In situ management of late thrombosis of a renal graft vein in a patient with Cockett syndrome
We describe the case of a 57-year-old female patient who had a kidney transplant 32 years ago and developed a late thrombosis of the graft vein, accompanied by extensive thrombosis in the common femoral and iliac veins. Risk factors included severe malnutrition, chronic inflammation due to an anal fistula, and Cockett syndrome. The treatment consisted of mechanical thrombectomy of the iliac vein, placement of a stent in the common iliac vein, partial thromboaspiration of the renal vein thrombus with local thrombolysis, followed by systemic anticoagulation. With this approach, renal function fully recovered without major co...
Source: Nephrologie and Therapeutique - December 11, 2023 Category: Urology & Nephrology Authors: Jean Bertrand Frank Hammer Tom Darius Antoine Buemi Michel Mourad Arnaud Colle Nada Kanaan Arnaud Devresse Source Type: research
Smoking in chronic hemodialysis patients: prevalence and cardiovascular morbidity
CONCLUSION: Smoking is an important and modifiable cardiovascular risk factor in chronic hemodialysis patients.PMID:38073242 | DOI:10.1684/ndt.2023.57 (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - December 11, 2023 Category: Urology & Nephrology Authors: Wafaa Fadili Laila Lahlou Inass Laouad Source Type: research
Renal AA amyloidosis revealing extramedullary plasmocytoma
CONCLUSION: Extramedullary plasmacytoma is a rare tumour that may be associated with amyloidosis, usually type AL. To our knowledge, its association with AA amyloidosis has not been reported in the literature. Treatment is based on surgery combined with radiotherapy or chemotherapy.PMID:38073243 | DOI:10.1684/ndt.2023.54 (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - December 11, 2023 Category: Urology & Nephrology Authors: Amel Harzallah Hanen Abid Meriam Hajji Sahar Agrebi Fethi Ben Hamida Soumaya Chargui Ezzedine Abderrahim Source Type: research
Primary aldosteronism without hypertension: A case report and review of the literature
We describe the case of a patient who presented with hyperaldosteronism without arterial hypertension. She had been referred for consultation for persistent severe hypokalaemia despite oral KCl supplementation. The absence of hypertension had been proven by repeated clinical measurements and by ABPM. Hyperaldosteronism had been demonstrated by hormonal assays and catheterization of the adrenal veins. Abdominal CT revealed a left adrenal adenoma. Finally, the anatomopathological examination of the surgical specimen confirmed the adenoma. After the intervention, serum potassium normalized. The clinical case is completed by a...
Source: Nephrologie and Therapeutique - December 11, 2023 Category: Urology & Nephrology Authors: Yves Dimitrov Julien Ott Lisa Beguin Brieuc Muller Source Type: research
In situ management of late thrombosis of a renal graft vein in a patient with Cockett syndrome
We describe the case of a 57-year-old female patient who had a kidney transplant 32 years ago and developed a late thrombosis of the graft vein, accompanied by extensive thrombosis in the common femoral and iliac veins. Risk factors included severe malnutrition, chronic inflammation due to an anal fistula, and Cockett syndrome. The treatment consisted of mechanical thrombectomy of the iliac vein, placement of a stent in the common iliac vein, partial thromboaspiration of the renal vein thrombus with local thrombolysis, followed by systemic anticoagulation. With this approach, renal function fully recovered without major co...
