Orbital inflammatory diseases
Radiologie (Heidelb). 2024 Feb 16. doi: 10.1007/s00117-024-01271-7. Online ahead of print.ABSTRACTCLINICAL/METHODICAL ISSUE: Inflammatory orbital processes on imaging are often misinterpreted as tumors.STANDARD RADIOLOGICAL METHODS: Imaging comprises computed tomography (CT) and magnetic resonance imaging (MRI).ACHIEVEMENTS: Clinical and laboratory data play a crucial role in diagnosing many inflammatory orbital diseases. Radiological imaging provides a supporting but relevant role.PRACTICAL RECOMMENDATIONS: Clinical examination, including specialized ophthalmological examinations, laboratory diagnostics, and MRI are impor...
Source: Nuklearmedizin - February 16, 2024 Category: Radiology Authors: A Vogler J M Lieb F J Ahlhelm Source Type: research

S3-Leitlinie „Diagnostik und Therapie biliärer Karzinome“ – Langversion 4.0
Z Gastroenterol. 2024 Feb;62(2):e213-e282. doi: 10.1055/a-2189-8567. Epub 2024 Feb 16.NO ABSTRACTPMID:38364849 | DOI:10.1055/a-2189-8567 (Source: Nuklearmedizin)
Source: Nuklearmedizin - February 16, 2024 Category: Radiology Authors: Sabrina Gro ß Michael Bitzer J örg Albert Susanne Bl ödt Judit Boda-Heggemann Thomas Brunner Reiner Caspari Enrico De Toni Frank Dombrowski Matthias Evert Markus Follmann Paul Freudenberger Cihan Gani Andreas Geier Eleni Gkika Martin G ötz Thomas Helm Source Type: research

S3-Leitlinie „Diagnostik und Therapie biliärer Karzinome“ – Kurzversion
Z Gastroenterol. 2024 Feb;62(2):231-260. doi: 10.1055/a-2189-8826. Epub 2024 Feb 16.NO ABSTRACTPMID:38364850 | DOI:10.1055/a-2189-8826 (Source: Nuklearmedizin)
Source: Nuklearmedizin - February 16, 2024 Category: Radiology Authors: Michael Bitzer Sabrina Gro ß J örg Albert Susanne Bl ödt Judit Boda-Heggemann Thomas Brunner Reiner Caspari Enrico De Toni Frank Dombrowski Matthias Evert Markus Follmann Paul Freudenberger Cihan Gani Andreas Geier Eleni Gkika Martin G ötz Thomas Helm Source Type: research

Orbital inflammatory diseases
Radiologie (Heidelb). 2024 Feb 16. doi: 10.1007/s00117-024-01271-7. Online ahead of print.ABSTRACTCLINICAL/METHODICAL ISSUE: Inflammatory orbital processes on imaging are often misinterpreted as tumors.STANDARD RADIOLOGICAL METHODS: Imaging comprises computed tomography (CT) and magnetic resonance imaging (MRI).ACHIEVEMENTS: Clinical and laboratory data play a crucial role in diagnosing many inflammatory orbital diseases. Radiological imaging provides a supporting but relevant role.PRACTICAL RECOMMENDATIONS: Clinical examination, including specialized ophthalmological examinations, laboratory diagnostics, and MRI are impor...
Source: Nuklearmedizin - February 16, 2024 Category: Radiology Authors: A Vogler J M Lieb F J Ahlhelm Source Type: research

Multisite Thrombosis in a Patient with Paroxysmal Nocturnal Hemoglobinuria
Hamostaseologie. 2024 Feb 9. doi: 10.1055/a-2231-5277. Online ahead of print.ABSTRACTParoxysmal nocturnal hemoglobinuria (PNH) is an extremely rare bone marrow disorder caused by acquired mutations in the phosphatidylinositol glycan class A gene, which lead to a partial or total loss of the cellular complement regulators CD55 and CD59.1 In addition to complement-mediated hemolysis and cytopenia, venous and arterial thromboses at multiple and/or unusual sites are a common complication and occur in up to 44% of patients in historic PNH cohorts.1 2.PMID:38335997 | DOI:10.1055/a-2231-5277 (Source: Nuklearmedizin)
Source: Nuklearmedizin - February 9, 2024 Category: Radiology Authors: Lennart Beckmann Tobias D Faizy Fabian Flottmann Jens Fiehler Carsten Bokemeyer Lennart Well Antonia Beitzen-Heineke Florian Langer Source Type: research

