What Is the Role of a Specialist Assessment Clinic for FND? Lessons From Three National Referral Centers.
CONCLUSIONS: FND specialty clinics have an important role in ensuring correct diagnosis and appropriate treatment. Most patients with motor FND require specialized neurophysiotherapy. Patients readily accepted an integrated neuropsychiatric approach. Close collaboration between FND clinics and acute neurology facilities might improve early detection of FND and could improve outcomes. PMID: 31587627 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 9, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Impaired Action Control in Patients With Functional Movement Disorders.
CONCLUSIONS: These results suggest that two forms of inhibitory control, selective impulse inhibition and global action cancelation, are impaired in patients with FMD, independent of slowing on go reaction times. Improved understanding of action control in FMD may help in the development of new diagnostic and therapeutic strategies. PMID: 31587628 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 9, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Risk of Misdiagnosing Chronic Traumatic Encephalopathy in Men With Depression.
CONCLUSIONS: The clinical problems attributed to CTE, such as depression, suicidality, anxiety, anger control problems, and headaches, co-occurred in this sample of men with depression from the general population-illustrating that these problems are not specific or unique to CTE. More research is needed to determine whether depression is, in fact, a clinical subtype of CTE. PMID: 31587629 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 9, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Internal Versus External Frame of Reference in Functional Movement Disorders.
CONCLUSIONS: Patients with FMD exhibited high "within our control" internal general and health-specific frame of reference. LOC had no influence on quality of life or disease severity in this patient population. PMID: 31564234 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 1, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Delusions Without Hallucinations After Midbrain Infarction.
Authors: Sakamoto K, Yokoi K, Kawakatsu S, Kobayashi R, Kunihiro K, Okada O, Sato Y, Otani K, Hirayama K PMID: 31564235 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 1, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Outpatient Physical Therapy for Functional Neurological Disorder: A Preliminary Feasibility and Naturalistic Outcome Study in a U.S. Cohort.
CONCLUSIONS: This preliminary, retrospective cohort study demonstrated that treatment adherence to a U.S.-based outpatient physical therapy program was associated with clinical improvement. Prospective observational and randomized controlled trials are needed to further optimize physical therapy for patients with functional motor symptoms in the outpatient setting. PMID: 31564236 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 1, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Koro Delusion in Mild Cognitive Impairment Due to Alzheimer's Disease.
Authors: Tau M, Masurkar AV PMID: 31530117 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 20, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Serum and CSF Anti-NMDAR Antibody Testing in Psychiatry.
CONCLUSIONS: These findings suggest that traditional psychiatric care may be appropriate for patients with isolated psychiatric symptoms who have positive serum NMDAR testing when CSF is negative and there are no key clinical features such as cognitive deficits, catatonia, speech disturbance, and antipsychotic sensitivity. However, if these key features are present, a trial of immunomodulatory treatment should be considered with repeated examination of CSF for neuronal antibodies. PMID: 31530118 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 20, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Loss of Consciousness and Altered Mental State as Predictors of Functional Recovery Within 6 Months Following Mild Traumatic Brain Injury.
Authors: Roy D, Peters ME, Everett AD, Leoutsakos JS, Yan H, Rao V, T Bechtold K, Sair HI, Van Meter T, Falk H, Vassila A, Hall A, Ofoche U, Akbari F, Lyketsos C, Korley F Abstract OBJECTIVE: The authors tested the hypothesis that a combination of loss of consciousness (LOC) and altered mental state (AMS) predicts the highest risk of incomplete functional recovery within 6 months after mild traumatic brain injury (mTBI), compared with either condition alone, and that LOC alone is more strongly associated with incomplete recovery, compared with AMS alone. METHODS: Data were analyzed from 407 patients with mTBI f...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 20, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Predisposing Risk Factors for Functional Limb Weakness: A Case-Control Study.
