CXCR4-targeted Theranostics in Hematooncology: Opportunities and Challenges
Nuklearmedizin. 2024 Jan 8. doi: 10.1055/a-2194-9965. Online ahead of print.ABSTRACTC-X-C motif chemokine receptor 4 (CXCR4) is overexpressed in a multitude of cancers, including neoplasms of hematopoietic origin. This feature can be leveraged by a theranostic approach, which provides a read-out of the actual CXCR4 expression in vivo, followed by CXCR4-targeted radioligand therapy (RLT) exerting anti-cancer as well as myeloablative efficacy. In a recent meeting of hematooncology and nuclear medicine specialists, statements on the current clinical practice and future perspectives of this innovative concept were proposed and...
Source: Nuklearmedizin - January 8, 2024 Category: Radiology Authors: Rudolf Werner Alexander Haug Christian Buske Simon Heidegger Anna L Illert Florian Bassermann Peter Herhaus Andreas Buck Johannes Duell Max S Topp Sabrina Kraus Hermann Einsele Constantin Lapa Markus Raderer Georg Lenz Stefan Habringer Bastian von Trescko Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Red Bull PET/CT
We report on a patient diagnosed with Hodgkin Lymphoma who was scheduled for [18F]FDG PET/CT as part of routine follow-up after treatment with two cycles of chemotherapy and mediastinal external beam radiation. Although the patient was advised to fast for at least four hours, an energy drink (Red Bull ) was ingested right after radiotracer administration, which led to increased uptake in the large skeletal muscles, thereby rendering this scan as non-diagnostic. After strictly following respective dietary recommendations, the repeated scan then provided excellent image quality and revealed response to treatment. In the pres...
Source: Nuklearmedizin - December 22, 2023 Category: Radiology Authors: Sebastian E Serfling Andreas Buck Steven P Rowe Takahiro Higuchi Rudolf Werner Source Type: research
Dementia with Lewy bodies: old and new knowledge-Part 2: treatment
DISCUSSION: The treatment of DLB with its various symptoms is difficult and often can only be adequately achieved for the patient in close cooperation with a specialist.PMID:38095659 | DOI:10.1007/s00115-023-01577-2 (Source: Nuklearmedizin)
Source: Nuklearmedizin - December 14, 2023 Category: Radiology Authors: Richard Dodel Daniela Berg Thomas Duning Elke Kalbe Philipp T Meyer Alfredo Ramirez Alexander Storch Dag Aarsland Frank Jessen Source Type: research
