Neurobiology of Implicit and Explicit Bias: Implications for Clinicians.
Authors: Reihl KM, Hurley RA, Taber KH PMID: 26488489 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 23, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Effect of Repetitive Transcranial Magnetic Stimulation on Psychomotor Retardation in Major Depression: A Pilot Feasibility Study.
Authors: Thomas-Ollivier V, Deschamps T, Bulteau S, Le Gall F, Pichot A, Valriviere P, Vachon H, Sauvaget A Abstract This pilot study investigated the feasibility of a comprehensive battery of tests assessing psychomotor retardation after a 3-week protocol of repetitive transcranial magnetic stimulation for depression. In addition to the beneficial effect of this treatment on depression, the results showed positive changes in psychomotor retardation. PMID: 26449267 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 10, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Clinical Implications of the National Institute of Neurological Disorders and Stroke Criteria for Diagnosing Psychosis in Parkinson's Disease.
Authors: Gordon PC, Kauark RB, Costa CD, de Oliveira MO, Godinho FL, Rocha MS Abstract The effect of psychotic symptoms in Parkinson's disease (PD) is variable among patients, and different methods to assess psychosis may yield conflicting results. A sample of 102 patients with a diagnosis of idiopathic PD underwent neurological, psychiatric, and neuropsychological assessment. Participants were divided into three groups: those who met DSM criteria for psychotic disorder, those who had psychotic symptoms but did not meet DSM criteria, and those without any psychotic symptoms. The first group had significantly worse ...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 10, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Suicide and Chronic Traumatic Encephalopathy.
This article aims to discuss the critical issues and literature relating to these possible relationships. PMID: 26449269 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 10, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Pathophysiological Role of HERV-W in Schizophrenia.
Authors: Aftab A, Shah AA, Hashmi AM Abstract Schizophrenia is a neuropsychiatric disorder of complex etiology. Human endogenous retroviruses (HERVs) have been presented as possible candidates explaining the connections between the genetic, infectious, neurodevelopmental, and neuroinflammatory aspects of schizophrenia, with the human endogenous retrovirus type W family (HERV-W) showing the greatest evidence of association. Studies have identified retroviral nucleotide sequences, envelope and capsid proteins, and elevated transcription of HERV-W elements in CSF, blood, and brain samples from individuals with schizop...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 28, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Predictors of Recovery From Posttraumatic Amnesia.
This study examined the predictive value of variables known early in the course of posttraumatic amnesia (PTA) on length of PTA and functional outcome of acute rehabilitation. Forty patients with traumatic brain injury who had PTA at admission for acute inpatient rehabilitation were included (29 men and 11 women; aged 18-91 years). This article presents the characteristics of the patients who came out of PTA and those who did not emerge during the acute inpatient rehabilitation stay. These data suggest that the location of the lesion (specifically, parietal lobe lesions) and initial cognitive scores are helpful in prognost...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 28, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Predictors of Hypomania During Ventral Capsule/Ventral Striatum Deep Brain Stimulation.
Authors: Widge AS, Licon E, Zorowitz S, Corse A, Arulpragasam AR, Camprodon JA, Cusin C, Eskandar EN, Deckersbach T, Dougherty DD Abstract Deep brain stimulation (DBS) of the ventral capsule/ventral striatum (VC/VS) is a novel therapy for neuropsychiatric disorders. Hypomania is a known complication of VC/VS DBS, but who is at risk is less understood. Factors such as family history, combined with details of DBS programming, might quantify that risk. The authors performed an iterative modeling procedure on a VC/VS DBS patient registry to identify key predictors. Hypomania was less common for men and for patients sti...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 28, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Mixed-Handedness in Identical Twins Discordant for Combat Exposure in Vietnam: Relationship to Posttraumatic Stress Disorder.
This study evaluated the degree of mixed-handedness in predominantly right-handed Vietnam combat veteran twins and their identical, combat-unexposed cotwins. The "high-risk" cotwins of combat veterans with combat-related posttraumatic stress disorder (PTSD) had more mixed-handedness (i.e., less right-handedness) than the "low-risk" cotwins of combat veterans without PTSD. Self-reported combat exposure in combat-exposed twins was a mediator of the association between handedness in their unexposed cotwins and PTSD in the twins themselves. We conclude that mixed-handedness is a familial risk factor for com...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 28, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

White Matter Abnormalities in Autism and Unaffected Siblings.