Authors: Stone J, Warlow C, Deary I, Sharpe M Abstract OBJECTIVE: Functional limb weakness is a common symptom of functional neurological disorder. Few controlled studies have examined possible predisposing factors to determine their specificity for this symptom. METHODS: In this prospective case-control study, patients with functional limb weakness (
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 31, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

A Systematic Review of Neuropsychiatric Symptoms and Functional Capacity in Huntington's Disease.
CONCLUSIONS: There is some evidence that depression and apathy are associated with decreased functional capacity in Huntington's disease. Other neuropsychiatric symptoms have been infrequently examined. Further knowledge of the relationships between neuropsychiatric symptoms and functional capacity will identify areas for intervention and improvement of outcomes in patients with Huntington's disease. PMID: 31466515 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 31, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Motivational Interviewing Techniques to Improve Psychotherapy Adherence and Outcomes for Patients With Psychogenic Nonepileptic Seizures.
Authors: Tolchin B, Baslet G, Martino S, Suzuki J, Blumenfeld H, Hirsch LJ, Altalib H, Dworetzky BA Abstract Psychogenic nonepileptic seizures (PNES) are a highly disabling disorder frequently encountered by neurologists, psychiatrists, and emergency medicine physicians. There is accumulating evidence for the efficacy of psychological therapies, yet the majority of patients do not complete treatment. A range of health care system-based, clinician-based, and patient-based barriers to treatment exists, including stigma, poor clinician-patient communication, and patient ambivalence about the diagnosis and treatment of...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 31, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Functional Motor Symptoms in Parkinson's Disease and Functional Parkinsonism: A Systematic Review.
CONCLUSIONS: Findings suggest a possible relationship between PD and FP. Clinicians should keep in mind the possibility of functional symptoms in PD patients. PMID: 31466517 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 31, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Outpatient CBT for Motor Functional Neurological Disorder and Other Neuropsychiatric Conditions: A Retrospective Case Comparison.
CONCLUSIONS: Improvements in physical and psychological functioning were similar for patients with mFND and patients with ONP who were treated in a specialist CBT clinic. This study provides evidence that CBT is feasible and effective for some patients with mFND. PMID: 31466518 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 31, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Characterizing the Link Between Glial Activation and Changed Functional Connectivity in National Football League Players Using Multimodal Neuroimaging.
CONCLUSIONS: Further study of the clinical significance of this altered pattern of interregional connectivity in active and recently retired NFL players is needed. PMID: 31394988 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 11, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Pilot Study of An Intracranial Electroencephalography Biomarker of Depressive Symptoms in Epilepsy.
CONCLUSIONS: These finding suggest, for the first time, that neural features across circuits involved in epilepsy may distinguish patients who have depressive symptoms from those who do not. Larger studies are required to validate these findings and to assess their diagnostic utility in MDD. PMID: 31394989 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 11, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Message Framing and the Willingness to Pursue Behavioral Therapy: A Study of People With Migraine.
CONCLUSIONS: Findings revealed that message framing was not associated with willingness to seek behavioral therapy for migraine. PMID: 31394990 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - August 11, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Fantastic Thinking and Frontal Cerebrovascular Disease.
Authors: Parand L, Niu K, Yerstein O, Mendez MF PMID: 31331214 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Fibromyalgia: Centralized Pain Processing and Neuroimaging.
Authors: Richard JY, Hurley RA, Taber KH PMID: 31322995 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 21, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Apathy in Obsessive-Compulsive Disorder and Its Psychological Correlates: Comparison With Individuals With Schizophrenia.
CONCLUSIONS: These findings suggest that motivational deficits could play a central role in disability caused by OCD. Similar to other mental disorders, various psychological factors, including depression, defeatist beliefs, and dysexecutive functioning, are involved in apathetic manifestations. However, the fact that depression is the variable most associated with apathy indicates that apathetic symptoms in patients with OCD must be considered mainly as secondary rather than primary symptoms. PMID: 31266408 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 5, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Distress Tolerance and Symptom Severity as Mediators of Symptom Validity Failure in Veterans With PTSD.
