Successful Endoscopic Submucosal Dissection Using Open Peroral Endoscopic Myotomy for Duodenal Neuroendocrine Tumor
Korean J Gastroenterol. 2024 Feb 25;83(2):61-64. doi: 10.4166/kjg.2023.145.ABSTRACTDuodenal neuroendocrine tumors (NETs) are subepithelial tumors that are difficult to remove endoscopically, particularly when located just beyond the pylorus. This paper reports a case of a successful endoscopic submucosal dissection (ESD) using open gastric peroral endoscopic myotomy (POEM) for a remnant duodenal NET detected after endoscopic mucosal resection (EMR). A 67-year-old male presented with a 5 mm remnant duodenal NET close to the pylorus after EMR for a duodenal polypoid lesion performed four months earlier. Duodenal ESD was perf...
Source: Korean J Gastroenter... - February 23, 2024 Category: Gastroenterology Authors: Ngoc Thi Bao Le Sang Jin Park Bong Ju Cho Min A Yang Jae Sun Song Won Dong Lee Myoung Jin Ju Jin Woong Cho Source Type: research
A Giant Gastric Perforation Occurring in the Normal Mucosa during Endoscopy in a Patient with Advanced Gastric Cancer
Korean J Gastroenterol. 2024 Feb 25;83(2):65-68. doi: 10.4166/kjg.2023.147.ABSTRACTThe incidence of giant gastric perforation occurring during upper gastrointestinal endoscopy is exceedingly rare. Gastric perforation can arise from excessive air insufflation and is more prevalent in elderly patients with atrophic gastritis. Although giant gastric mucosal lacerations during diagnostic endoscopy have occasionally been reported, there are few reports of giant gastric perforation. The authors experienced a giant gastric perforation occurring in the normal mucosa during endoscopy in an 81-year-old woman with advanced gastric ca...
Source: Korean J Gastroenter... - February 23, 2024 Category: Gastroenterology Authors: Cheol Min Lee Su Jin Kim Source Type: research
Microbiome and Biliary Tract Cancer
Korean J Gastroenterol. 2024 Jan 25;83(1):1-5. doi: 10.4166/kjg.2023.135.ABSTRACTBiliary tract cancers encompass a group of malignancies that affect the bile ducts and gallbladder and are associated with a poor prognosis, often due to late diagnosis and limited treatment options. The incidence of biliary tract cancer has been increasing gradually, underscoring the need for a better understanding of its pathogenesis and potential risk factors. Research suggests that biliary tract cancer may develop through a combination of genetic and epigenetic alterations, as well as environmental factors. The role of microbial exposure a...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Jin-Seok Park Source Type: research
Transcription Silencing and CpGs Hypermethylation as Therapeutic Gene Editing in Clinical Colorectal Adenocarcinoma Repression
CONCLUSIONS: miRNA-CGI-methylation led to the regression of Caco2 cell proliferation, suggesting the potential use of RNA silencing and DNA methylation in targeted gene therapy for colorectal cancer.PMID:38268163 | DOI:10.4166/kjg.2023.132 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Miqdam M Obaid Al-Jumaili Source Type: research
Rare Cause of Hematochezia in Children: Solitary Rectal Ulcer, Single Center Experience
CONCLUSIONS: This study is the first large series on Turkish children. An increased awareness of SRUS in children will increase the rate of early diagnosis and treatment, allowing remission in more patients.PMID:38268164 | DOI:10.4166/kjg.2023.093 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Fatma İlknur Varol Şükrü Güngör Mukadder Ay şe Selimoğlu Emine Şamdancı Source Type: research
A Case of Type II Achalasia Occurring in a Nonagenarian Diagnosed with Acute Food Impaction
We report a case of achalasia diagnosed by high-resolution esophageal manometry and timed barium esophagography after food material removal by endoscopy in a 95-year-old woman who visited the hospital due to sudden esophageal food impaction and was successfully treated by endoscopic balloon dilatation.PMID:38268165 | DOI:10.4166/kjg.2023.112 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Seong Hyun Koh Moo In Park Woo Hyuk Jung Kyoungwon Jung Sung Eun Kim Won Moon Seun Ja Park Source Type: research
Long-term Survivor of Unresectable Pancreatic Cancer Treated with Concurrent Chemoradiotherapy
Korean J Gastroenterol. 2024 Jan 25;83(1):28-32. doi: 10.4166/kjg.2023.140.ABSTRACTUndifferentiated carcinoma of the pancreas (UPC) is a rare, aggressive pancreatic cancer subtype. In addition, there is limited data on optimal management and patients tend to present with unresectable disease. This highlights the need to explore non-surgical treatments, such as chemotherapy and radiotherapy. In 2017, a 40-year-old male was diagnosed with UPC, presenting with a 6 cm mass in the pancreas, encasing the major arteries, indicative of a locally advanced stage. Histopathology confirmed UPC with osteoclast-like giant cells. After n...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Yun Je Song Jun-Ho Choi Source Type: research
A Curious Case of Primary Gastric Mucosal Melanoma
