Effect of intravenous lidocaine on the ED50 of propofol induction dose in elderly patients undergoing painless gastroscopy: a prospective, randomized, double-blinded, controlled study
ConclusionsThe administration of intravenous lidocaine to elderly patients undergoing painless gastroscopy resulted in a significant 40% reduction in the ED50 of propofol induction dose, which may be related to the decreased incidence of hypotension and injection pain, as well as the improved post-gastroscopy orientation recovery.Trial registrationChiCTR, ChiCTR2200065530. Registered on 08 November 2022. (Source: Perioperative Medicine)
Source: Perioperative Medicine - March 5, 2024 Category: Surgery Source Type: research
Pulmonary function testing in preoperative high-risk patients
ConclusionsOur screening program detected a relevant number of patients with previously unknown obstructive ventilatory disorders and impaired pulmonary gas exchange. This newly discovered sickness is associated with low metabolic equivalents and may influence perioperative outcomes. Whether optimized management of patients with previously unknown impaired lung function leads to a better outcome should be evaluated in multicenter studies.Trial registrationGerman Registry of Clinical Studies (DRKS00029337), registered on: June 22nd, 2022. (Source: Perioperative Medicine)
Source: Perioperative Medicine - March 5, 2024 Category: Surgery Source Type: research
AcumenTM hypotension prediction index guidance for prevention and treatment of hypotension in noncardiac surgery: a prospective, single-arm, multicenter trial
ConclusionsThe use of prediction software for blood pressure management was associated with a clinically meaningful reduction in the duration of intraoperative hypotension. Further studies must investigate whether predictive algorithms to prevent hypotension can reduce adverse outcomes.Trial registrationClinical trial number: NCT03805217. Registry URL:https://clinicaltrials.gov/ct2/show/NCT03805217. Principal investigator: Xiaodong Bao, MD, PhD. Date of registration: January 15, 2019. (Source: Perioperative Medicine)
Source: Perioperative Medicine - March 4, 2024 Category: Surgery Source Type: research
Preoperative endothelial dysfunction for the prediction of acute kidney injury after cardiac surgery using cardiopulmonary bypass: a pilot study based on a second analysis of the MONS study
ConclusionsThe preoperative peak amplitude of endothelium-dependent vasodilation is independently associated with the postoperative occurrence of AKI.Trial registrationClinical-Trials.gov, NCT03631797. Registered 15 August 2018,https://clinicaltrials.gov/ct2/show/NCT03631797 (Source: Perioperative Medicine)
Source: Perioperative Medicine - February 29, 2024 Category: Surgery Source Type: research
Sevoflurane preconditioning in living liver donation is associated with better initial graft function after pediatric transplantation: a retrospective study
ConclusionSignificantly fewer children who received a graft from a donor in whom only sevoflurane was used to maintain anesthesia developed IPGF. Although additional research is needed, this preconditioning strategy may provide an option to prevent IPGF after living liver donation. (Source: Perioperative Medicine)
Source: Perioperative Medicine - February 28, 2024 Category: Surgery Source Type: research
A new risk calculation model for complications of hepatectomy in adults over 75
ConclusionRASHA can be used to effectively predict the postoperative complications of hepatectomy through perioperative variables in adults older than 75 years.Trial registrationThe Research Registry: researchregistry8531.https://www.researchregistry.com/browse-the-registry#home/registrationdetails/63901824ae49230021a5a0cf/. (Source: Perioperative Medicine)
Source: Perioperative Medicine - February 26, 2024 Category: Surgery Source Type: research
Comparison of two 3D scanning software to identify facial features: a prospective instrument to predict difficult airway
ConclusionThree-dimensional facial scanning with Scandy Pro is an accurate tool that can be a cost-effective alternative to high-fidelity scans produced by the Artec Space Spider. (Source: Perioperative Medicine)
Source: Perioperative Medicine - February 22, 2024 Category: Surgery Source Type: research
Impact of preoperative factors and waiting time on post-appendectomy complications: a retrospective study
ConclusionsThe surgical outcome may be affected by preoperative factors and time to surgery. It is suggested that high-risk patients receive appendectomy within 12 hours to avoid increased postoperative complications. (Source: Perioperative Medicine)
Source: Perioperative Medicine - February 21, 2024 Category: Surgery Source Type: research
Clinical effect of different concentrations of ropivacaine in the labor analgesia of dural puncture epidural technique for obese puerperae
Conclusion0.1% ropivacaine combined with 0.5 μg/ml sufentanil through DPE technique has good analgesic efficacy and few adverse effects in obese puerperae. (Source: Perioperative Medicine)
Source: Perioperative Medicine - February 15, 2024 Category: Surgery Source Type: research
Multidisciplinary prehabilitation to improve frailty and functional capacity in high-risk elective surgical patients: a retrospective pilot study
ConclusionsThis outpatient-based, one-stop multidisciplinary prehabilitation programme was feasible, safe, and improved several measures of patient ’s physiological reserve and functional capacity.Clinical trial registrationNCT05668221. (Source: Perioperative Medicine)
Source: Perioperative Medicine - January 23, 2024 Category: Surgery Source Type: research
Desmopressin to reduce periprocedural bleeding and transfusion: a systematic review and meta-analysis
In conclusion, desmopressin likely re duces periprocedural blood loss and the number of units of blood transfused in small trials with methodologic limitations. However, the risk of hypotension needs to be mitigated. Large trials should evaluate desmopressin alongside tranexamic acid and enroll patients with advanced kidney disease. (Source: Perioperative Medicine)
Source: Perioperative Medicine - January 23, 2024 Category: Surgery Source Type: research
Days at home alive after major surgery in patients with and without diabetes: an observational cohort study
ConclusionsThe results of this large cohort study are likely broadly generalizable. To optimize patient and societal outcomes, specific perioperative care pathways for patients with diabetes should be evaluated. (Source: Perioperative Medicine)
Source: Perioperative Medicine - January 22, 2024 Category: Surgery Source Type: research
Postoperative and postdischarge nausea and vomiting following ambulatory eye, head, and neck surgeries: a retrospective cohort study comparing incidence and associated factors
ConclusionsPatients experiencing N/V in the PACU are observed to develop PDNV disproportionately by a factor of 2.79. The patients have distinct predictors, indicating important opportunities for care improvements beyond current guidelines. (Source: Perioperative Medicine)
Source: Perioperative Medicine - January 20, 2024 Category: Surgery Source Type: research
Correction: A comparative study on the effect of dopamine vs phenylephrine in improving the cutaneous analgesic effect of mexiletine in rats
(Source: Perioperative Medicine)
Source: Perioperative Medicine - January 11, 2024 Category: Surgery Source Type: research
Examining workload variations among different surgical team roles, specialties, and techniques: a multicenter cross-sectional descriptive study
ConclusionsThe results of the study showed that the workload for some members of the surgical team is disproportionately high and is influenced by factors such as specialty, technique, role, and surgical duration. By knowing the distribution of workload among the members of the surgical team, efforts can be made to optimize the team members ’ workload. (Source: Perioperative Medicine)
Source: Perioperative Medicine - January 2, 2024 Category: Surgery Source Type: research