Multisite Thrombosis in a Patient with Paroxysmal Nocturnal Hemoglobinuria
Hamostaseologie. 2024 Feb 9. doi: 10.1055/a-2231-5277. Online ahead of print.ABSTRACTParoxysmal nocturnal hemoglobinuria (PNH) is an extremely rare bone marrow disorder caused by acquired mutations in the phosphatidylinositol glycan class A gene, which lead to a partial or total loss of the cellular complement regulators CD55 and CD59.1 In addition to complement-mediated hemolysis and cytopenia, venous and arterial thromboses at multiple and/or unusual sites are a common complication and occur in up to 44% of patients in historic PNH cohorts.1 2.PMID:38335997 | DOI:10.1055/a-2231-5277 (Source: Nuklearmedizin)
Source: Nuklearmedizin - February 9, 2024 Category: Radiology Authors: Lennart Beckmann Tobias D Faizy Fabian Flottmann Jens Fiehler Carsten Bokemeyer Lennart Well Antonia Beitzen-Heineke Florian Langer Source Type: research

Radiomics in Musculoskeletal Tumors
Semin Musculoskelet Radiol. 2024 Feb;28(1):49-61. doi: 10.1055/s-0043-1776428. Epub 2024 Feb 8.ABSTRACTSarcomas are heterogeneous rare tumors predominantly affecting the musculoskeletal (MSK) system. Due to significant variations in their natural history and variable response to conventional treatments, the discovery of novel diagnostic and prognostic biomarkers to guide therapeutic decision-making is an active and ongoing field of research. As new cellular, molecular, and metabolic biomarkers continue to be discovered, quantitative radiologic imaging is becoming increasingly important in sarcoma management. Radiomics offe...
Source: Nuklearmedizin - February 8, 2024 Category: Radiology Authors: Daniel Brandenberger Lawrence M White Source Type: research

Radiomics Analysis of Multiparametric PET/MRI for N- and M-Staging in Patients with Primary Cervical Cancer
CONCLUSION: M- and N-stage can be predicted based on isolated radiomics analyses of the primary tumor in cervical cancers, thus serving as a template for noninvasive tumor phenotyping and patient stratification using high-dimensional feature vectors extracted from multiparametric PET/MRI data.KEY POINTS: · Radiomics analysis based on multiparametric PET/MRI enables prediction of the metastatic status of cervical cancers. · Prediction of M-stage is superior to N-stage. · Multiparametric PET/MRI displays a valuable platform for radiomics analyses .PMID:38325362 | DOI:10.1055/a-2157-6867 (Source: Nuklearmedizin)
Source: Nuklearmedizin - February 7, 2024 Category: Radiology Authors: Lale Umutlu Felix Nensa Aydin Demircioglu Gerald Antoch Ken Herrmann Michael Forsting Johannes Stefan Grueneisen Source Type: research

18F-FDG PET/CT images of adult pulmonary blastoma: a case report
Nuklearmedizin. 2024 Feb 7. doi: 10.1055/a-2237-8775. Online ahead of print.NO ABSTRACTPMID:38325397 | DOI:10.1055/a-2237-8775 (Source: Nuklearmedizin)
Source: Nuklearmedizin - February 7, 2024 Category: Radiology Authors: Minhan Chen Yao Liu Source Type: research

Working Memory Training Responsiveness in Parkinson's Disease Is Not Determined by Cortical Thickness or White Matter Lesions
J Parkinsons Dis. 2024 Jan 22. doi: 10.3233/JPD-230367. Online ahead of print.ABSTRACTPatients with Parkinson's disease are highly vulnerable for cognitive decline. Thus, early intervention by means of working memory training (WMT) may be effective for the preservation of cognition. However, the influence of structural brain properties, i.e., cortical thickness and volume of white matter lesions on training responsiveness have not been studied. Here, behavioral and neuroimaging data of 46 patients with Parkinson's disease, 21 of whom engaged in home-based, computerized adaptive WMT, was analyzed. While cortical thickness a...
Source: Nuklearmedizin - January 26, 2024 Category: Radiology Authors: Kathrin Giehl Hendrik Theis Anja Ophey Jochen Hammes Paul Reker Carsten Eggers Gereon R Fink Elke Kalbe Thilo van Eimeren Source Type: research