CONCLUSIONS: PTSD severity was associated with failing a memory-based PVT but not an attention-based PVT. Neither PVT was associated with distress tolerance or PTSD diagnosis. SVT failure was associated with PTSD diagnosis, poor distress tolerance, and high symptomatology. For veterans with PTSD, difficulty managing negative emotional states may contribute to symptom overreporting. This may reflect exaggeration or an inability to tolerate stronger negative affect, rather than a "cry for help." PMID: 31266409 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 5, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

The Prevalence of Cavum Septum Pellucidum in Mental Disorders Revealed by MRI: A Meta-Analysis.
CONCLUSIONS: The meta-regression with predefined covariance indicated that imaging parameters were not associated with the heterogeneity among original studies; however, the mean age of enrolled subjects was identified as a possible source of heterogeneity. No publication bias was found. PMID: 31266410 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 5, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Management of Insomnia and Anxiety in Myasthenia Gravis.
Authors: Jordan H, Ortiz N Abstract Myasthenia gravis is a neuroimmunological disorder leading to skeletal muscle weakness. Common symptoms of the disease, such as anxiety, depression, and insomnia, can cause significant distress in patients. Unfortunately, selecting an appropriate medication for treatment of psychiatric comorbidities can prove to be challenging for providers given the unique pharmacologic constraints that myasthenia gravis presents. The authors present the following clinical vignette and accompanying discussion in an attempt to highlight the special considerations that must be taken into account w...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 12, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

An Opioid-Related Amnestic Syndrome With Persistent Effects on Hippocampal Structure and Function.
Authors: Butler PM, Barash JA, Casaletto KB, Cotter DL, La Joie R, Geschwind MD, Rosen HJ, Kramer JH, Miller BL PMID: 31177905 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 12, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Treating Alcohol Use Disorder in U.S. Veterans: The Role of Traumatic Brain Injury.
CONCLUSIONS: Intensive outpatient programs are efficacious alternatives to treat AUD in veterans, although the role of pharmacological treatment is not completely elucidated. Glutamatergic agents appear to be less effective than opiate antagonists to prevent relapse to heavy drinking and to increase cumulative abstinence. Future studies should examine novel pharmacological and nonpharmacological options. PMID: 31117905 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - May 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Ages at Onset of Anxiety and Depressive Disorders in Parkinson's Disease.
Authors: Seritan AL, Rienas C, Duong T, Delucchi K, Ostrem JL Abstract OBJECTIVE: Parkinson's disease (PD) is a quintessential neuropsychiatric condition in which anxiety and depressive symptoms are common and may precede motor manifestations. The authors explored the ages at onset of anxiety and depressive disorders among patients with PD evaluated by psychiatrists at a deep brain stimulation center. METHODS: Psychiatric diagnoses and ages at onset were collected via clinical interviews. The ages at PD diagnosis were ascertained by chart review. Onset ages for anxiety and depressive disorders (overall and for ...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - May 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Hiding in Plain Sight: Functional Neurological Disorders in the News.
CONCLUSIONS: Functional neurological disorders are often wrongly considered a rare medical curiosity of the past. However, these findings suggest that, while they are largely absent from public discourse, they often appear in the news incognito, hiding in plain sight. PMID: 31117907 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - May 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Association of Working Memory With Distributed Executive Control Networks in Schizophrenia.
CONCLUSIONS: These results provide supporting evidence for the multicomponent model of working memory in terms of the biology underlying MCCB findings. PMID: 31117908 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - May 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

A Continuous Clustering Algorithm for Detection of Local Sleep in Humans.
CONCLUSIONS: This study reveals evidence of local sleep during the wake state in humans. PMID: 31046590 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - May 5, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Impaired Empathy Versus General Hypoemotionality in Frontotemporal Dementia.
CONCLUSIONS: These results indicate that patients with bvFTD have decreased empathic behavior with or without emotional blunting, and they exhibit decreased psychophysiological responses to empathy stimuli, independent of general emotion. These preliminary findings suggest a specific impairment in emotional empathy, possibly related to impairment of the emotional appraisal role of the dACC. PMID: 31046591 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - May 5, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Long-Standing Psychiatric Features as the Only Clinical Presentation of Vanishing White Matter Disease.
