Is total neoadjuvant treatment beneficial for locally advanced rectal cancer? a meta-analysis of randomized controlled trials
CONCLUSIONS: In the treatment of locally advanced rectal cancer, TNT offers greater survival benefits compared to neoadjuvant CRT and does not significantly increase the incidence of adverse events. However, further data and studies with long-term outcomes are still required.PMID:37926087 | DOI:10.1159/000534815 (Source: Oncology)
Source: Oncology - November 5, 2023 Category: Cancer & Oncology Authors: Hai-Qiong Wu Jun Li Ji-Dong Miao Jia-Wei Li Source Type: research

Clinicopathological characteristics and survival outcomes in patients with advanced esophageal squamous cell carcinoma who were intraoperatively diagnosed non-curative
CONCLUSIONS: T4b tumor located in aortobronchial constriction or trachea/bronchus makes it difficult to diagnose whether it is resectable or unresectable. Moreover, surgical procedures and perioperative treatment were deeply associated with the clinical outcomes.PMID:37926097 | DOI:10.1159/000533772 (Source: Oncology)
Source: Oncology - November 5, 2023 Category: Cancer & Oncology Authors: Takahito Sugase Takashi Kanemura Tomohira Takeoka Keijiro Sugimura Masaaki Yamamoto Naoki Shinno Hisashi Hara Takeshi Omori Yosuke Mukai Manabu Mikamori Shinichiro Hasegawa Naotsugu Haraguchi Hirofumi Akita Junichi Nishimura Hiroshi Wada Chu Matsuda Masay Source Type: research

Is total neoadjuvant treatment beneficial for locally advanced rectal cancer? a meta-analysis of randomized controlled trials
CONCLUSIONS: In the treatment of locally advanced rectal cancer, TNT offers greater survival benefits compared to neoadjuvant CRT and does not significantly increase the incidence of adverse events. However, further data and studies with long-term outcomes are still required.PMID:37926087 | DOI:10.1159/000534815 (Source: Oncology)
Source: Oncology - November 5, 2023 Category: Cancer & Oncology Authors: Hai-Qiong Wu Jun Li Ji-Dong Miao Jia-Wei Li Source Type: research

Clinicopathological characteristics and survival outcomes in patients with advanced esophageal squamous cell carcinoma who were intraoperatively diagnosed non-curative
CONCLUSIONS: T4b tumor located in aortobronchial constriction or trachea/bronchus makes it difficult to diagnose whether it is resectable or unresectable. Moreover, surgical procedures and perioperative treatment were deeply associated with the clinical outcomes.PMID:37926097 | DOI:10.1159/000533772 (Source: Oncology)
Source: Oncology - November 5, 2023 Category: Cancer & Oncology Authors: Takahito Sugase Takashi Kanemura Tomohira Takeoka Keijiro Sugimura Masaaki Yamamoto Naoki Shinno Hisashi Hara Takeshi Omori Yosuke Mukai Manabu Mikamori Shinichiro Hasegawa Naotsugu Haraguchi Hirofumi Akita Junichi Nishimura Hiroshi Wada Chu Matsuda Masay Source Type: research

Association between artificial sweeteners-aspartame consumption and colorectal cancer risk: evidence-based strategies
In this study, clinical trials were generalized, summarized, and meta-analyzed to evaluate correlations between artificial sweeteners (ASs) and colorectal cancer (CRC). PubMed, Web of Science, EMBASE (Ovid platform), MEDLINE, and the Cochrane Library databases were searched from inception until July 24, 2023. The association between AS exposure and CRC incidence was assessed using odds ratios (ORs) and 95% confidence intervals (CIs). STATA software (version 12.0) was used to perform the meta-analysis. Ten studies (three case-control studies and seven cohort studies) involving 711,537 participants were identified. Results s...
Source: Oncology - November 2, 2023 Category: Cancer & Oncology Authors: Chenglou Zhu Dandan Ji Jichun Ma Mingxu Da Source Type: research

Association between artificial sweeteners-aspartame consumption and colorectal cancer risk: evidence-based strategies
In this study, clinical trials were generalized, summarized, and meta-analyzed to evaluate correlations between artificial sweeteners (ASs) and colorectal cancer (CRC). PubMed, Web of Science, EMBASE (Ovid platform), MEDLINE, and the Cochrane Library databases were searched from inception until July 24, 2023. The association between AS exposure and CRC incidence was assessed using odds ratios (ORs) and 95% confidence intervals (CIs). STATA software (version 12.0) was used to perform the meta-analysis. Ten studies (three case-control studies and seven cohort studies) involving 711,537 participants were identified. Results s...
Source: Oncology - November 2, 2023 Category: Cancer & Oncology Authors: Chenglou Zhu Dandan Ji Jichun Ma Mingxu Da Source Type: research

Association between artificial sweeteners-aspartame consumption and colorectal cancer risk: evidence-based strategies
In this study, clinical trials were generalized, summarized, and meta-analyzed to evaluate correlations between artificial sweeteners (ASs) and colorectal cancer (CRC). PubMed, Web of Science, EMBASE (Ovid platform), MEDLINE, and the Cochrane Library databases were searched from inception until July 24, 2023. The association between AS exposure and CRC incidence was assessed using odds ratios (ORs) and 95% confidence intervals (CIs). STATA software (version 12.0) was used to perform the meta-analysis. Ten studies (three case-control studies and seven cohort studies) involving 711,537 participants were identified. Results s...
Source: Oncology - November 2, 2023 Category: Cancer & Oncology Authors: Chenglou Zhu Dandan Ji Jichun Ma Mingxu Da Source Type: research

