The Toxicology Investigators Consortium 2022 Annual Report
J Med Toxicol. 2023 Aug 29. doi: 10.1007/s13181-023-00962-2. Online ahead of print.ABSTRACTSince 2010, medical toxicology physicians from the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) have provided reports on their in-hospital and clinic patient consultations to a national case registry, known as the ToxIC Core Registry. De-identified patient data entered into the registry includes patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality. This thirteenth annual report pro...
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Alexandra M Amaducci Sharan L Campleman Shao Li Dana L Karshenas Meghan B Spyres Lynn A Farrugia A Min Kang Rachel E Culbreth Paul M Wax Jeffrey Brent Kim Aldy Toxicology Investigators Consortium Study Group Source Type: research

Assessing Platelet Mitochondrial Dysfunction in a Murine Model of Acute Acetaminophen Toxicity
CONCLUSIONS: Platelet oxygen consumption as a measure of mitochondrial function may be useful as a biomarker of hepatic APAP toxicity in the setting of moderate to severe overdose. Treatment with 4-MP decreases hepatic necrosis and may mitigate the harmful effects of APAP on platelet mitochondrial function detected via POC.PMID:37644341 | DOI:10.1007/s13181-023-00964-0 (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Carolyn Fox Michael L Ekaney Michael Runyon Hieu M Nguyen Philip J Turk Iain H McKillop Christine M Murphy Source Type: research

The Toxicology Investigators Consortium 2022 Annual Report
J Med Toxicol. 2023 Aug 29. doi: 10.1007/s13181-023-00962-2. Online ahead of print.ABSTRACTSince 2010, medical toxicology physicians from the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) have provided reports on their in-hospital and clinic patient consultations to a national case registry, known as the ToxIC Core Registry. De-identified patient data entered into the registry includes patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality. This thirteenth annual report pro...
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Alexandra M Amaducci Sharan L Campleman Shao Li Dana L Karshenas Meghan B Spyres Lynn A Farrugia A Min Kang Rachel E Culbreth Paul M Wax Jeffrey Brent Kim Aldy Toxicology Investigators Consortium Study Group Source Type: research

Assessing Platelet Mitochondrial Dysfunction in a Murine Model of Acute Acetaminophen Toxicity
CONCLUSIONS: Platelet oxygen consumption as a measure of mitochondrial function may be useful as a biomarker of hepatic APAP toxicity in the setting of moderate to severe overdose. Treatment with 4-MP decreases hepatic necrosis and may mitigate the harmful effects of APAP on platelet mitochondrial function detected via POC.PMID:37644341 | DOI:10.1007/s13181-023-00964-0 (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Carolyn Fox Michael L Ekaney Michael Runyon Hieu M Nguyen Philip J Turk Iain H McKillop Christine M Murphy Source Type: research

The Toxicology Investigators Consortium 2022 Annual Report
J Med Toxicol. 2023 Aug 29. doi: 10.1007/s13181-023-00962-2. Online ahead of print.ABSTRACTSince 2010, medical toxicology physicians from the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) have provided reports on their in-hospital and clinic patient consultations to a national case registry, known as the ToxIC Core Registry. De-identified patient data entered into the registry includes patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality. This thirteenth annual report pro...
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Alexandra M Amaducci Sharan L Campleman Shao Li Dana L Karshenas Meghan B Spyres Lynn A Farrugia A Min Kang Rachel E Culbreth Paul M Wax Jeffrey Brent Kim Aldy Toxicology Investigators Consortium Study Group Source Type: research

Assessing Platelet Mitochondrial Dysfunction in a Murine Model of Acute Acetaminophen Toxicity
CONCLUSIONS: Platelet oxygen consumption as a measure of mitochondrial function may be useful as a biomarker of hepatic APAP toxicity in the setting of moderate to severe overdose. Treatment with 4-MP decreases hepatic necrosis and may mitigate the harmful effects of APAP on platelet mitochondrial function detected via POC.PMID:37644341 | DOI:10.1007/s13181-023-00964-0 (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Carolyn Fox Michael L Ekaney Michael Runyon Hieu M Nguyen Philip J Turk Iain H McKillop Christine M Murphy Source Type: research

The Toxicology Investigators Consortium 2022 Annual Report
J Med Toxicol. 2023 Aug 29. doi: 10.1007/s13181-023-00962-2. Online ahead of print.ABSTRACTSince 2010, medical toxicology physicians from the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) have provided reports on their in-hospital and clinic patient consultations to a national case registry, known as the ToxIC Core Registry. De-identified patient data entered into the registry includes patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality. This thirteenth annual report pro...
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Alexandra M Amaducci Sharan L Campleman Shao Li Dana L Karshenas Meghan B Spyres Lynn A Farrugia A Min Kang Rachel E Culbreth Paul M Wax Jeffrey Brent Kim Aldy Toxicology Investigators Consortium Study Group Source Type: research

Assessing Platelet Mitochondrial Dysfunction in a Murine Model of Acute Acetaminophen Toxicity
CONCLUSIONS: Platelet oxygen consumption as a measure of mitochondrial function may be useful as a biomarker of hepatic APAP toxicity in the setting of moderate to severe overdose. Treatment with 4-MP decreases hepatic necrosis and may mitigate the harmful effects of APAP on platelet mitochondrial function detected via POC.PMID:37644341 | DOI:10.1007/s13181-023-00964-0 (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Carolyn Fox Michael L Ekaney Michael Runyon Hieu M Nguyen Philip J Turk Iain H McKillop Christine M Murphy Source Type: research