This study was conducted to identify a potential neuroendophenotype for autism using diffusion tensor imaging. Whole-brain, voxel-based analysis of fractional anisotropy was conducted in 50 children: 19 with autism, 20 unaffected siblings, and 11 controls. Relative to controls, participants with autism exhibited bilateral reductions in fractional anisotropy across association, commissure, and projection fibers. The most severely affected tracts included the uncinate fasciculus, forceps minor, and inferior fronto-occipital fasciculus. Unaffected siblings also exhibited reductions in fractional anisotropy, albeit less severe...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 28, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Clinical and Neurophysiologic Characteristics of Unprovoked Seizures in Patients Diagnosed With Dementia.
Authors: Sarkis RA, Dickerson BC, Cole AJ, Chemali ZN Abstract Seizures are a common comorbid condition in patients with dementia, but their characteristics have been poorly described. The authors performed a retrospective chart review using ICD-9 diagnosis codes consistent with seizures and with dementia. Seventy-seven patients were identified. Average age at onset was 68.1 years for cognitive symptoms, 71.5 years for dementia, and 73.9 years for seizures. Seizures preceded or followed cognitive symptoms (4.3 years before and 18.7 years after). At last follow-up, 12% of patients continued to have seizures. Finding...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 28, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Multigenerational Positive Family History of Psychiatric Disorders Is Associated With a Poor Prognosis in Bipolar Disorder.
Authors: Post RM, Altshuler L, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Leverich GS, Nolen WA Abstract The authors assessed how family history loading affected the course of illness in patients from the United States. A total of 676 outpatients with bipolar disorder from the United States rated their illness and provided a parental and grandparental history of mood disorder, substance abuse, and other clinical conditions. A positive family history for each illness was associated with almost all of the seven poor prognosis factors established in the study (abuse in childhood, early onset, a...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 12, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Preinjury Emotional-Behavioral Functioning of Children With Lingering Problems After Mild Traumatic Brain Injury.
This study aimed to characterize preinjury emotional-behavioral functioning in pediatric patients with lingering problems after mild traumatic brain injury (TBI). The clinical case series design included 278 patients 8-17 years old. Parents retrospectively rated children's preinjury emotional-behavioral functioning on a broadband questionnaire. The rate of clinically significant preinjury anxiety was elevated compared with national norms. The number of previous TBIs was associated with clinically significant preinjury externalizing problems, suggesting a link between externalizing disorders and mild TBI exposure. Premorbid...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 12, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Research Trends in the Neuropsychiatry Literature Since the New Millennium.
This study confirms that neuropsychiatry is a quintessentially clinical discipline with a continuing focus on phenomenological aspects, possibly reflecting the centrality of clinical observations to the diagnostic process. PMID: 26258491 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 12, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Pathological Laughter and Crying and Psychiatric Comorbidity After Traumatic Brain Injury.
This study aimed to identify the occurrence of PLC in the first year after TBI and to determine whether there is a relationship between PLC and other clinical features or demographics. Subjects who sustained a first-time TBI were recruited from acute trauma units and were assessed at 3, 6, and 12 months after TBI. Rates of PLC at 3, 6, and 12 months after TBI were 21.4%, 17.5%, and 15.5%, respectively. Patients with PLC had higher percentages of psychiatric diagnoses, including personality changes, depressive disorders, and mood disorders secondary to a general medical condition, as well as higher rates of posttraumatic st...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 12, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Neurobiology of Adult ADHD: Emerging Evidence for Network Dysfunctions.
Authors: Jadidian A, Hurley RA, Taber KH PMID: 26222966 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Pilot Study of Neurological Soft Signs and Depressive and Postconcussive Symptoms During Recovery From Mild Traumatic Brain Injury (mTBI).
Authors: Greenberg MS, Wood NE, Spring JD, Gurvits TV, Nagurney JT, Zafonte RD, Pitman RK Abstract Neurological soft signs (NSSs) tap into a variety of perceptual, motor, and cognitive functions. The authors administered a battery of NSSs serially to a group of 14 pilot patients recruited from an emergency room after they experienced a mild traumatic brain injury. Patients were seen within 96 hours after injury, and again 30 and 90 days later. Measures of balance, mood, and postconcussive symptoms and impairment were also obtained. NSSs and balance improved across visits. Across visits, NSSs and balance were not si...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Correction.
Authors: PMID: 26222968 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

A Temporal Link Between Epileptiform Brain Activity, Schizotypy, and Pedophilia.
Authors: Poeppl TB, Peytard J, Langguth B PMID: 26222969 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Improvement of Central Sleep Apneas Following Ventricular Shunt for Normal Pressure Hydrocephalus.