Effects of Laughter Therapy on Improving Negative Emotions Associated with Cancer: A Systematic Review and Meta-Analysis
CONCLUSIONS: Laughter therapy is a convenient, multi-modality, flexible-duration therapy to improve negative emotions in cancer patients, regardless of their gender, age, and type of cancer.PMID:37906984 | DOI:10.1159/000533690 (Source: Oncology)
Source: Oncology - October 31, 2023 Category: Cancer & Oncology Authors: Hongyu Shi Yuejin Wu Lu Wang Xiuling Zhou Feng Li Source Type: research

Effects of Laughter Therapy on Improving Negative Emotions Associated with Cancer: A Systematic Review and Meta-Analysis
CONCLUSIONS: Laughter therapy is a convenient, multi-modality, flexible-duration therapy to improve negative emotions in cancer patients, regardless of their gender, age, and type of cancer.PMID:37906984 | DOI:10.1159/000533690 (Source: Oncology)
Source: Oncology - October 31, 2023 Category: Cancer & Oncology Authors: Hongyu Shi Yuejin Wu Lu Wang Xiuling Zhou Feng Li Source Type: research

Erratum
Oncology. 2023 Oct 12:1. doi: 10.1159/000534436. Online ahead of print.NO ABSTRACTPMID:37903463 | DOI:10.1159/000534436 (Source: Oncology)
Source: Oncology - October 30, 2023 Category: Cancer & Oncology Source Type: research

Chemoradiotherapy combined with immunotherapy in stage III non-small cell lung cancer: a systematic review and meta-analysis of efficacy and safety outcomes
Conclusions Prolonging the duration of immunotherapy consolidation increases survival benefits in patients with stage III NSCLC without causing higher side effects. Older patients, due to high incidence of pneumonia and low immunotherapy completion rate, have less survival benefit.PMID:37903484 | DOI:10.1159/000534376 (Source: Oncology)
Source: Oncology - October 30, 2023 Category: Cancer & Oncology Authors: Yang Li Guodong Deng Ning Liang Pingping Hu Yan Zhang Lili Qiao Yingying Zhang Jian Xie Hui Luo Fei Wang Fangjie Chen Fengjun Liu Deguo Xu Jiandong Zhang Source Type: research

Comparison of efficacy and safety between carboplatin-etoposide and cisplatin-etoposide combination therapy in patients with advanced neuroendocrine carcinoma, retrospective study
CONCLUSION: The efficacy of CE and PE in patients with NEC is comparable. However, the incidence of renal dysfunction was found to be significantly higher in the PE group than in the CE group.PMID:37903486 | DOI:10.1159/000534747 (Source: Oncology)
Source: Oncology - October 30, 2023 Category: Cancer & Oncology Authors: Hiroo Imai Ken Saijo Yoshifumi Kawamura Shuto Kodera Keigo Komine Tomoyuki Iwasaki Noriko Takenaga Yuki Kasahara Kota Ouchi Hidekazu Shirota Masanobu Takahashi Chikashi Ishioka Source Type: research

Erratum
Oncology. 2023 Oct 12:1. doi: 10.1159/000534436. Online ahead of print.NO ABSTRACTPMID:37903463 | DOI:10.1159/000534436 (Source: Oncology)
Source: Oncology - October 30, 2023 Category: Cancer & Oncology Source Type: research

Chemoradiotherapy combined with immunotherapy in stage III non-small cell lung cancer: a systematic review and meta-analysis of efficacy and safety outcomes
Conclusions Prolonging the duration of immunotherapy consolidation increases survival benefits in patients with stage III NSCLC without causing higher side effects. Older patients, due to high incidence of pneumonia and low immunotherapy completion rate, have less survival benefit.PMID:37903484 | DOI:10.1159/000534376 (Source: Oncology)
Source: Oncology - October 30, 2023 Category: Cancer & Oncology Authors: Yang Li Guodong Deng Ning Liang Pingping Hu Yan Zhang Lili Qiao Yingying Zhang Jian Xie Hui Luo Fei Wang Fangjie Chen Fengjun Liu Deguo Xu Jiandong Zhang Source Type: research

Comparison of efficacy and safety between carboplatin-etoposide and cisplatin-etoposide combination therapy in patients with advanced neuroendocrine carcinoma, retrospective study
CONCLUSION: The efficacy of CE and PE in patients with NEC is comparable. However, the incidence of renal dysfunction was found to be significantly higher in the PE group than in the CE group.PMID:37903486 | DOI:10.1159/000534747 (Source: Oncology)
Source: Oncology - October 30, 2023 Category: Cancer & Oncology Authors: Hiroo Imai Ken Saijo Yoshifumi Kawamura Shuto Kodera Keigo Komine Tomoyuki Iwasaki Noriko Takenaga Yuki Kasahara Kota Ouchi Hidekazu Shirota Masanobu Takahashi Chikashi Ishioka Source Type: research