Predicting Objective Response of Pembrolizumab in Platinum-Refractory Urothelial Carcinoma Based on NLR Fluctuation and Liver Metastases
CONCLUSIONS: At the six weeks of the pembrolizumab treatment, our risk model predicts the objective response rate precisely. Notably, those classified as 'poor risk'-marked by liver metastasis and a heightened NLR-should be considered for alternative therapy with a different mode of action, highlighting a critical decision point in treatment optimization.PMID:37839399 | DOI:10.1159/000534554 (Source: Oncology)
Source: Oncology - October 15, 2023 Category: Cancer & Oncology Authors: Kyosuke Nishio Takuya Higashio Kazumasa Komura Wataru Fukuokaya Takahiro Adachi Yosuke Hirasawa Takeshi Hashimoto Atsuhiko Yoshizawa Shuya Tsuchida Takuya Matsuda Takuya Tsujino Kazuki Nishimura Satoshi Tokushige Keita Nakamori Taizo Uchimoto Shutaro Yama Source Type: research

Outcomes and Feasibility of an Occupational Care Programme (TERRA) to Support Work Ability of Rare and Advanced Cancer Patients: A Report of 7 Cases
CONCLUSION: A multidisciplinary approach may further improve outcomes of occupational interventions supporting rare and advanced cancer patients. An effectiveness study to evaluate the outcomes and feasibility of the programme is deemed necessary.PMID:37827131 | DOI:10.1159/000534451 (Source: Oncology)
Source: Oncology - October 12, 2023 Category: Cancer & Oncology Authors: Floortje L Hosman Sascha C A Rozemeijer Amber D Zegers Annemarie Becker-Commissaris Heinz-Josef Kl ümpen Maurice J D L van der Vorst Linda Brom Saskia F A Duijts Source Type: research

Comprehensive analysis of the relationship between cuproptosis-related gene GCSH and prognosis, tumor microenvironment infiltration, and therapy response in endometrial cancer
CONCLUSION: This study revealed the role of GCSH in TME, response to therapy, and clinical prognosis in EC, which provided novel insights for the therapeutic application in EC.PMID:37827132 | DOI:10.1159/000534018 (Source: Oncology)
Source: Oncology - October 12, 2023 Category: Cancer & Oncology Authors: Mengya Zhao Haihang Nie Peishan Qiu Yali Yu Haizhou Wang Fan Wang Jun Fang Qiu Zhao Source Type: research

Outcomes and Feasibility of an Occupational Care Programme (TERRA) to Support Work Ability of Rare and Advanced Cancer Patients: A Report of 7 Cases
CONCLUSION: A multidisciplinary approach may further improve outcomes of occupational interventions supporting rare and advanced cancer patients. An effectiveness study to evaluate the outcomes and feasibility of the programme is deemed necessary.PMID:37827131 | DOI:10.1159/000534451 (Source: Oncology)
Source: Oncology - October 12, 2023 Category: Cancer & Oncology Authors: Floortje L Hosman Sascha C A Rozemeijer Amber D Zegers Annemarie Becker-Commissaris Heinz-Josef Kl ümpen Maurice J D L van der Vorst Linda Brom Saskia F A Duijts Source Type: research

Comprehensive analysis of the relationship between cuproptosis-related gene GCSH and prognosis, tumor microenvironment infiltration, and therapy response in endometrial cancer
CONCLUSION: This study revealed the role of GCSH in TME, response to therapy, and clinical prognosis in EC, which provided novel insights for the therapeutic application in EC.PMID:37827132 | DOI:10.1159/000534018 (Source: Oncology)
Source: Oncology - October 12, 2023 Category: Cancer & Oncology Authors: Mengya Zhao Haihang Nie Peishan Qiu Yali Yu Haizhou Wang Fan Wang Jun Fang Qiu Zhao Source Type: research

Outcomes and Feasibility of an Occupational Care Programme (TERRA) to Support Work Ability of Rare and Advanced Cancer Patients: A Report of 7 Cases
CONCLUSION: A multidisciplinary approach may further improve outcomes of occupational interventions supporting rare and advanced cancer patients. An effectiveness study to evaluate the outcomes and feasibility of the programme is deemed necessary.PMID:37827131 | DOI:10.1159/000534451 (Source: Oncology)
Source: Oncology - October 12, 2023 Category: Cancer & Oncology Authors: Floortje L Hosman Sascha C A Rozemeijer Amber D Zegers Annemarie Becker-Commissaris Heinz-Josef Kl ümpen Maurice J D L van der Vorst Linda Brom Saskia F A Duijts Source Type: research

Comprehensive analysis of the relationship between cuproptosis-related gene GCSH and prognosis, tumor microenvironment infiltration, and therapy response in endometrial cancer
CONCLUSION: This study revealed the role of GCSH in TME, response to therapy, and clinical prognosis in EC, which provided novel insights for the therapeutic application in EC.PMID:37827132 | DOI:10.1159/000534018 (Source: Oncology)
Source: Oncology - October 12, 2023 Category: Cancer & Oncology Authors: Mengya Zhao Haihang Nie Peishan Qiu Yali Yu Haizhou Wang Fan Wang Jun Fang Qiu Zhao Source Type: research