Authors: Oliveira MF, Nacif SR, Castellano O, Sousa UO, Rotta JM, Pinto FC PMID: 26222970 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Transient Global Amnesia as a Presenting Manifestation of Cerebral Venous Thrombosis.
Authors: Sharma RC, Kainth A, Sharma S PMID: 26222971 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Treatment of Huntington Disease and Comorbid Trichotillomania With Aripiprazole.
Authors: Howard AK, Krishnamoorthy A, Leavitt BR, Raymond LA, Weissman CR PMID: 26222972 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Pharmacotherapy in Bipolar Depression Comorbid With Parkinson's Disease: A Case Report.
Authors: Wang JK, Lee HC PMID: 26222973 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Paroxetine-Related Adult-Onset Tic Disorder: A Presentation of Primary Progressive Multiple Sclerosis.
Authors: Mendonça MD, Leitão C, Barahona-Corrêa B, Lampreia T PMID: 26222974 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Catatonia After Glioblastoma Multiforme in a Patient With Schizophrenia: The Importance of Establishing Etiology.
Authors: Lyra A, Cordeiro Q, Shiozawa P PMID: 26222975 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Ictal Asomatognosia With Illusory Limb Movement Secondary to Dominant Parietal Lobe Lesion.
Authors: Ting SK, Yong KP, Hameed S PMID: 26222976 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Anti-Ma2 Antibody Encephalitis Manifesting as Cognitive Impairment and Psychosis.
Authors: Park MS, Bae JH, Jeong HB, Kim JM, Kwon OS, Youn YC, Ahn SW PMID: 26222977 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 31, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Neural Correlates of Intolerance of Uncertainty in Clinical Disorders.
In conclusion, studies focusing on the neural correlates of this construct are sparse, and findings are inconsistent across disorders. Future research should identify neural correlates of intolerance of uncertainty in more detail. This may unravel the neurobiology of a wide variety of clinical disorders and pave the way for novel therapeutic targets. PMID: 26185902 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 18, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Natural History of Poststroke Apathy During Acute Rehabilitation.
Authors: Kennedy JM, Granato DA, Goldfine AM Abstract To better understand the natural history of poststroke apathy, the authors tested 96 patients undergoing acute rehabilitation for stroke using the Apathy Inventory. A total of 28% of patients had apathy. Their Apathy Inventory scores improved a mean of 1 point by week 2 and 2 points by week 3, with the majority of patients remaining apathetic at discharge. Apathy severity correlated with aphasia, weakness, and impaired cognition but did not correlate with depression. These findings suggest that acute rehabilitation is an optimal setting for clinical trials for p...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 18, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Social Anxiety Level in Adult Patients With Epilepsy and Their First-Degree Cohabiting Relatives.
This study investigated state and trait anxiety, depression, and social fear and avoidance levels in 48 adult patients with epilepsy and 48 family members, compared with 43 healthy control subjects, using the Beck Anxiety Inventory, the Beck Depression Inventory, the State-Trait Anxiety Inventory, and the Liebowitz Social Anxiety Scale. The results suggested that the patients and their first-degree relatives had higher levels of depression, state and trait anxiety, and avoidance compared with healthy subjects. The mothers of patients with epilepsy had the highest level of depression and anxiety. PMID: 26185904 [PubMed ...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 18, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Personality Change Due to Traumatic Brain Injury in Children and Adolescents: Neurocognitive Correlates.
This study aimed to examine neurocognitive correlates of PC. The sample included 177 children 5-14 years old with traumatic brain injury who were enrolled from consecutive admissions to five trauma centers. Patients were followed up prospectively at baseline and at 6 months, and they were assessed with semistructured psychiatric interviews. Injury severity, socioeconomic status, and neurocognitive function (measures of attention, processing speed, verbal memory, IQ, verbal working memory, executive function, naming/reading, expressive language, motor speed, and motor inhibition) were assessed with standardized instruments....
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 18, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Reliability and Validity of Proposed DSM-5 ADHD Symptoms in a Clinical Sample of Adults.
Authors: Matte B, Rohde LA, Turner JB, Fisher PW, Shen S, Bau CH, Nigg JT, Grevet EH Abstract The DSM-5 ADHD and Disruptive Behaviors Work Group proposed two major changes for diagnosis of attention deficit hyperactivity disorder (ADHD) in adults: 1) inclusion of four new impulsivity symptoms and 2) reduction in the number of symptoms required for assigning an ADHD diagnosis. In this case-control study, the performance of these modifications was assessed in a clinical sample of 133 adult subjects (68 ADHD cases and 65 non-ADHD control subjects). The proposed new impulsivity symptoms for adults do not improve ADHD d...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 14, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Preliminary Findings Supporting Insula Metabolic Activity as a Predictor of Outcome to Psychotherapy and Medication Treatments for Depression.
