A Case of Type II Achalasia Occurring in a Nonagenarian Diagnosed with Acute Food Impaction
We report a case of achalasia diagnosed by high-resolution esophageal manometry and timed barium esophagography after food material removal by endoscopy in a 95-year-old woman who visited the hospital due to sudden esophageal food impaction and was successfully treated by endoscopic balloon dilatation.PMID:38268165 | DOI:10.4166/kjg.2023.112 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Seong Hyun Koh Moo In Park Woo Hyuk Jung Kyoungwon Jung Sung Eun Kim Won Moon Seun Ja Park Source Type: research

Long-term Survivor of Unresectable Pancreatic Cancer Treated with Concurrent Chemoradiotherapy
Korean J Gastroenterol. 2024 Jan 25;83(1):28-32. doi: 10.4166/kjg.2023.140.ABSTRACTUndifferentiated carcinoma of the pancreas (UPC) is a rare, aggressive pancreatic cancer subtype. In addition, there is limited data on optimal management and patients tend to present with unresectable disease. This highlights the need to explore non-surgical treatments, such as chemotherapy and radiotherapy. In 2017, a 40-year-old male was diagnosed with UPC, presenting with a 6 cm mass in the pancreas, encasing the major arteries, indicative of a locally advanced stage. Histopathology confirmed UPC with osteoclast-like giant cells. After n...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Yun Je Song Jun-Ho Choi Source Type: research

A Curious Case of Primary Gastric Mucosal Melanoma
We present the case of a 58-year-old woman with complaints of abdominal pain, loss of appetite and weight. Esophagogastroduodenoscopy revealed a gastric mass and systemic imaging demonstrated widespread nodal and bilateral adrenal gland involvement. Histopathology of the gastric mass confirmed primary malignant mucosal melanoma of the stomach. The patient received three cycles of Nivolumab but did not respond, and thus, was then offered best supportive care. Although infrequent, mucosal melanoma can arise from the gastrointestinal tract, and in contrast to the cutaneous form, advanced disease usually has a dismal prognosis...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Zahabia Sohail Mirza Rameez Samar Neelam Jawed Qureshi Sidra Arshad Adeeba Zaki Source Type: research

Microbiome and Biliary Tract Cancer
Korean J Gastroenterol. 2024 Jan 25;83(1):1-5. doi: 10.4166/kjg.2023.135.ABSTRACTBiliary tract cancers encompass a group of malignancies that affect the bile ducts and gallbladder and are associated with a poor prognosis, often due to late diagnosis and limited treatment options. The incidence of biliary tract cancer has been increasing gradually, underscoring the need for a better understanding of its pathogenesis and potential risk factors. Research suggests that biliary tract cancer may develop through a combination of genetic and epigenetic alterations, as well as environmental factors. The role of microbial exposure a...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Jin-Seok Park Source Type: research

Transcription Silencing and CpGs Hypermethylation as Therapeutic Gene Editing in Clinical Colorectal Adenocarcinoma Repression
CONCLUSIONS: miRNA-CGI-methylation led to the regression of Caco2 cell proliferation, suggesting the potential use of RNA silencing and DNA methylation in targeted gene therapy for colorectal cancer.PMID:38268163 | DOI:10.4166/kjg.2023.132 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Miqdam M Obaid Al-Jumaili Source Type: research

Rare Cause of Hematochezia in Children: Solitary Rectal Ulcer, Single Center Experience
CONCLUSIONS: This study is the first large series on Turkish children. An increased awareness of SRUS in children will increase the rate of early diagnosis and treatment, allowing remission in more patients.PMID:38268164 | DOI:10.4166/kjg.2023.093 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Fatma İlknur Varol Şükrü Güngör Mukadder Ay şe Selimoğlu Emine Şamdancı Source Type: research

A Case of Type II Achalasia Occurring in a Nonagenarian Diagnosed with Acute Food Impaction
We report a case of achalasia diagnosed by high-resolution esophageal manometry and timed barium esophagography after food material removal by endoscopy in a 95-year-old woman who visited the hospital due to sudden esophageal food impaction and was successfully treated by endoscopic balloon dilatation.PMID:38268165 | DOI:10.4166/kjg.2023.112 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Seong Hyun Koh Moo In Park Woo Hyuk Jung Kyoungwon Jung Sung Eun Kim Won Moon Seun Ja Park Source Type: research

Long-term Survivor of Unresectable Pancreatic Cancer Treated with Concurrent Chemoradiotherapy
Korean J Gastroenterol. 2024 Jan 25;83(1):28-32. doi: 10.4166/kjg.2023.140.ABSTRACTUndifferentiated carcinoma of the pancreas (UPC) is a rare, aggressive pancreatic cancer subtype. In addition, there is limited data on optimal management and patients tend to present with unresectable disease. This highlights the need to explore non-surgical treatments, such as chemotherapy and radiotherapy. In 2017, a 40-year-old male was diagnosed with UPC, presenting with a 6 cm mass in the pancreas, encasing the major arteries, indicative of a locally advanced stage. Histopathology confirmed UPC with osteoclast-like giant cells. After n...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Yun Je Song Jun-Ho Choi Source Type: research

