 2023 Category: Surgery Source Type: research
A multidisciplinary opioid-reduction pathway for robotic prostatectomy: outcomes at year one
ConclusionsThese findings underscore the effectiveness of a multidisciplinary approach to reduce opioids. Furthermore, it demonstrates improved patient outcomes as measured by both shorter PACU and almost 50% reduction in perioperative opioid use whilst maintaining similar analgesia as indicated by patient-reported pain scores. (Source: Perioperative Medicine)
Source: Perioperative Medicine - August 1, 2023 Category: Surgery Source Type: research
