Identification of Familial Infections Using Multilocus Microsatellite Typing in Tinea Corporis due to Microsporum canis
We report three cases of tinea corporis due to M. canis from a single household with a domestic cat as a pet. The cases included a woman in her thirties (mother), a girl in her teens (older sister), and a girl in her teens (younger sister). Following sudden hair loss in the domestic cat, annular erythema with pruritus and scales appeared on the face, neck, and limbs of the older sister, younger sister, and mother, sequentially; they subsequently visited our hospital. Potassium hydroxide direct microscopy revealed filamentous fungi on all three women. In addition, short-haired colonies with a white to yellowish-white color ...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Chiaki Takahashi Ryohei Asakura Ayaka Chaya Michi Ota Kazutoshi Harada Tatsuya Inukai Shigeki Nakamura Yasuki Hata Emiko Watanabe-Okada Source Type: research
Most Azole-Susceptible Isolates of Aspergillus fumigatus in Hokkaido, Japan are Clustered with Worldwide Strains That Do Not Have Tandem Repeats in Cyp51A Promoter
In this study, we analyzed Aspergillus fumigatus short tandem repeat patterns of 106 strains isolated from the outdoor air, clinical specimens, and king penguins (Aptenodytes patagonicus) with aspergillosis in Japan, and compared them with those of 668 strains from AfumID (including six isolates from Japan). The results showed that the isolates were classified into three major groups. Group II contained most of the azole-resistant strains with 34- and 46-bp tandem repeats in cyp51A promoter. As in our previous study, OKH50 and Env1 strains were classified in Group II. Most of the azole-susceptible strains obtained in Japan...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Takuya Fujiwara Megumi Itoh Naoya Matsumoto Yusuke Koshizaki Syunpei Saitou Kazutaka Yamada Takahito Toyotome Source Type: research
Skin Manifestations of Micafungin Breakthrough Disseminated Trichosporonosis in Acute Megakaryoblastic Leukemia
Med Mycol J. 2024;65(1):17-21. doi: 10.3314/mmj.23-00009.ABSTRACTDisseminated trichosporonosis is a rare fungal infection whose risk factors are hematological malignancies and neutropenia. Recently, breakthrough Trichosporon infections after administration of micafungin, the first-line systemic antifungal agent in compromised hosts, have been widely recognized. A man in his seventies about 1 month into chemotherapy for acute megakaryoblastic leukemia presented with a worsening fever and dyspnea. The patient was being administered with empirical micafungin therapy for suspected candidiasis. As the symptoms progressed, scatt...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Yukiro Matsumoto Sayuka Arakawa Ken Sadahira Tomotaka Sato Kazuto Yamazaki Shuhei Nishimoto Source Type: research
A Case of Tinea Faciei due to Trichophyton indotineae with Steroid Rosacea Related to Topical Over-The-Counter Drugs Purchased Outside of Japan
Med Mycol J. 2024;65(1):23-26. doi: 10.3314/mmj.23-00014.ABSTRACTA Filipino woman in her forties had facial erythema that was being self-treated with over-the-counter (OTC) drugs purchased outside of Japan. The drugs included clobetasol propionate, antibiotic, and antifungal components. Her facial erythema symptoms were worse during summertime. KOH direct examination of annular erythema was positive for fungal hyphae and negative for Demodex folliculorum. Fungal culture revealed Trichophyton indotineae based on internal transcribed spacer sequence analysis. Minimal inhibitory concentration for terbinafine was 0.06 µg/mL. ...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Norihito Fukada Hisashi Kobayashi Manabu Nakazono Keita Ohyachi Akinori Takeda Takashi Yaguchi Miyuki Okada Tomotaka Sato Source Type: research
A Silkworm Infection Model for Evaluating In Vivo Biofilm Formation by Pathogenic Fungi
Med Mycol J. 2024;65(1):7-12. doi: 10.3314/mmj.24.001.ABSTRACTExperimental animal models are necessary for research on infectious diseases. Generally, mammalian animals, such as mice, are used for infection experiments. However, there are ethical issues associated with conducting infection experiments in mammals. This has made it difficult to perform infection experiments with a large number of individuals. The invertebrate silkworm, Bombyx mori, is gaining attention as a model animal for infection experiments, and silkworm infection models with various pathogens have been established. This review provides information on t...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Yasuhiko Matsumoto Shintaro Eshima Sanae Kurakado Takashi Sugita Source Type: research