Source: Nephrologie and Therapeutique - December 11, 2023 Category: Urology & Nephrology Authors: Jean Bertrand Frank Hammer Tom Darius Antoine Buemi Michel Mourad Arnaud Colle Nada Kanaan Arnaud Devresse Source Type: research
Smoking in chronic hemodialysis patients: prevalence and cardiovascular morbidity
CONCLUSION: Smoking is an important and modifiable cardiovascular risk factor in chronic hemodialysis patients.PMID:38073242 | DOI:10.1684/ndt.2023.57 (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - December 11, 2023 Category: Urology & Nephrology Authors: Wafaa Fadili Laila Lahlou Inass Laouad Source Type: research
Renal AA amyloidosis revealing extramedullary plasmocytoma
CONCLUSION: Extramedullary plasmacytoma is a rare tumour that may be associated with amyloidosis, usually type AL. To our knowledge, its association with AA amyloidosis has not been reported in the literature. Treatment is based on surgery combined with radiotherapy or chemotherapy.PMID:38073243 | DOI:10.1684/ndt.2023.54 (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - December 11, 2023 Category: Urology & Nephrology Authors: Amel Harzallah Hanen Abid Meriam Hajji Sahar Agrebi Fethi Ben Hamida Soumaya Chargui Ezzedine Abderrahim Source Type: research
Integrated clinical pharmacy activities into the pediatric kidney graft pathway
The objective is to evaluate the integration of clinical pharmacy activities into this care pathway. This feasibility study is divided into three stages: structuring, implementing and evaluation. In pre-transplant, immediate and remote post-transplant, interviews were proposed as well as the pharmaceutical analysis of medication prescriptions. In 8 months duration, 32 patients were included. All patients included in pre-transplant and immediate post-transplant benefited from the activities. At M0, all the prescriptions analyzed resulted in at least one problem detected. Half of the transplanted patients benefited from M1 m...
Source: Nephrologie and Therapeutique - December 7, 2023 Category: Urology & Nephrology Authors: Julie Martin Élise Jandot Valentine Br éant Anne-Laure Sellier-Leclerc Christelle Mouchoux Claire Lattard Justine Bacchetta Magali Larger Xavier Dode Delphine Hoegy Source Type: research
Cognitive impairment and the blood-brain barrier in chronic kidney disease: role of the uremic toxins
Nephrol Ther. 2023 Dec 7;19(7):1-9. doi: 10.1684/ndt.2023.51. Online ahead of print.ABSTRACTPatients with chronic kidney disease (CKD) have an increased risk of cognitive disorders, presenting as vascular dementia, compared with the general population. These cognitive disorders occur early during the course of the kidney disease and evolve in parallel with the decline in glomerular filtration rate. They affect 30 to 80 % of patients with stage 5 CKD. Kidney transplantation only partially improves cognitive impairment. In this narrative review, we summarize the epidemiology and recent clinical and experimental data on cogni...
Source: Nephrologie and Therapeutique - December 7, 2023 Category: Urology & Nephrology Authors: Micka ël Bobot Source Type: research
Impact of therapeutic education on the choice of renal replacement therapy. Moroccan monocentric experience
CONCLUSION: This study highlighted the insufficient level of patients' information about CKD and its treatment and allowed the patients to express their choice of their replacement therapy, which is a complicated process that must integrate the opinion of the nephrologist and the patient's preference to lead to an optimal organization of the therapeutic modality.PMID:38059845 | DOI:10.1684/ndt.2023.50 (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - December 7, 2023 Category: Urology & Nephrology Authors: Zineb Abouzid Kaoutar Sebti Naima Ouzeddoun Rabia Bayahia Loubna Benamar Source Type: research
Favorable evolution of severe paraquat poisoning. Treatment with gastric lavage, activated charcoal, cyclophosphamide + corticoids, and conventional daily hemodialysis: case study at the Franck Joly Hospital Center in french Guiana
We report the observations of two patients, having voluntarily ingested lethal doses of paraquat with suicidal intent, with an unfavorable prognostic score. The treatment consisted of gastric lavage, administration of activated charcoal, n-acetylcysteine and cyclophosphamide + methylprednisolone + dexamethasone. The installation of acute renal failure motivated the initiation of daily conventional hemodialysis (HD) over 10 to 14 days, with a favorable evolution. The following complications were recorded: anemia, bacteremia and deep vein thrombosis. These observations raise three questions in the treatment of paraquat intox...
