Naloxegol (Movantik ®) Provides Rapid and Sustained Improvement of Opioid-Induced Constipation Symptoms Irrespective of Opioid Dose
Naloxegol (Movantik), an oral peripherally acting mu-opioid receptor antagonist has demonstrated rapid relief of opioid-induced constipation (OIC) in patients with chronic non-cancer pain in two phase 3 trials (KODIAC 4/5; NCT01309841/NCT01323790). This analysis aims to characterize the OIC symptom burden and evaluate the efficacy of naloxegol in treating symptoms of OIC based on daily opioid dosages. This is the first naloxegol analysis based on a lower opioid dose cutoff of 100 MEU/day. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Charles McLeskey, Jeffrey Gudin, Jeremy Adler, Carol Rockett, Mansi Jamindar, Richard Rauck, Lynn Webster, Theresa Mallick-Searle Source Type: research
Virtual Reality & Acute Pain: A Literature Review
Safe and effective pain management is a challenge among hospitalized patients. Pharmacological interventions are often the first choice but are associated with side effects and can contribute to the opioid epidemic. Nonpharmacological interventions, such as virtual reality (VR), may be an effective adjuvant in pain reduction. This literature review addressed the following question: Does VR compared to standard treatment reduce pain in hospitalized adult patients? (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Anna Larkin Source Type: research
Naloxegol (Movantik ®) Provides Rapid Response and Sustained Improvement of Opioid-Induced Constipation Symptoms in Older Adults
Naloxegol (Movantik ®), an oral peripherally acting mu-opioid receptor antagonist (PAMORA) has demonstrated rapid and predictable relief of OIC in patients treated with opioids for chronic non-cancer pain in two phase 3 trials (KODIAC 4/5; NCT01309841/NCT01323790). In subjects ≥65 yrs, naloxegol (25mg, 12.5mg) demon strated significantly better response rates, clinically relevant early symptom relief, and predictable efficacy compared with PBO. Improvements in SBMs, CSBMs, straining, and stool consistency were rapid and sustained across 12 weeks. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Charles McLeskey, Darren Brenner, Carol Rockett, Mansi Jamindar, Enoch Bortey, Martin Hale, Theresa Mallick-Searle Source Type: research
Interprofessional Pain Curriculum for an Academic Health Science Center
The aim of this project is to develop a comprehensive pain curriculum to educate a diverse group of students across health care disciplines who care for those in pain. The outcome goals for participants of this educational program are to have increased knowledge and skills associated with the management of pain. This poster will describe the process of team development, development of the grant proposal, conducting a gap analysis, designing and developing the content of the program, and finally the integration of technology as we prepare for program delivery. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Kelly Allred, Carey Rothschild, James Whitworth, Jeffrey E. Cassisi Source Type: research
Treatment of DPN with 8% topical capsaicin without the use of a topical anesthetic
A qualitative study was done to look at the use of 8% topical capsaicin without the use of a topical anesthetic prior to treatment of DPN. In the PI it is indicated to anesthetize the affected area with topical lidocaine prior to the treatment for painful diabetic peripheral neuropathy of the feet. Many patients with diabetic peripheral neuropathy have significant numbness in their feet and limited feeling and there may not be a need for a topical anesthetic prior to application of the topical system. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Stephanie Simon Source Type: research
Enhanced Recovery After Surgery in a Veteran Population
ERAS protocols have improved our pain management (via patient satisfaction scores) while decreasing post op opioids used and decreasing complications and length of stay. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Vada R Taylor Source Type: research
Prospective Study of Masimo NSS-2 BRIDGE; as a Non-Pharmacological Treatment for Acute Opioid Withdrawal Symptoms
Opioids are commonly employed for treatment of acute and chronic pain. However, continued opioid use can lead to opioid use disorder. Opioid withdrawal symptoms can be severe, and avoidance of the discomfort is a key barrier to voluntary discontinuation. The NSS-2 BRIDGE ™ (Masimo Corporation, Irvine, CA) is a percutaneous nerve field stimulator that can decrease symptoms of acute opiate withdrawal. The device fits behind the ear and stimulates branches of Cranial Nerves V, VII, IX, X, and periauricular occipital nerves, which synapse with nuclei involved in proce ssing perception of pain and pleasure, as well as in addi...