Authors: Dunlop BW, Kelley ME, McGrath CL, Craighead WE, Mayberg HS Abstract A putative right anterior insula metabolism biomarker predictive of treatment outcomes was retrospectively applied to 30 depressed psychotherapy-or escitalopram-treated nonremitters who entered combination treatment. Patients whose added treatment matched the biomarker-indicated treatment remitted more often than biomarker-mismatched patients. PMID: 26067435 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 14, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Irritability in a Prospective Cohort of Huntington's Disease Mutation Carriers.
Authors: Bouwens JA, van Duijn E, van der Mast RC, Roos RA, Giltay EJ Abstract A key neuropsychiatric symptom of Huntington's disease, irritability, contributes to a decline in functioning and to great distress in both patients and their caregivers. To identify mutation carriers prone to the development of irritability, this study aimed to investigate the course and temporal relationships between irritability and other neuropsychiatric symptoms. A cohort of 90 mutation carriers was followed for 2 years. Using the Irritability Scale, the incidence of irritability was 23%, whereas irritability persisted in 70% of the...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 14, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Verbal Fluency as a Rapid Screening Test for Cognitive Impairment in Early Parkinson's Disease.
Authors: Torralva T, Laffaye T, Báez S, Gleichgerrcht E, Bruno D, Chade A, Ibañez A, Manes F, Gershanik O, Roca M Abstract The phonological verbal fluency test can act as a fast screening test to detect cognitive deficits in neurological conditions. In the present study, its utility in the detection of executive deficits in patients with early Parkinson's disease is demonstrated. PMID: 26067437 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 14, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Reward Sensitivity (Behavioral Activation System), Cognitive, and Metacognitive Control in Gambling Behavior: Evidences From Behavioral, Feedback-Related Negativity, and P300 Effect.
Authors: Balconi M, Finocchiaro R, Canavesio Y Abstract The present research explored the main factors able to influence the subjects' choices in the case of decisions and distinguish between high- and low-risk decisions. Behavioral responses (Iowa Gambling Task [IGT]), meta-cognitive strategy, and event-related potential (feedback-related negativity [FRN] and P300) effects were used as predictive markers of gambling behavior. Behavioral activation system (BAS)-reward measure was applied to distinguish between high-BAS and low-BAS. It was found that higher-BAS opted in favor of the immediate reward, with a concomit...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 14, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

From Semantic to Social Deficits: Dysfunction of the Nondominant Posterior Perisylvian Area in Schizophrenia.
This article reviews recent evidence supporting heritable deficits in a circuit necessary for appropriate naming of emotions and mental states in others, centered at the temporoparietal junction of the nondominant hemisphere. The clinical implications of this model are discussed, including the potential use of rehabilitation techniques oriented to recognition and naming of emotions and mental states as a necessary step for social rehabilitation. PMID: 26067439 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 14, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Pharmacological management of persistent hostility and aggression in persons with schizophrenia spectrum disorders: a systematic review.
Authors: Victoroff J, Coburn K, Reeve A, Sampson S, Shillcutt S Abstract The incidence of aggressive behaviors is higher among persons with schizophrenia spectrum disorders (SSDs) than among persons without such disorders. This phenomenon represents a risk to the well-being of patients, their families, and society. The authors undertook a systematic review of the English language literature to determine the efficacy of neuropharmacological agents for the management of hostility and aggression among persons with SSDs. The search combined findings from the Medline, EMBASE, and PsycINFO databases. Ninety-two full text...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Behavioral health symptoms associated with chronic traumatic encephalopathy: a critical review of the literature and recommendations for treatment and research.
Authors: Antonius D, Mathew N, Picano J, Hinds A, Cogswell A, Olympia J, Brooks T, DiGiacomo M, Baker J, Willer B, Leddy J Abstract Chronic traumatic encephalopathy (CTE) is a neurodegenerative syndrome that has been linked to serious psychiatric symptoms, including depression, aggression, and suicidal behavior. This review critically examines the extant research on the behavioral manifestations of CTE and concludes that the paucity of longitudinal prospective studies on CTE, combined with a lack of research-accepted diagnostic criteria for identifying individuals who are considered at risk for CTE, makes it diffic...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Conventional SPECT Versus 3D Thresholded SPECT Imaging in the Diagnosis of ADHD: A Retrospective Study.