We present the case of a 58-year-old woman with complaints of abdominal pain, loss of appetite and weight. Esophagogastroduodenoscopy revealed a gastric mass and systemic imaging demonstrated widespread nodal and bilateral adrenal gland involvement. Histopathology of the gastric mass confirmed primary malignant mucosal melanoma of the stomach. The patient received three cycles of Nivolumab but did not respond, and thus, was then offered best supportive care. Although infrequent, mucosal melanoma can arise from the gastrointestinal tract, and in contrast to the cutaneous form, advanced disease usually has a dismal prognosis...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Zahabia Sohail Mirza Rameez Samar Neelam Jawed Qureshi Sidra Arshad Adeeba Zaki Source Type: research
Microbiome and Biliary Tract Cancer
Korean J Gastroenterol. 2024 Jan 25;83(1):1-5. doi: 10.4166/kjg.2023.135.ABSTRACTBiliary tract cancers encompass a group of malignancies that affect the bile ducts and gallbladder and are associated with a poor prognosis, often due to late diagnosis and limited treatment options. The incidence of biliary tract cancer has been increasing gradually, underscoring the need for a better understanding of its pathogenesis and potential risk factors. Research suggests that biliary tract cancer may develop through a combination of genetic and epigenetic alterations, as well as environmental factors. The role of microbial exposure a...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Jin-Seok Park Source Type: research
Transcription Silencing and CpGs Hypermethylation as Therapeutic Gene Editing in Clinical Colorectal Adenocarcinoma Repression
CONCLUSIONS: miRNA-CGI-methylation led to the regression of Caco2 cell proliferation, suggesting the potential use of RNA silencing and DNA methylation in targeted gene therapy for colorectal cancer.PMID:38268163 | DOI:10.4166/kjg.2023.132 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Miqdam M Obaid Al-Jumaili Source Type: research
Rare Cause of Hematochezia in Children: Solitary Rectal Ulcer, Single Center Experience
CONCLUSIONS: This study is the first large series on Turkish children. An increased awareness of SRUS in children will increase the rate of early diagnosis and treatment, allowing remission in more patients.PMID:38268164 | DOI:10.4166/kjg.2023.093 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Fatma İlknur Varol Şükrü Güngör Mukadder Ay şe Selimoğlu Emine Şamdancı Source Type: research
A Case of Type II Achalasia Occurring in a Nonagenarian Diagnosed with Acute Food Impaction
We report a case of achalasia diagnosed by high-resolution esophageal manometry and timed barium esophagography after food material removal by endoscopy in a 95-year-old woman who visited the hospital due to sudden esophageal food impaction and was successfully treated by endoscopic balloon dilatation.PMID:38268165 | DOI:10.4166/kjg.2023.112 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Seong Hyun Koh Moo In Park Woo Hyuk Jung Kyoungwon Jung Sung Eun Kim Won Moon Seun Ja Park Source Type: research
Long-term Survivor of Unresectable Pancreatic Cancer Treated with Concurrent Chemoradiotherapy
Korean J Gastroenterol. 2024 Jan 25;83(1):28-32. doi: 10.4166/kjg.2023.140.ABSTRACTUndifferentiated carcinoma of the pancreas (UPC) is a rare, aggressive pancreatic cancer subtype. In addition, there is limited data on optimal management and patients tend to present with unresectable disease. This highlights the need to explore non-surgical treatments, such as chemotherapy and radiotherapy. In 2017, a 40-year-old male was diagnosed with UPC, presenting with a 6 cm mass in the pancreas, encasing the major arteries, indicative of a locally advanced stage. Histopathology confirmed UPC with osteoclast-like giant cells. After n...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Yun Je Song Jun-Ho Choi Source Type: research
A Curious Case of Primary Gastric Mucosal Melanoma
We present the case of a 58-year-old woman with complaints of abdominal pain, loss of appetite and weight. Esophagogastroduodenoscopy revealed a gastric mass and systemic imaging demonstrated widespread nodal and bilateral adrenal gland involvement. Histopathology of the gastric mass confirmed primary malignant mucosal melanoma of the stomach. The patient received three cycles of Nivolumab but did not respond, and thus, was then offered best supportive care. Although infrequent, mucosal melanoma can arise from the gastrointestinal tract, and in contrast to the cutaneous form, advanced disease usually has a dismal prognosis...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Zahabia Sohail Mirza Rameez Samar Neelam Jawed Qureshi Sidra Arshad Adeeba Zaki Source Type: research
Microbiome and Biliary Tract Cancer
Korean J Gastroenterol. 2024 Jan 25;83(1):1-5. doi: 10.4166/kjg.2023.135.ABSTRACTBiliary tract cancers encompass a group of malignancies that affect the bile ducts and gallbladder and are associated with a poor prognosis, often due to late diagnosis and limited treatment options. The incidence of biliary tract cancer has been increasing gradually, underscoring the need for a better understanding of its pathogenesis and potential risk factors. Research suggests that biliary tract cancer may develop through a combination of genetic and epigenetic alterations, as well as environmental factors. The role of microbial exposure a...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Jin-Seok Park Source Type: research