Source: Nephrologie and Therapeutique - December 7, 2023 Category: Urology & Nephrology Authors: Arriel Makembi Bunkete Florence Fermigier S énan Dossou-Yovo J B Mombo Junior Sindani Camille Thorey Cr épin Kezza Franklin Samou Ir énée Djiconkpode Source Type: research
Integrated clinical pharmacy activities into the pediatric kidney graft pathway
The objective is to evaluate the integration of clinical pharmacy activities into this care pathway. This feasibility study is divided into three stages: structuring, implementing and evaluation. In pre-transplant, immediate and remote post-transplant, interviews were proposed as well as the pharmaceutical analysis of medication prescriptions. In 8 months duration, 32 patients were included. All patients included in pre-transplant and immediate post-transplant benefited from the activities. At M0, all the prescriptions analyzed resulted in at least one problem detected. Half of the transplanted patients benefited from M1 m...
Source: Nephrologie and Therapeutique - December 7, 2023 Category: Urology & Nephrology Authors: Julie Martin Élise Jandot Valentine Br éant Anne-Laure Sellier-Leclerc Christelle Mouchoux Claire Lattard Justine Bacchetta Magali Larger Xavier Dode Delphine Hoegy Source Type: research
Cognitive impairment and the blood-brain barrier in chronic kidney disease: role of the uremic toxins
Nephrol Ther. 2023 Dec 7;19(7):1-9. doi: 10.1684/ndt.2023.51. Online ahead of print.ABSTRACTPatients with chronic kidney disease (CKD) have an increased risk of cognitive disorders, presenting as vascular dementia, compared with the general population. These cognitive disorders occur early during the course of the kidney disease and evolve in parallel with the decline in glomerular filtration rate. They affect 30 to 80 % of patients with stage 5 CKD. Kidney transplantation only partially improves cognitive impairment. In this narrative review, we summarize the epidemiology and recent clinical and experimental data on cogni...
Source: Nephrologie and Therapeutique - December 7, 2023 Category: Urology & Nephrology Authors: Micka ël Bobot Source Type: research
Impact of therapeutic education on the choice of renal replacement therapy. Moroccan monocentric experience
CONCLUSION: This study highlighted the insufficient level of patients' information about CKD and its treatment and allowed the patients to express their choice of their replacement therapy, which is a complicated process that must integrate the opinion of the nephrologist and the patient's preference to lead to an optimal organization of the therapeutic modality.PMID:38059845 | DOI:10.1684/ndt.2023.50 (Source: Nephrologie and Therapeutique)
Source: Nephrologie and Therapeutique - December 7, 2023 Category: Urology & Nephrology Authors: Zineb Abouzid Kaoutar Sebti Naima Ouzeddoun Rabia Bayahia Loubna Benamar Source Type: research
Favorable evolution of severe paraquat poisoning. Treatment with gastric lavage, activated charcoal, cyclophosphamide + corticoids, and conventional daily hemodialysis: case study at the Franck Joly Hospital Center in french Guiana
We report the observations of two patients, having voluntarily ingested lethal doses of paraquat with suicidal intent, with an unfavorable prognostic score. The treatment consisted of gastric lavage, administration of activated charcoal, n-acetylcysteine and cyclophosphamide + methylprednisolone + dexamethasone. The installation of acute renal failure motivated the initiation of daily conventional hemodialysis (HD) over 10 to 14 days, with a favorable evolution. The following complications were recorded: anemia, bacteremia and deep vein thrombosis. These observations raise three questions in the treatment of paraquat intox...
Source: Nephrologie and Therapeutique - December 7, 2023 Category: Urology & Nephrology Authors: Arriel Makembi Bunkete Florence Fermigier S énan Dossou-Yovo J B Mombo Junior Sindani Camille Thorey Cr épin Kezza Franklin Samou Ir énée Djiconkpode Source Type: research