Authors: Schneider H, Thornton JF, Freeman MA, McLean MK, van Lierop MJ, Schneider J Abstract Brain single photon emission CT (SPECT) scans indirectly show functional activity via measurement of regional cerebral blood flow. In conventional SPECT scans, the typical tomographic slices are produced. In three-dimensional thresholded SPECT scans, pixels representing activity below a certain threshold are discarded. A retrospective analysis of 427 patients shows that three-dimensional thresholded SPECT scans yield a sensitivity for predicting clinical attention deficit hyperactivity disorder of 54% [95% confidence inter...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

The Association of BDNF Val66Met Polymorphism With Trait Anxiety in Panic Disorder.
Authors: Konishi Y, Tanii H, Otowa T, Sasaki T, Kaiya H, Okada M, Okazaki Y Abstract Recent studies indicate that early-onset panic disorder (PD) may show distinct clinical characteristics. The authors compared patients with early-onset PD, patients with late-onset PD, and healthy control subjects in terms of brain-derived neurotrophic factor (BDNF), the Val66Met polymorphism, State-Trait Anxiety Inventory (STAI) scores, and the Revised NEO Personality Inventory. In patients with early-onset PD, the STAI-T score was high in the Met/Met group, whereas the STAI-T score of the Val/Val group tended to be higher for hea...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Diagnostic Utility of the International HIV Dementia Scale for HIV-Associated Neurocognitive Impairment and Disorder in South Africa.
Authors: Goodkin K, Hardy DJ, Singh D, Lopez E Abstract Studies in sub-Saharan Africa indicate that most HIV seropositive persons have HIV-associated neurocognitive disorder (HAND). HAND diagnosis is facilitated by specific screening. Seventy participants were recruited from an HIV voluntary counseling and testing clinic in Durban, South Africa. The diagnostic utility of the International HIV Dementia Scale (IHDS) was analyzed using a receiver operating characteristic (ROC) model. The ROC analysis comparing any HAND diagnosis (based on two neuropsychological tests) versus no diagnosis was statistically significant,...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Longitudinal evaluation of the psychomotor syndrome in schizophrenia.
Authors: Docx L, Sabbe B, Fransen E, Bervoets C, Hulstijn W, Van Den Bossche MJ, Vermeylen S, Temmerman A, Morsel A, Morrens M Abstract Little is known about the longitudinal course of psychomotor signs and symptoms after illness onset in schizophrenia. Therefore, a 1-year follow-up study was conducted in which patients with schizophrenia were assessed three times with an extensive battery of psychomotor rating scales and tests. The syndromic structure of psychomotor symptoms was also studied. In accordance with a neurodevelopmental view on schizophrenia, psychomotor functioning was found to remain stable or improv...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Erratum.
Authors: PMID: 26037859 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Erratum.
Authors: PMID: 26037860 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Decreased dopamine concentrations in the frontal cortex after ablative surgeries in patients exhibiting self-injurious behavior: a microdialysis study.
Authors: Liu A, Li A, Zhang H, Zhang Z Abstract The authors examined brain neurochemistry in four patients with mental retardation with self-injurious behaviors after ablative surgeries. The authors found that surgeries in the human limbic system can alter dopamine levels in the frontal cortex over a 36-hour period. PMID: 26037861 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Erratum.
Authors: PMID: 26037862 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

The effect of transient ischemic attack clinical pathway.
CONCLUSIONS: Implementation of TIA CP could reduce the length of stay, the proportion of medication cost, and optimize the structure of hospital expense, thus making best use of medical resources and improve the quality of TIA medical care. PMID: 26037863 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

The science of neuropsychiatry: past, present, and future.
This article reviews the history and development of neuropsychiatry in the occidental world, suggesting that the science of neuropsychiatry could optimize for the diagnosis, monitoring, and treatment of behavioral, cognitive, and so-called mental disorders. PMID: 26037864 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Do patients with tourette syndrome jump to conclusions?
Authors: Eddy CM, Cavanna AE Abstract Tourette syndrome can be associated with impulsive and compulsive symptoms and changes in reasoning. This controlled study revealed that patients with Tourette syndrome exhibit a tendency toward jumping to conclusions on a probabilistic reasoning task, with implications for social cognition. PMID: 26037865 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

In appreciation.
Authors: PMID: 26037866 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2015 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research