In vitro Azole Susceptibility Testing of Japanese Isolates of Itraconazole-Resistant Dermatophytes
Med Mycol J. 2023;64(4):103-105. doi: 10.3314/mmj.23-00005.ABSTRACTWe conducted antifungal susceptibility testing on itraconazole (ITCZ)-resistant isolates of Trichophyton interdigitale and Trichophyton rubrum collected from Japanese patients in 2021 and 2022. The aim of the present study was to determine the most effective drug against ITCZ-resistant strains of dermatophytes. In all isolates, the minimum inhibitory concentrations (MICs) were > 32 mg/l for ITCZ, < 0.03 to 0.5 mg/l for ravuconazole (RVCZ), and < 0.03 mg/l for efinaconazole (EFCZ), luliconazole (LUCZ), and terbinafine (TRBF). Thus, in tinea unguium ...
Source: Medical Mycology Journal - November 29, 2023 Category: Biology Authors: Honoka Nojo Junichiro Hiruma Hiromitsu Noguchi Masataro Hiruma Kazutoshi Harada Koichi Makimura Rui Kano Source Type: research
Invasive Malassezia Infections
Med Mycol J. 2023;64(4):79-83. doi: 10.3314/mmj.23-003.ABSTRACTThe Malassezia species are dimorphic fungi that require lipids such as olive oil for their growth. They are constituents of the normal human skin microbiota and can affix to the host or other surfaces through the establishment of biofilms. Malassezia species are accountable for superficial mycoses like folliculitis. Additionally, they are capable of causing invasive infections, such as of the bloodstream, in neonates and immunocompromised patients, albeit infrequently. Catheter-associated bloodstream infections in neonates are the most commonly reported invasiv...
Source: Medical Mycology Journal - November 29, 2023 Category: Biology Authors: Masato Tashiro Takahiro Takazono Koichi Izumikawa Source Type: research
2021 Epidemiological Survey of Dermatomycoses in Japan
Med Mycol J. 2023;64(4):85-94. doi: 10.3314/mmj.23-00008.ABSTRACTThis is a report of the results of the epidemiological survey on dermatomycoses conducted in 2021. A total of 9,442 patients with dermatomycosis were reported for one year. They include 8,151 (86.3%) with dermatophytosis, 796 (8.4%) with candidiasis, 484 (5.1%) with Malassezia infection, and 11 (0.1%) with deep cutaneous mycosis. In order, the most common types of dermatophytoses were tinea pedis (4,195 cases, 2,341 males and 1,854 females), tinea unguium (2,711 cases, 1,509 males and 1,202 females), tinea corporis (674 cases, 445 males and 229 females), tine...
Source: Medical Mycology Journal - November 29, 2023 Category: Biology Authors: Kaori Nakamura Tomoo Fukuda Source Type: research
Importance of Accurate Identification and Antifungal Susceptibility Testing of Aspergillus Species in Clinical Settings
In conclusion, accurate identification of Aspergillus spp. and ASTs are needed to carry out appropriate treatment. Moreover, we hope that these microbiological tests will be widely used in clinical laboratories to improve clinical practice.PMID:38030277 | DOI:10.3314/mmj.23-004 (Source: Medical Mycology Journal)
Source: Medical Mycology Journal - November 29, 2023 Category: Biology Authors: Keita Takeda Junko Suzuki Yuka Sasaki Akira Watanabe Katsuhiko Kamei Source Type: research
Isolation of Aspergillus udagawae in Canaliculitis: A Case Report
Med Mycol J. 2023;64(4):99-102. doi: 10.3314/mmj.23-00004.ABSTRACTAspergillus udagawae is a cryptic species of Aspergillus section Fumigati. Here, we report a case of canaliculitis with isolated A. udagawae. Fungal canaliculitis is a rare lacrimal disease, and its clinical features are poorly understood. The causative fungus was initially misclassified as Aspergillus thermomutatus by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) but was finally identified as A. udagawae by β-tubulin genetic analysis. The patient showed rapid improvement and did not experience relapse after dra...
Source: Medical Mycology Journal - November 29, 2023 Category: Biology Authors: Yuji Nishihara Takahito Nakamura Yuki Sakai Yumiko Ban Masato Tashiro Koichi Izumikawa Kei Kasahara Source Type: research