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Carla Matta, Alexis Wieseler Source Type: research
Enhancing the Use of Opioid Sparing Protocol in the PACU
Opioids serve as the cornerstone for severe acute post-operative pain management in the PACU. Opioids have been used for their quick onset and efficacy without analgesic ceiling yet have significant side effects. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Analissa Chavez, Michael Tagadaya Source Type: research
Nurse-led Tele-Collaborative Pain Care for Rural Patients with Substance Use Disorder
Rates of chronic non-cancer pain in patients with substance use disorders (SUD) are higher than in patients without SUD. Yet access to evidence-based pain treatment for patients with SUD is limited, particularly in rural areas where care access is often poor. The purpose of this study was to examine feasibility and preliminary efficacy of a nurse-led collaborative pain intervention for patients with comorbid chronic pain and SUD, delivered exclusively via telehealth. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Patricia E. Maloy Source Type: research
Peripheral Nerve Stimulation for Knee Pain
Peripheral nerve stimulation (PNS) is a drug free pain management procedure that uses electrical impulses to target specific nerve and block pain signals. PNS helps decrease perception of pain, providing real answers to patients dealing with chronic knee pain. The case study discussed in this presentation is of use of PNS targeting the superior lateral genicular nerve and the saphenous nerve for a patient with severe knee pain from osteoarthritis. The patient discussed is a 49-year-old female with a history of chronic pain related to osteoarthritis of the left knee. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Khairunnisa Khan Source Type: research
Genetic Testing for Opioid Risk and Drug Metabolism: A Pain Clinic's Retrospective Cohort Study
Pharmacogenetics hold promise as an important clinical tool to individualize chronic pain treatment. Prescribing based on drug metabolism and other unique genetic characteristics can potentially decrease inherent risks of chronic opioid therapy. This IRB-approved retrospective study addressed the primary research question: Is there a significant association between genetic test results evaluating drug metabolism and clinical decision-making six months after the initial genetic test results? (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Danielle Schalk, Ellen Romesburg, Jamie Lewis, Marian Wilson Source Type: research
Fibromyalgia or Chronic Fatigue Educational Preferences: In-person vs Virtual
This study assessed if patients preferred in-person or virtual educational sessions for their treatment program during the COVID pandemic. We hypothesized a relatively even split as to the preference of in-person or virtual sessions. The FCFC, operational since 1999, consists of in-depth educational sessions, led by RN staff. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Connie Luedtke, Mary Volcheck, Shirley Johnson Source Type: research
Educational Innovations Leveraging Technology for Nurse Practitioner Students to Learn Pain Management
Innovative teaching modalities in curricular content and delivery of pain education for NP students are important given that at least 20% of adults suffer from chronic pain in the United States. In addition, at least 2 in 3 NPs perceive having lack of confidence and competence in managing patients with pain. Transforming pain education for NP students is necessary especially with advancing technology in this digital era. Academic programs can greatly assist in preparing NPs into pain practice to improve pain care among our patients. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Jennifer Kawi Source Type: research
Improving Pain Management through Creative Partnerships
Through the development of diverse partnerships across Stead Family Children's Hospital, we have improved access to a wide variety of evidence-based strategies to decrease pain and empowered patients and families with knowledge of the resources and how to utilize them. We will describe the partnerships we have formed and the outcomes we have measured in selected areas. Examples have included partnerships with our pharmacies to allow patients to purchase numbing cream as well as TENs units. Through a grant, we partnered with other team members to provide over 100 Buzzies to patients who will have regular, ongoing needle pro...
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Deb Bruene, Molly Bauer Source Type: research
Social Connectedness and Pain
Research suggests that social interactions and connections consistently play a pivotal role in pain perception and coping (Karayannis, et al. 2019). Individuals with higher social connectedness tend to feel close with others, identify with them, and readily engage in social activities and groups (Baumgartner, et al., 2023). Moreover, high-quality social connections are essential to our mental health, physical health, overall sense of well-being, and longevity (Halcomb, et. al., 2022). On the other hand, socially disconnected individuals tend to perceive themselves as outsiders, feel misunderstood by others, and experience ...
Source: Pain Management Nursing - April 1, 2023 Category: Nursing Authors: Elaine L. Miller Tags: Editorial Source Type: research