Identification of Familial Infections Using Multilocus Microsatellite Typing in Tinea Corporis due to Microsporum canis
We report three cases of tinea corporis due to M. canis from a single household with a domestic cat as a pet. The cases included a woman in her thirties (mother), a girl in her teens (older sister), and a girl in her teens (younger sister). Following sudden hair loss in the domestic cat, annular erythema with pruritus and scales appeared on the face, neck, and limbs of the older sister, younger sister, and mother, sequentially; they subsequently visited our hospital. Potassium hydroxide direct microscopy revealed filamentous fungi on all three women. In addition, short-haired colonies with a white to yellowish-white color ...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Chiaki Takahashi Ryohei Asakura Ayaka Chaya Michi Ota Kazutoshi Harada Tatsuya Inukai Shigeki Nakamura Yasuki Hata Emiko Watanabe-Okada Source Type: research
Most Azole-Susceptible Isolates of Aspergillus fumigatus in Hokkaido, Japan are Clustered with Worldwide Strains That Do Not Have Tandem Repeats in Cyp51A Promoter
In this study, we analyzed Aspergillus fumigatus short tandem repeat patterns of 106 strains isolated from the outdoor air, clinical specimens, and king penguins (Aptenodytes patagonicus) with aspergillosis in Japan, and compared them with those of 668 strains from AfumID (including six isolates from Japan). The results showed that the isolates were classified into three major groups. Group II contained most of the azole-resistant strains with 34- and 46-bp tandem repeats in cyp51A promoter. As in our previous study, OKH50 and Env1 strains were classified in Group II. Most of the azole-susceptible strains obtained in Japan...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Takuya Fujiwara Megumi Itoh Naoya Matsumoto Yusuke Koshizaki Syunpei Saitou Kazutaka Yamada Takahito Toyotome Source Type: research
Skin Manifestations of Micafungin Breakthrough Disseminated Trichosporonosis in Acute Megakaryoblastic Leukemia
Med Mycol J. 2024;65(1):17-21. doi: 10.3314/mmj.23-00009.ABSTRACTDisseminated trichosporonosis is a rare fungal infection whose risk factors are hematological malignancies and neutropenia. Recently, breakthrough Trichosporon infections after administration of micafungin, the first-line systemic antifungal agent in compromised hosts, have been widely recognized. A man in his seventies about 1 month into chemotherapy for acute megakaryoblastic leukemia presented with a worsening fever and dyspnea. The patient was being administered with empirical micafungin therapy for suspected candidiasis. As the symptoms progressed, scatt...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Yukiro Matsumoto Sayuka Arakawa Ken Sadahira Tomotaka Sato Kazuto Yamazaki Shuhei Nishimoto Source Type: research
A Case of Tinea Faciei due to Trichophyton indotineae with Steroid Rosacea Related to Topical Over-The-Counter Drugs Purchased Outside of Japan
Med Mycol J. 2024;65(1):23-26. doi: 10.3314/mmj.23-00014.ABSTRACTA Filipino woman in her forties had facial erythema that was being self-treated with over-the-counter (OTC) drugs purchased outside of Japan. The drugs included clobetasol propionate, antibiotic, and antifungal components. Her facial erythema symptoms were worse during summertime. KOH direct examination of annular erythema was positive for fungal hyphae and negative for Demodex folliculorum. Fungal culture revealed Trichophyton indotineae based on internal transcribed spacer sequence analysis. Minimal inhibitory concentration for terbinafine was 0.06 µg/mL. ...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Norihito Fukada Hisashi Kobayashi Manabu Nakazono Keita Ohyachi Akinori Takeda Takashi Yaguchi Miyuki Okada Tomotaka Sato Source Type: research
A Silkworm Infection Model for Evaluating In Vivo Biofilm Formation by Pathogenic Fungi
Med Mycol J. 2024;65(1):7-12. doi: 10.3314/mmj.24.001.ABSTRACTExperimental animal models are necessary for research on infectious diseases. Generally, mammalian animals, such as mice, are used for infection experiments. However, there are ethical issues associated with conducting infection experiments in mammals. This has made it difficult to perform infection experiments with a large number of individuals. The invertebrate silkworm, Bombyx mori, is gaining attention as a model animal for infection experiments, and silkworm infection models with various pathogens have been established. This review provides information on t...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Yasuhiko Matsumoto Shintaro Eshima Sanae Kurakado Takashi Sugita Source Type: research
