Comparison of Glecaprevir/Pibrentasvir and Sofosbuvir/Ledipasvir in Patients with Hepatitis C Virus Genotype 1 and 2 in South Korea
CONCLUSIONS: Both regimens had similar treatment completion rates, effectiveness, and safety profiles. Therefore, the SOF/LDV regimen can also be considered a viable DAA for the treatment of patients with genotype 1 or 2 chronic hepatitis C.PMID:38522854 | DOI:10.4166/kjg.2023.141 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Hyun Deok Shin Il Han Song Sae Hwan Lee Hong Soo Kim Tae Hee Lee Hyuk Soo Eun Seok Hyun Kim Byung Seok Lee Hee Bok Chae Seok Hwan Kim Myung Joon Song Soon Yeong Ko Suk Bae Kim Source Type: research
Life-threatening Gastrointestinal Bleeding from a Dieulafoy's Lesion in the Duodenum: A Case Report
Korean J Gastroenterol. 2024 Mar 25;83(3):119-122. doi: 10.4166/kjg.2024.014.ABSTRACTDieulafoy's lesion is a rare cause of gastrointestinal bleeding, accounting for approximately 1-2% of all cases of gastrointestinal bleeding. Dieulafoy's lesion usually occurs in the lesser curvature of the stomach within six centimeters of the gastroesophageal junction. On the other hand, extragastric Dieulafoy's lesions are uncommon. Diagnosing an extragastric Dieulafoy's lesion by endoscopy can be challenging because of its small size and obscure location. The key elements for an accurate diagnosis include heightened awareness and a car...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Jun Hyuk Son Source Type: research
Severe Liver Dysfunction after Donor Lymphocyte Infusion for Relapsed Multiple Myeloma
Korean J Gastroenterol. 2024 Mar 25;83(3):123-126. doi: 10.4166/kjg.2024.007.ABSTRACTDonor lymphocyte infusion (DLI) is performed to augment an anti-tumor immune response or ensure donor stem cells remain engrafted following allogeneic stem cell transplantation but may induce graft-versus-host disease (GVHD) involving skin, intestine, and liver. Although hepatic involvement of GVHD can manifest as mild to severe hepatitis, few reports have mentioned acute severe liver dysfunction with encephalopathy. We experienced a case of acute severe liver dysfunction with semicoma after DLI in a patient with relapsed multiple myeloma ...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Tae-Hoon No Nae-Yun Heo Seung Ha Park Joon Hyuk Choi Junghwan Lee Sung Nam Lim Seon Yang Park Source Type: research
Obesity and Upper Gastrointestinal Diseases
Korean J Gastroenterol. 2024 Mar 25;83(3):81-86. doi: 10.4166/kjg.2024.015.ABSTRACTObesity increases gastroesophageal reflux disease through several factors. As a result, Barrett's esophagus, esophageal adenocarcinoma, and gastroesophageal junctional gastric cancer are increasing. Existing studies usually defined obesity by body mass index and analyzed the correlation. Recently, more studies have shown that central obesity is a more important variable in upper gastrointestinal diseases related to gastroesophageal reflux. Studies have reported that weight loss is effective in reducing gastroesophageal reflux symptoms. Obesi...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Younghee Choe Source Type: research
Dietary Management of Obesity
In conclusion, diet therapy stands as a pivotal element in the management of obesity, providing a personalized and comprehensive approach to weight control. By combining evidence-based dietary strategies with behavioral modifications and consistent support, healthcare professionals can enable individuals to attain and sustain a healthier weight, thereby reducing related health risks.PMID:38522851 | DOI:10.4166/kjg.2024.004 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Sang Hoon Lee San Ha Kim Sung Chul Park Source Type: research
Current State of Pharmacotherapy in Obesity
Korean J Gastroenterol. 2024 Mar 25;83(3):94-101. doi: 10.4166/kjg.2024.016.ABSTRACTThe prevalence of obesity with various complications is increasing rapidly in Korea. Although lifestyle modification is fundamental in obesity treatment, more effective treatment tools are required. Many advances in obesity treatment have been reported recently, including lifestyle modifications and pharmacological, endoscopic, and surgical treatments. Drugs with proven long-term efficacy and safety are preferred because management for obesity treatment is a long-term process. Currently, four medications are available for long-term use in K...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Won Jun Kim Source Type: research
Comparison of the Clinical Outcomes of Esophagectomy and Concurrent Chemoradiotherapy in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma
CONCLUSIONS: These results showed no significant difference in survival between the definitive CCRT and surgery as the initial treatment. Nevertheless, larger prospective studies will be needed because of the retrospective nature and small number of patients in this study.PMID:38522853 | DOI:10.4166/kjg.2023.100 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Myung Hun Lee Moo In Park Ju Won Lee Kyoungwon Jung Jae Hyun Kim Sung Eun Kim Won Moon Seun Ja Park Source Type: research
Comparison of Glecaprevir/Pibrentasvir and Sofosbuvir/Ledipasvir in Patients with Hepatitis C Virus Genotype 1 and 2 in South Korea