Authors: Accogli A, Brais B, Tampieri D, La Piana R PMID: 31046592 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - May 5, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Association of COMT Val158Met Polymorphism With Delirium Risk and Outcomes After Traumatic Brain Injury.
Authors: Nekrosius D, Kaminskaite M, Jokubka R, Pranckeviciene A, Lideikis K, Tamasauskas A, Bunevicius A Abstract OBJECTIVE: The authors investigated the association of the catechol-o-methyltransferase (COMT) gene Val158Met polymorphism with delirium risk and functional and cognitive outcomes among patients with complicated mild to moderate traumatic brain injury (TBI). METHODS: In a prospective observational cohort study, patients were monitored for occurrence of delirium during the first 4 days of admission by using the Confusion Assessment Method. Functional and cognitive outcomes were evaluated with the Gl...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - May 5, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Low-Frequency Right Repetitive Transcranial Magnetic Stimulation for the Treatment of Depression After Traumatic Brain Injury: A Randomized Sham-Controlled Pilot Study.
CONCLUSIONS: These findings suggest that the observed effects of LFR rTMS over the right DLPFC in TBI depression and co-occurring neuropsychiatric symptoms are small, at best, and, preliminarily, that low-frequency right DLPFC stimulation has limited potential in this patient population. However, studies employing different rTMS parameters (e.g., type, location, frequency, duration) or other participant characteristics (e.g., TBI severity, chronicity, comorbidity, concurrent treatment) may potentially yield different responses. PMID: 31018810 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and C...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 26, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Anger and Depression in Middle-Aged Men: Implications for a Clinical Diagnosis of Chronic Traumatic Encephalopathy.
Authors: Iverson GL, Terry DP, Luz M, Zafonte R, McCrory P, Solomon GS, Gardner AJ Abstract OBJECTIVE: In recent years, it has been proposed that problems with anger control and depression define clinical features of chronic traumatic encephalopathy (CTE). The authors examined anger problems and depression in middle-aged men from the general population and related those findings to the proposed clinical criteria for CTE. METHODS: A sample of 166 community-dwelling men ages 40-60 was extracted from the normative database of the National Institutes of Health Toolbox. All participants denied prior head injury or t...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 26, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Cognitive Impairment and Predicting Response to Treatment in an Intensive Clinical Program for Post-9/11 Veterans With Posttraumatic Stress Disorder.
This study examined whether objectively measured pretreatment cognitive impairment predicted worse response to treatment for posttraumatic stress disorder. Participants were 113 veterans and active duty service members who participated in a new multidisciplinary 2-week intensive clinical program that included individual trauma-focused cognitive-behavioral therapy, group psychotherapy, psychoeducation, skills-building groups, and complementary and alternative medicine treatments (mean age: 39.7 years [SD=8.5]; 20% women). METHODS: Prior to treatment, participants completed a brief computerized cognitive battery (CNS Vit...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 26, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Moral Injury and PTSD: Often Co-Occurring Yet Mechanistically Different.
Authors: Barnes HA, Hurley RA, Taber KH PMID: 31012825 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

The Last Witness to Creation: A Case of Charles Bonnet Syndrome.
Authors: Ramírez-Bermúdez J PMID: 31012826 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Chronic Traumatic Encephalopathy: A Clinical Perspective.
Authors: Filley CM, Arciniegas DB, Brenner LA, Anderson CA, Kelly JP PMID: 31012827 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Long-Term Neuropsychological and Psychiatric Outcomes in Susac's Syndrome.
Authors: Bolton C, Lacy M PMID: 31012828 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 25, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Individualized Connectome-Targeted Transcranial Magnetic Stimulation for Neuropsychiatric Sequelae of Repetitive Traumatic Brain Injury in a Retired NFL Player.
CONCLUSIONS:: These results highlight the possibility of individualized neuromodulation and biomarker-based monitoring for neuropsychiatric sequelae of repetitive TBI. PMID: 30945588 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 6, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Neuroprotective Benefits of Antidepressants in Multiple Sclerosis: Are We Missing the Mark?