Identification of Familial Infections Using Multilocus Microsatellite Typing in Tinea Corporis due to Microsporum canis
We report three cases of tinea corporis due to M. canis from a single household with a domestic cat as a pet. The cases included a woman in her thirties (mother), a girl in her teens (older sister), and a girl in her teens (younger sister). Following sudden hair loss in the domestic cat, annular erythema with pruritus and scales appeared on the face, neck, and limbs of the older sister, younger sister, and mother, sequentially; they subsequently visited our hospital. Potassium hydroxide direct microscopy revealed filamentous fungi on all three women. In addition, short-haired colonies with a white to yellowish-white color ...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Chiaki Takahashi Ryohei Asakura Ayaka Chaya Michi Ota Kazutoshi Harada Tatsuya Inukai Shigeki Nakamura Yasuki Hata Emiko Watanabe-Okada Source Type: research
Most Azole-Susceptible Isolates of Aspergillus fumigatus in Hokkaido, Japan are Clustered with Worldwide Strains That Do Not Have Tandem Repeats in Cyp51A Promoter
In this study, we analyzed Aspergillus fumigatus short tandem repeat patterns of 106 strains isolated from the outdoor air, clinical specimens, and king penguins (Aptenodytes patagonicus) with aspergillosis in Japan, and compared them with those of 668 strains from AfumID (including six isolates from Japan). The results showed that the isolates were classified into three major groups. Group II contained most of the azole-resistant strains with 34- and 46-bp tandem repeats in cyp51A promoter. As in our previous study, OKH50 and Env1 strains were classified in Group II. Most of the azole-susceptible strains obtained in Japan...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Takuya Fujiwara Megumi Itoh Naoya Matsumoto Yusuke Koshizaki Syunpei Saitou Kazutaka Yamada Takahito Toyotome Source Type: research
Skin Manifestations of Micafungin Breakthrough Disseminated Trichosporonosis in Acute Megakaryoblastic Leukemia
Med Mycol J. 2024;65(1):17-21. doi: 10.3314/mmj.23-00009.ABSTRACTDisseminated trichosporonosis is a rare fungal infection whose risk factors are hematological malignancies and neutropenia. Recently, breakthrough Trichosporon infections after administration of micafungin, the first-line systemic antifungal agent in compromised hosts, have been widely recognized. A man in his seventies about 1 month into chemotherapy for acute megakaryoblastic leukemia presented with a worsening fever and dyspnea. The patient was being administered with empirical micafungin therapy for suspected candidiasis. As the symptoms progressed, scatt...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Yukiro Matsumoto Sayuka Arakawa Ken Sadahira Tomotaka Sato Kazuto Yamazaki Shuhei Nishimoto Source Type: research
A Case of Tinea Faciei due to Trichophyton indotineae with Steroid Rosacea Related to Topical Over-The-Counter Drugs Purchased Outside of Japan
Med Mycol J. 2024;65(1):23-26. doi: 10.3314/mmj.23-00014.ABSTRACTA Filipino woman in her forties had facial erythema that was being self-treated with over-the-counter (OTC) drugs purchased outside of Japan. The drugs included clobetasol propionate, antibiotic, and antifungal components. Her facial erythema symptoms were worse during summertime. KOH direct examination of annular erythema was positive for fungal hyphae and negative for Demodex folliculorum. Fungal culture revealed Trichophyton indotineae based on internal transcribed spacer sequence analysis. Minimal inhibitory concentration for terbinafine was 0.06 µg/mL. ...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Norihito Fukada Hisashi Kobayashi Manabu Nakazono Keita Ohyachi Akinori Takeda Takashi Yaguchi Miyuki Okada Tomotaka Sato Source Type: research
A Silkworm Infection Model for Evaluating In Vivo Biofilm Formation by Pathogenic Fungi
Med Mycol J. 2024;65(1):7-12. doi: 10.3314/mmj.24.001.ABSTRACTExperimental animal models are necessary for research on infectious diseases. Generally, mammalian animals, such as mice, are used for infection experiments. However, there are ethical issues associated with conducting infection experiments in mammals. This has made it difficult to perform infection experiments with a large number of individuals. The invertebrate silkworm, Bombyx mori, is gaining attention as a model animal for infection experiments, and silkworm infection models with various pathogens have been established. This review provides information on t...
Source: Medical Mycology Journal - February 28, 2024 Category: Biology Authors: Yasuhiko Matsumoto Shintaro Eshima Sanae Kurakado Takashi Sugita Source Type: research