The Toxicology Investigators Consortium 2022 Annual Report
J Med Toxicol. 2023 Aug 29. doi: 10.1007/s13181-023-00962-2. Online ahead of print.ABSTRACTSince 2010, medical toxicology physicians from the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) have provided reports on their in-hospital and clinic patient consultations to a national case registry, known as the ToxIC Core Registry. De-identified patient data entered into the registry includes patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality. This thirteenth annual report pro...
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Alexandra M Amaducci Sharan L Campleman Shao Li Dana L Karshenas Meghan B Spyres Lynn A Farrugia A Min Kang Rachel E Culbreth Paul M Wax Jeffrey Brent Kim Aldy Toxicology Investigators Consortium Study Group Source Type: research

Assessing Platelet Mitochondrial Dysfunction in a Murine Model of Acute Acetaminophen Toxicity
CONCLUSIONS: Platelet oxygen consumption as a measure of mitochondrial function may be useful as a biomarker of hepatic APAP toxicity in the setting of moderate to severe overdose. Treatment with 4-MP decreases hepatic necrosis and may mitigate the harmful effects of APAP on platelet mitochondrial function detected via POC.PMID:37644341 | DOI:10.1007/s13181-023-00964-0 (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Carolyn Fox Michael L Ekaney Michael Runyon Hieu M Nguyen Philip J Turk Iain H McKillop Christine M Murphy Source Type: research

The Toxicology Investigators Consortium 2022 Annual Report
J Med Toxicol. 2023 Aug 29. doi: 10.1007/s13181-023-00962-2. Online ahead of print.ABSTRACTSince 2010, medical toxicology physicians from the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) have provided reports on their in-hospital and clinic patient consultations to a national case registry, known as the ToxIC Core Registry. De-identified patient data entered into the registry includes patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality. This thirteenth annual report pro...
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Alexandra M Amaducci Sharan L Campleman Shao Li Dana L Karshenas Meghan B Spyres Lynn A Farrugia A Min Kang Rachel E Culbreth Paul M Wax Jeffrey Brent Kim Aldy Toxicology Investigators Consortium Study Group Source Type: research

Assessing Platelet Mitochondrial Dysfunction in a Murine Model of Acute Acetaminophen Toxicity
CONCLUSIONS: Platelet oxygen consumption as a measure of mitochondrial function may be useful as a biomarker of hepatic APAP toxicity in the setting of moderate to severe overdose. Treatment with 4-MP decreases hepatic necrosis and may mitigate the harmful effects of APAP on platelet mitochondrial function detected via POC.PMID:37644341 | DOI:10.1007/s13181-023-00964-0 (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Carolyn Fox Michael L Ekaney Michael Runyon Hieu M Nguyen Philip J Turk Iain H McKillop Christine M Murphy Source Type: research

The Toxicology Investigators Consortium 2022 Annual Report
J Med Toxicol. 2023 Aug 29. doi: 10.1007/s13181-023-00962-2. Online ahead of print.ABSTRACTSince 2010, medical toxicology physicians from the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) have provided reports on their in-hospital and clinic patient consultations to a national case registry, known as the ToxIC Core Registry. De-identified patient data entered into the registry includes patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality. This thirteenth annual report pro...
Source: Journal of Medical Toxicology - August 29, 2023 Category: Toxicology Authors: Alexandra M Amaducci Sharan L Campleman Shao Li Dana L Karshenas Meghan B Spyres Lynn A Farrugia A Min Kang Rachel E Culbreth Paul M Wax Jeffrey Brent Kim Aldy Toxicology Investigators Consortium Study Group Source Type: research

Factors Affecting the Choice to Specialize in Medical Toxicology
CONCLUSIONS: Among current fellows and recent graduates of medical toxicology, having a mentor in the field of medical toxicology, having exposure to medical toxicology during residency, and participating in a clinical rotation in medical toxicology were common shared experiences that led to the decision to subspecialize in the field. These results may guide targeted intervention to continue to recruit strong candidates to medical toxicology.PMID:37639079 | DOI:10.1007/s13181-023-00965-z (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - August 28, 2023 Category: Toxicology Authors: Michael Keenan Nicholas Titelbaum Kyle Suen Brian Murray Paul Wax Emily Kiernan Source Type: research

Factors Affecting the Choice to Specialize in Medical Toxicology
CONCLUSIONS: Among current fellows and recent graduates of medical toxicology, having a mentor in the field of medical toxicology, having exposure to medical toxicology during residency, and participating in a clinical rotation in medical toxicology were common shared experiences that led to the decision to subspecialize in the field. These results may guide targeted intervention to continue to recruit strong candidates to medical toxicology.PMID:37639079 | DOI:10.1007/s13181-023-00965-z (Source: Journal of Medical Toxicology)
Source: Journal of Medical Toxicology - August 28, 2023 Category: Toxicology Authors: Michael Keenan Nicholas Titelbaum Kyle Suen Brian Murray Paul Wax Emily Kiernan Source Type: research