Simple scoring system for esophagogastric varices prediction in hepatocellular carcinoma patients without liver stiffness evaluation
CONCLUSION: The findings indicate that REGS score can provide useful predictive information for development of significant EGV without the need for special equipment such as a FibroScan®.PMID:37820607 | DOI:10.1159/000533672 (Source: Oncology)
Source: Oncology - October 11, 2023 Category: Cancer & Oncology Authors: Atsushi Hiraoka Fujimasa Tada Hideko Ohama Mai Fukumoto Kana Matsuoka Takuya Matsuda Kosuke Nakatani Emi Yanagihara Hironobu Saneto Hirofumi Izumoto Taisei Murakami Kei Onishi Shogo Kitahata Kozue Kanemitsu-Okada Tomoe Kawamura Taira Kuroda Hideki Miyata Source Type: research

Simple scoring system for esophagogastric varices prediction in hepatocellular carcinoma patients without liver stiffness evaluation
CONCLUSION: The findings indicate that REGS score can provide useful predictive information for development of significant EGV without the need for special equipment such as a FibroScan®.PMID:37820607 | DOI:10.1159/000533672 (Source: Oncology)
Source: Oncology - October 11, 2023 Category: Cancer & Oncology Authors: Atsushi Hiraoka Fujimasa Tada Hideko Ohama Mai Fukumoto Kana Matsuoka Takuya Matsuda Kosuke Nakatani Emi Yanagihara Hironobu Saneto Hirofumi Izumoto Taisei Murakami Kei Onishi Shogo Kitahata Kozue Kanemitsu-Okada Tomoe Kawamura Taira Kuroda Hideki Miyata Source Type: research

Effects of lobectomy versus sub-lobar resection on the survival in adults with stage IA left upper lobe non-small cell lung cancer: a retrospective cohort study based on the SEER database
CONCLUSION: The SLR was inferior to LR on the survival of NSCLC patients with stage IA.PMID:37812916 | DOI:10.1159/000534195 (Source: Oncology)
Source: Oncology - October 9, 2023 Category: Cancer & Oncology Authors: Huanshun Wen Chaoyang Liang Source Type: research

Kinesin family member B18 is related to gastric mucin phenotype and contributes to gastric cancer progression by regulating epithelial-mesenchymal transition
CONCLUSION: These findings not only suggest that KIF18B may be a useful prognostic marker, but also provide insight into the pathogenesis of the GC phenotype.PMID:37812924 | DOI:10.1159/000533791 (Source: Oncology)
Source: Oncology - October 9, 2023 Category: Cancer & Oncology Authors: Akira Ishikawa Ryo Yasumatsu Takafumi Fukui Aya Kido Narutaka Katsuya Kazuhiro Sentani Kazuya Kuraoka Naohide Oue Takahisa Suzuki Shiro Oka Takahiro Kotachi Kazuaki Tanabe Hideki Ohdan Hassan Ashktorab Duane Smoot Wataru Yasui Source Type: research

Effects of lobectomy versus sub-lobar resection on the survival in adults with stage IA left upper lobe non-small cell lung cancer: a retrospective cohort study based on the SEER database
CONCLUSION: The SLR was inferior to LR on the survival of NSCLC patients with stage IA.PMID:37812916 | DOI:10.1159/000534195 (Source: Oncology)
Source: Oncology - October 9, 2023 Category: Cancer & Oncology Authors: Huanshun Wen Chaoyang Liang Source Type: research

Kinesin family member B18 is related to gastric mucin phenotype and contributes to gastric cancer progression by regulating epithelial-mesenchymal transition
CONCLUSION: These findings not only suggest that KIF18B may be a useful prognostic marker, but also provide insight into the pathogenesis of the GC phenotype.PMID:37812924 | DOI:10.1159/000533791 (Source: Oncology)
Source: Oncology - October 9, 2023 Category: Cancer & Oncology Authors: Akira Ishikawa Ryo Yasumatsu Takafumi Fukui Aya Kido Narutaka Katsuya Kazuhiro Sentani Kazuya Kuraoka Naohide Oue Takahisa Suzuki Shiro Oka Takahiro Kotachi Kazuaki Tanabe Hideki Ohdan Hassan Ashktorab Duane Smoot Wataru Yasui Source Type: research

Effects of lobectomy versus sub-lobar resection on the survival in adults with stage IA left upper lobe non-small cell lung cancer: a retrospective cohort study based on the SEER database
CONCLUSION: The SLR was inferior to LR on the survival of NSCLC patients with stage IA.PMID:37812916 | DOI:10.1159/000534195 (Source: Oncology)
Source: Oncology - October 9, 2023 Category: Cancer & Oncology Authors: Huanshun Wen Chaoyang Liang Source Type: research

Kinesin family member B18 is related to gastric mucin phenotype and contributes to gastric cancer progression by regulating epithelial-mesenchymal transition
CONCLUSION: These findings not only suggest that KIF18B may be a useful prognostic marker, but also provide insight into the pathogenesis of the GC phenotype.PMID:37812924 | DOI:10.1159/000533791 (Source: Oncology)
Source: Oncology - October 9, 2023 Category: Cancer & Oncology Authors: Akira Ishikawa Ryo Yasumatsu Takafumi Fukui Aya Kido Narutaka Katsuya Kazuhiro Sentani Kazuya Kuraoka Naohide Oue Takahisa Suzuki Shiro Oka Takahiro Kotachi Kazuaki Tanabe Hideki Ohdan Hassan Ashktorab Duane Smoot Wataru Yasui Source Type: research