PET imaging of retinal inflammation in mice exposed to blue light using [ < sup > 18 < /sup > F]-DPA-714
CONCLUSIONS: [18F]-DPA-714 micro-PET imaging might be a good method for evaluating early inflammatory status during retinal pathology.PMID:37859807 | PMC:PMC10584029 (Source: Molecular Vision)
Source: Molecular Vision - October 20, 2023 Category: Molecular Biology Authors: Yuan Chen Yixiang Zhou Xue Zhu Ge Yan Donghui Pan Lizhen Wang Min Yang Ke Wang Source Type: research
The impact of early RPE cell junction loss on VEGF, Ang-2, and TIMP secretion in vitro
CONCLUSIONS: These results suggest a correlation between loss of junctions, abnormal angiogenic protein secretion, and reduced OS phagocytosis. Furthermore, Ang-2 and TIMP-1 proteins might be beneficial targets for AMD treatments, and their roles in retinal diseases deserve further investigation.PMID:37859808 | PMC:PMC10584031 (Source: Molecular Vision)
Source: Molecular Vision - October 20, 2023 Category: Molecular Biology Authors: Chase Paterson Jamen Cannon Elizabeth Vargis Source Type: research
Collagen crosslinking impacts stromal wound healing and haze formation in a rabbit phototherapeutic keratectomy model
CONCLUSIONS: We showed that stromal haze formation and stromal stiffness is significantly increased following CXL, regardless of whether it is performed at or before the time of PTK. Further knowledge of the biophysical cues involved in determining corneal wound healing duration and outcomes will be important for understanding scarring following CXL and for the development of improved therapeutic options.PMID:37859806 | PMC:PMC10584030 (Source: Molecular Vision)
Source: Molecular Vision - October 20, 2023 Category: Molecular Biology Authors: Bret A Moore Iman Jalilian Soohyun Kim Makiko Mizutani Madison Mukai Connor Chang Alec M Entringer Kamesh Dhamodaran Vijay Krishna Raghunathan Leandro B C Teixeira Christopher J Murphy Sara M Thomasy Source Type: research
PET imaging of retinal inflammation in mice exposed to blue light using [ < sup > 18 < /sup > F]-DPA-714
CONCLUSIONS: [18F]-DPA-714 micro-PET imaging might be a good method for evaluating early inflammatory status during retinal pathology.PMID:37859807 | PMC:PMC10584029 (Source: Molecular Vision)
Source: Molecular Vision - October 20, 2023 Category: Molecular Biology Authors: Yuan Chen Yixiang Zhou Xue Zhu Ge Yan Donghui Pan Lizhen Wang Min Yang Ke Wang Source Type: research
The impact of early RPE cell junction loss on VEGF, Ang-2, and TIMP secretion in vitro
CONCLUSIONS: These results suggest a correlation between loss of junctions, abnormal angiogenic protein secretion, and reduced OS phagocytosis. Furthermore, Ang-2 and TIMP-1 proteins might be beneficial targets for AMD treatments, and their roles in retinal diseases deserve further investigation.PMID:37859808 | PMC:PMC10584031 (Source: Molecular Vision)
Source: Molecular Vision - October 20, 2023 Category: Molecular Biology Authors: Chase Paterson Jamen Cannon Elizabeth Vargis Source Type: research