A Curious Case of Primary Gastric Mucosal Melanoma
We present the case of a 58-year-old woman with complaints of abdominal pain, loss of appetite and weight. Esophagogastroduodenoscopy revealed a gastric mass and systemic imaging demonstrated widespread nodal and bilateral adrenal gland involvement. Histopathology of the gastric mass confirmed primary malignant mucosal melanoma of the stomach. The patient received three cycles of Nivolumab but did not respond, and thus, was then offered best supportive care. Although infrequent, mucosal melanoma can arise from the gastrointestinal tract, and in contrast to the cutaneous form, advanced disease usually has a dismal prognosis...
Source: Korean J Gastroenter... - January 25, 2024 Category: Gastroenterology Authors: Zahabia Sohail Mirza Rameez Samar Neelam Jawed Qureshi Sidra Arshad Adeeba Zaki Source Type: research

Infectious Gastric Diseases Other than < em > Helicobacter < /em >
This article aims to contribute to the rapid diagnosis and treatment of rare stomach infections beyond Helicobacter pylori in real clinical situations.PMID:38129996 | DOI:10.4166/kjg.2023.139 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - December 22, 2023 Category: Gastroenterology Authors: Hyemin Jo Cheol Min Shin Source Type: research

Association Preoperative Protein Adequacy and Post Elective Laparotomy Surgical Site Infection
CONCLUSIONS: The preoperative protein adequacy and albumin levels were strongly related to predicting the post-elective laparotomy SSI.PMID:38129997 | DOI:10.4166/kjg.2023.103 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - December 22, 2023 Category: Gastroenterology Authors: Davie Muhamad Nurul Ratna Mutu Manikam Ridho Ardhi Syaiful Source Type: research

Leucovorin-induced Hypersensitivity Reaction in a Patient with Metastatic Colorectal Cancer Treated with Cetuximab Plus FOLFOX Chemotherapy: A Case Report
This report aims to investigate the clinical presentation, diagnosis, and management of leucovorin induced HSRs. A 60-year-old female developed generalized edema, dyspnea, and facial redness during cetuximab plus FOLFOX chemotherapy administered for management of metastatic colorectal cancer. Because HSRs induced by oxaliplatin are commonly reported, we initially presumed an oxaliplatin-induced HSR. However, despite undergoing oxaliplatin desensitization, HSRs persisted, and they were still observed when leucovorin was administered without oxaliplatin. The patient was diagnosed with leucovorin-induced HSR and underwent leu...
Source: Korean J Gastroenter... - December 22, 2023 Category: Gastroenterology Authors: Minna Kim Dong Hyun Kim Jong Yoon Lee Young-Hee Nam Jong Hoon Lee Source Type: research

Plug-Assisted Retrograde Transvenous Obliteration for the Treatment of Duodenal Variceal Bleeding - A Case Report and Literature Review
Korean J Gastroenterol. 2023 Dec 25;82(6):295-299. doi: 10.4166/kjg.2023.105.ABSTRACTDuodenal varices are uncommon complications of portal hypertension. Although duodenal variceal bleeding is infrequent, it is a life-threatening condition with a high mortality rate. Non-surgical methods for duodenal variceal bleeding include endoscopic band ligation, endoscopic sclerotherapy, transjugular intrahepatic portosystemic shunt, and retrograde transvenous obliteration. On the other hand, an optimal treatment strategy for this rare condition has not been established. A 38-year-old male with a history of alcoholic liver cirrhosis p...
Source: Korean J Gastroenter... - December 22, 2023 Category: Gastroenterology Authors: Kyung Kyu Lee Jae Yong Park Woo Sun Choi Young Youn Cho Source Type: research

Unique Case of Severe Sepsis and Acute Respiratory Failure in the Setting of Aseptic Epiploic Appendagitis of the Descending Colon
Korean J Gastroenterol. 2023 Dec 25;82(6):300-303. doi: 10.4166/kjg.2023.111.ABSTRACTEpiploic appendagitis (EA) is an uncommon intraabdominal pathology resulting in transient, localized pain. The condition is caused by ischemia of one of the epiploic appendages, which are distributed axially along the length of the colon. EA is often mistaken for other more common etiologies of an acute abdomen. Generally, the patients experience focal abdominal pain with no further symptoms or laboratory abnormalities. The authors encountered a 79-year-old male with severe sepsis and acute respiratory failure requiring intubation. He reco...
Source: Korean J Gastroenter... - December 22, 2023 Category: Gastroenterology Authors: Nathaniel J Leavitt Usman S Kazi Ryan Cromwell Fagunkumar Modi Source Type: research

Small Bowel Variceal Bleeding in Patients with Liver Cirrhosis Treated with Transarterial Embolization: Case Series
Korean J Gastroenterol. 2023 Dec 25;82(6):304-309. doi: 10.4166/kjg.2023.116.ABSTRACTSmall bowel variceal bleeding is a rare cause of gastrointestinal hemorrhage, with clinical manifestations ranging from asymptomatic incidental findings to life-threatening conditions. The diagnosis and management of small bowel bleeding are challenging because of the localization of the lesion and the difficulty of the procedure. Trans-arterial embolization (TAE) is a secure and straightforward method for treating ectopic varices. On the other hand, there have been limited local studies on the outcomes of TAE for patients with small bowel...
Source: Korean J Gastroenter... - December 22, 2023 Category: Gastroenterology Authors: Boram Seo Ju Ho Lee Eun Jeong Jang Sang Woon Park Ju Sang Park Sang Jong Park Sang-Jung Kim Jae Woo Yeon Ah Young Lee Jun-Young Seo Source Type: research