Authors: Grech LB, Butler E, Stuckey S, Hester R Abstract The potential of antidepressant medication to have a neuroprotective effect for people with multiple sclerosis (MS) has received increased interest in recent years. The possibility of antidepressants, particularly fluoxetine, for potential repurposing to treat primary progressive and secondary progressive MS is of interest as a result of the relative lack of disease-modifying medications for these subtypes. A number of animal studies have found positive results for a neuroprotective effect of antidepressant use in MS, with human studies showing mixed results...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - April 6, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

An Investigation Into Response Inhibition in Distinct Clinical Groups Within Obsessive-Compulsive Disorder.
CONCLUSIONS:: On the basis of these results, it would seem unlikely that symptom clusters have contributed to previous inconsistencies in the literature. Comorbid depression, which may have affected previous results, should be considered in future research. PMID: 30888920 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - March 20, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Biomarkers of Autoimmunity in Acute Psychiatric Disorders.
CONCLUSIONS:: Autoimmune autoantibodies seem to be equally prevalent in patients with acute psychiatric conditions with and without psychotic and affective disorders. This result challenges the idea that these autoantibodies have specificity for certain psychiatric disorders. PMID: 30888921 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - March 20, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

SHANK3 Mutation and Mosaic Turner Syndrome in a Female Patient With Intellectual Disability and Psychiatric Features.
Authors: Accogli A, Yang R, Blain-Juste ME, Braverman N, Shah J, Trakadis Y PMID: 30888922 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - March 20, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Progressive Dementia Revealing an Atypical Encephalitis: Neuroimaging Aspects.
Authors: Makhtar Ba EH, Guerrier L, Benaiteau M, Rigal E, Mirabel H, Perez F, Salleles E, Martin-Blondel G, Pariente J PMID: 30848988 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - March 10, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Systematic Literature Review of Quetiapine for the Treatment of Psychosis in Patients With Parkinsonism.
CONCLUSIONS:: The efficacy of quetiapine in RCTs for psychosis in parkinsonism is no better than that for placebo or clozapine. On the basis of novel data, clinicians should reevaluate traditional viewpoints on the benefits of quetiapine for psychosis in parkinsonism. PMID: 30848989 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - March 10, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

The ALPIM (Anxiety, Laxity, Pain, Immune, and Mood) Syndrome in Adolescents and Young Adults: A Cohort Study.
Authors: Singh D, Rocio Martinez W, Anand N, Pinkhasov A, Calixte R, Bulbena A, Coplan JD Abstract OBJECTIVE:: ALPIM (anxiety, laxity, pain, immune, and mood) syndrome has been previously described in adults. The authors aimed to identify its occurrence in adolescents and confirm its existence in adults. Given the association of the disorder with somatic symptoms, separation anxiety disorder (SAD) was explored as an ALPIM comorbidity. METHODS:: Medical records of patients aged 11-34 with a diagnosis of depression or anxiety (panic disorder, SAD, social anxiety or generalized anxiety disorder) seen during a 1-ye...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - February 24, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Deep Brain Stimulation and Cognitive Outcomes Among Patients With Parkinson's Disease: A Historical Cohort Study.
CONCLUSIONS:: GPi may be a preferred target for DBS in patients with Parkinson's disease when considering cognitive outcomes. PMID: 30791806 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - February 24, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Neurodegenerative Dementias: Improving Brain Health to Decrease Risk.
Authors: Bateman JR, Hurley RA, Taber KH PMID: 30686211 [PubMed - in process] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - January 29, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Brain MR Radiomics to Differentiate Cognitive Disorders.
CONCLUSIONS:: MR radiomics may be a promising tool to classify various cognitive groups. PMID: 30636564 [PubMed - as supplied by publisher] (Source: Journal of Neuropsychiatry and Clinical Neurosciences)
Source: Journal of Neuropsychiatry and Clinical Neurosciences - January 15, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research