Long-Term Follow-up and Mortality Rate of Patients of the Randomized Freeway Stent Study
CONCLUSION: The safety results presented support the recent conclusions that the use of paclitaxel technology does not lead to an increase in mortality. At the same time, the efficacy results clearly demonstrate that the potential benefits of drug-eluting balloon treatment are maintained over a 5-year period.PMID:38273128 | PMC:PMC10844456 | DOI:10.1007/s00270-023-03646-0 (Source: Nuklearmedizin)
Source: Nuklearmedizin - January 25, 2024 Category: Radiology Authors: Klaus Hausegger Wiebke Kurre Henrik Schr öder Johannes Dambach Stefanie Stahnke Christian Loewe Karl Sch ürmann Roman Fischbach Jochen Textor Stephan Sch äfer Stephan M üller-Hülsbeck Source Type: research

Determination of brain death using < sup > 99m < /sup > Tc-HMPAO scintigraphy and transcranial duplex sonography in a patient on veno-arterial ECMO
Neurol Res Pract. 2024 Jan 25;6(1):6. doi: 10.1186/s42466-023-00298-w.NO ABSTRACTPMID:38268033 | PMC:PMC10809543 | DOI:10.1186/s42466-023-00298-w (Source: Nuklearmedizin)
Source: Nuklearmedizin - January 24, 2024 Category: Radiology Authors: Albrecht G ünther Anke Werner Michael Fritzenwanger Martin Brauer Martin Freesmeyer P Christian Schulze Farid Salih Robert Drescher Source Type: research

Safety and Efficacy of Selective Internal Radionuclide Therapy with < sup > 90 < /sup > Y Glass Microspheres in Patients with Progressive Hepatocellular Carcinoma after the Failure of Repeated Transarterial Chemoembolization
This study aims to evaluate the safety and efficacy of SIRT with glass microspheres in patients with progressive HCC after repeated TACE who are not eligible for treatment with sorafenib. Forty-seven patients with progressive HCC after a median of three TACE sessions (range 2-14) underwent SIRT (3.5 ± 1.5 GBq; liver target dose 110-120 Gy). Toxicity was recorded 4 and 12 weeks after treatment and reported according to the Common Terminology Criteria for Adverse Events Version 5.0. Treatment response was assessed three months after SIRT using multiphase computed tomography and modified criteria in solid tumors (mRECIST). S...
Source: Nuklearmedizin - January 23, 2024 Category: Radiology Authors: Alexander Bellendorf Nicolai Mader Stefan P Mueller Samer Ezziddin Andreas Bockisch Hong Grafe Jan Best Juliane Goebel Thorsten D P öppel Amir Sabet Source Type: research

Incidental Papillary Thyroid Carcinoma Detected by Ga-68 DOTATATE PET/CT: A Rare Case Study and Clinical Considerations
Nuklearmedizin. 2024 Jan 23. doi: 10.1055/a-2238-4186. Online ahead of print.NO ABSTRACTPMID:38262470 | DOI:10.1055/a-2238-4186 (Source: Nuklearmedizin)
Source: Nuklearmedizin - January 23, 2024 Category: Radiology Authors: Adem Maman Source Type: research

Evaluation of risk analysis in treatment with unsealed radioactive substances in nuclear medicine
Nuklearmedizin. 2024 Jan 23. doi: 10.1055/a-2237-8639. Online ahead of print.ABSTRACTZIEL: Gemäß den Anforderungen des Strahlenschutzrechts hat vor der erstmaligen Behandlung mit radioaktiven Stoffen eine Risikoanalyse (RA) zu erfolgen. Die Durchführung einer solchen RA im Bereich der universitären Nuklearmedizin wurde 2020 publiziert 1. Entsprechend den gesetzlichen Bestimmungen hat eine Aktualisierung bei wesentlichen Änderungen von Teilprozessen zu erfolgen. Spätestens nach 3 Jahren wird eine Überprüfung empfohlen. Die Umsetzung und die Ergebnisse der Aktualisierung werden vorgestellt.METHODIK: Es erfolgten schr...
Source: Nuklearmedizin - January 23, 2024 Category: Radiology Authors: Robert Freudenberg David K ästner J örg Kotzerke Claudia Brogsitter Source Type: research