CONCLUSIONS: Both regimens had similar treatment completion rates, effectiveness, and safety profiles. Therefore, the SOF/LDV regimen can also be considered a viable DAA for the treatment of patients with genotype 1 or 2 chronic hepatitis C.PMID:38522854 | DOI:10.4166/kjg.2023.141 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Hyun Deok Shin Il Han Song Sae Hwan Lee Hong Soo Kim Tae Hee Lee Hyuk Soo Eun Seok Hyun Kim Byung Seok Lee Hee Bok Chae Seok Hwan Kim Myung Joon Song Soon Yeong Ko Suk Bae Kim Source Type: research
Life-threatening Gastrointestinal Bleeding from a Dieulafoy's Lesion in the Duodenum: A Case Report
Korean J Gastroenterol. 2024 Mar 25;83(3):119-122. doi: 10.4166/kjg.2024.014.ABSTRACTDieulafoy's lesion is a rare cause of gastrointestinal bleeding, accounting for approximately 1-2% of all cases of gastrointestinal bleeding. Dieulafoy's lesion usually occurs in the lesser curvature of the stomach within six centimeters of the gastroesophageal junction. On the other hand, extragastric Dieulafoy's lesions are uncommon. Diagnosing an extragastric Dieulafoy's lesion by endoscopy can be challenging because of its small size and obscure location. The key elements for an accurate diagnosis include heightened awareness and a car...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Jun Hyuk Son Source Type: research
Severe Liver Dysfunction after Donor Lymphocyte Infusion for Relapsed Multiple Myeloma
Korean J Gastroenterol. 2024 Mar 25;83(3):123-126. doi: 10.4166/kjg.2024.007.ABSTRACTDonor lymphocyte infusion (DLI) is performed to augment an anti-tumor immune response or ensure donor stem cells remain engrafted following allogeneic stem cell transplantation but may induce graft-versus-host disease (GVHD) involving skin, intestine, and liver. Although hepatic involvement of GVHD can manifest as mild to severe hepatitis, few reports have mentioned acute severe liver dysfunction with encephalopathy. We experienced a case of acute severe liver dysfunction with semicoma after DLI in a patient with relapsed multiple myeloma ...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Tae-Hoon No Nae-Yun Heo Seung Ha Park Joon Hyuk Choi Junghwan Lee Sung Nam Lim Seon Yang Park Source Type: research
Obesity and Upper Gastrointestinal Diseases
Korean J Gastroenterol. 2024 Mar 25;83(3):81-86. doi: 10.4166/kjg.2024.015.ABSTRACTObesity increases gastroesophageal reflux disease through several factors. As a result, Barrett's esophagus, esophageal adenocarcinoma, and gastroesophageal junctional gastric cancer are increasing. Existing studies usually defined obesity by body mass index and analyzed the correlation. Recently, more studies have shown that central obesity is a more important variable in upper gastrointestinal diseases related to gastroesophageal reflux. Studies have reported that weight loss is effective in reducing gastroesophageal reflux symptoms. Obesi...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Younghee Choe Source Type: research
Dietary Management of Obesity
In conclusion, diet therapy stands as a pivotal element in the management of obesity, providing a personalized and comprehensive approach to weight control. By combining evidence-based dietary strategies with behavioral modifications and consistent support, healthcare professionals can enable individuals to attain and sustain a healthier weight, thereby reducing related health risks.PMID:38522851 | DOI:10.4166/kjg.2024.004 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Sang Hoon Lee San Ha Kim Sung Chul Park Source Type: research
Current State of Pharmacotherapy in Obesity
Korean J Gastroenterol. 2024 Mar 25;83(3):94-101. doi: 10.4166/kjg.2024.016.ABSTRACTThe prevalence of obesity with various complications is increasing rapidly in Korea. Although lifestyle modification is fundamental in obesity treatment, more effective treatment tools are required. Many advances in obesity treatment have been reported recently, including lifestyle modifications and pharmacological, endoscopic, and surgical treatments. Drugs with proven long-term efficacy and safety are preferred because management for obesity treatment is a long-term process. Currently, four medications are available for long-term use in K...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Won Jun Kim Source Type: research
Comparison of the Clinical Outcomes of Esophagectomy and Concurrent Chemoradiotherapy in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma
CONCLUSIONS: These results showed no significant difference in survival between the definitive CCRT and surgery as the initial treatment. Nevertheless, larger prospective studies will be needed because of the retrospective nature and small number of patients in this study.PMID:38522853 | DOI:10.4166/kjg.2023.100 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Myung Hun Lee Moo In Park Ju Won Lee Kyoungwon Jung Jae Hyun Kim Sung Eun Kim Won Moon Seun Ja Park Source Type: research
Comparison of Glecaprevir/Pibrentasvir and Sofosbuvir/Ledipasvir in Patients with Hepatitis C Virus Genotype 1 and 2 in South Korea
CONCLUSIONS: Both regimens had similar treatment completion rates, effectiveness, and safety profiles. Therefore, the SOF/LDV regimen can also be considered a viable DAA for the treatment of patients with genotype 1 or 2 chronic hepatitis C.PMID:38522854 | DOI:10.4166/kjg.2023.141 (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Hyun Deok Shin Il Han Song Sae Hwan Lee Hong Soo Kim Tae Hee Lee Hyuk Soo Eun Seok Hyun Kim Byung Seok Lee Hee Bok Chae Seok Hwan Kim Myung Joon Song Soon Yeong Ko Suk Bae Kim Source Type: research
