AICRF: ancestry inference of admixed population with deep conditional random field
In this study, we first present a heuristic function to determine a proper window length for LAI methods. This heuristic is based on the distance between the ancestral populations of admixed individuals. Then we introduce a method for ancestry inference of admixed population with deep conditional random field (AICRF). AICRF uses a conditional random field (CRF) parameterized by probable extreme learning machines (PELMs) trained on reference panels where PELM is a novel probabilistic ELM classifier. This method does not require many statistical or biological parameters. We evaluate the performance of AICRF in comparison wit...
Source: Journal of Genetics - October 18, 2023 Category: Genetics & Stem Cells Authors: Farhad Alizadeh Hamid Jazayeriy Omid Jazayeri Fatemeh Vafaee Source Type: research
The formate dehydrogenase enhances aluminum tolerance of tobacco
This study aims to ascertain GmFDH function in conferring tolerance to aluminum (Al) stress. The bioinformatics analysis demonstrates that GmFDH from Tamba black soybean (TBS) encodes FDH. Quantitative reverse transcription-PCR (qRT-PCR) showed that GmFDH expression was induced by Al stress with a concentration-time-specific pattern. Moreover, Al stress promotes formate content and activates FDH activity. Further studies revealed that GmFDH overexpression alleviated root growth of tobacco under Al stress inhibition and reduced Al and ROS accumulation in roots. In addition, transgenic tobacco had much more root citrate exud...
Source: Journal of Genetics - October 18, 2023 Category: Genetics & Stem Cells Authors: Yonghong Xie Yunmin Wei Rongrong Han Shitian Yu Hui Xu Caode Jiang Yongxiong Yu Source Type: research
Indigenous population genome databases for India and South Asia: emerging need for health and social applications
J Genet. 2023;102:46.ABSTRACTWith increased technological sophistication and rapidly reducing costs, currently, a huge amount of personal and populationlevel human genomic data and information is generated globally. There is an urgent need for an adequately curated and annotated human genome variant database for successful and large-scale application and translation in biomedical research, medical (healthcare) applications, socio-economic benefits and many other applications. The bulk of the available genomic data is generated from peoples of European descent. The genome data, particularly the human genome variant data is ...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Dhavendra Kumar Source Type: research
Serum exosomal hsa_circRNA_0001842 is the potential biomarker for diagnosing lower limb vascular disease in type 2 diabetes mellitus
In conclusion, hsa_circ_0001842 was found as a potential diagnostic biomarker for T2DM with LLVD.PMID:37798872 (Source: Journal of Genetics)
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Qian-Qian Liu Xing-Hui Liu Hai-Ming Wang Li-Min Xu Xiao-Jing Zhao Shu-Guang Han Zuo-Hua Lu Source Type: research
Mendel did not study common, naturally occurring phenotypes
J Genet. 2023;102:48.ABSTRACTModern genetics research increasingly reveals that what is commonly termed Mendelian genetics occurs rarely in nature, especially with regard to the effects that genetic variation exerts on human characteristics. It has been argued that an inappropriate emphasis on Mendel's work could distort the public understanding of genetics and indeed in the UK Mendel has been completely dropped from the official school syllabus. There is a widespread misunderstanding that Mendel studied common phenotypes such as height and colour in individual pea plants. In fact, he studied a handful of specially selecte...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: David Curtis Source Type: research
Indigenous population genome databases for India and South Asia: emerging need for health and social applications
J Genet. 2023;102:46.ABSTRACTWith increased technological sophistication and rapidly reducing costs, currently, a huge amount of personal and populationlevel human genomic data and information is generated globally. There is an urgent need for an adequately curated and annotated human genome variant database for successful and large-scale application and translation in biomedical research, medical (healthcare) applications, socio-economic benefits and many other applications. The bulk of the available genomic data is generated from peoples of European descent. The genome data, particularly the human genome variant data is ...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Dhavendra Kumar Source Type: research
Serum exosomal hsa_circRNA_0001842 is the potential biomarker for diagnosing lower limb vascular disease in type 2 diabetes mellitus
In conclusion, hsa_circ_0001842 was found as a potential diagnostic biomarker for T2DM with LLVD.PMID:37798872 (Source: Journal of Genetics)
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Qian-Qian Liu Xing-Hui Liu Hai-Ming Wang Li-Min Xu Xiao-Jing Zhao Shu-Guang Han Zuo-Hua Lu Source Type: research
Mendel did not study common, naturally occurring phenotypes
J Genet. 2023;102:48.ABSTRACTModern genetics research increasingly reveals that what is commonly termed Mendelian genetics occurs rarely in nature, especially with regard to the effects that genetic variation exerts on human characteristics. It has been argued that an inappropriate emphasis on Mendel's work could distort the public understanding of genetics and indeed in the UK Mendel has been completely dropped from the official school syllabus. There is a widespread misunderstanding that Mendel studied common phenotypes such as height and colour in individual pea plants. In fact, he studied a handful of specially selecte...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: David Curtis Source Type: research
Indigenous population genome databases for India and South Asia: emerging need for health and social applications
J Genet. 2023;102:46.ABSTRACTWith increased technological sophistication and rapidly reducing costs, currently, a huge amount of personal and populationlevel human genomic data and information is generated globally. There is an urgent need for an adequately curated and annotated human genome variant database for successful and large-scale application and translation in biomedical research, medical (healthcare) applications, socio-economic benefits and many other applications. The bulk of the available genomic data is generated from peoples of European descent. The genome data, particularly the human genome variant data is ...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Dhavendra Kumar Source Type: research
Serum exosomal hsa_circRNA_0001842 is the potential biomarker for diagnosing lower limb vascular disease in type 2 diabetes mellitus
In conclusion, hsa_circ_0001842 was found as a potential diagnostic biomarker for T2DM with LLVD.PMID:37798872 (Source: Journal of Genetics)
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Qian-Qian Liu Xing-Hui Liu Hai-Ming Wang Li-Min Xu Xiao-Jing Zhao Shu-Guang Han Zuo-Hua Lu Source Type: research
Mendel did not study common, naturally occurring phenotypes
J Genet. 2023;102:48.ABSTRACTModern genetics research increasingly reveals that what is commonly termed Mendelian genetics occurs rarely in nature, especially with regard to the effects that genetic variation exerts on human characteristics. It has been argued that an inappropriate emphasis on Mendel's work could distort the public understanding of genetics and indeed in the UK Mendel has been completely dropped from the official school syllabus. There is a widespread misunderstanding that Mendel studied common phenotypes such as height and colour in individual pea plants. In fact, he studied a handful of specially selecte...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: David Curtis Source Type: research
Indigenous population genome databases for India and South Asia: emerging need for health and social applications
J Genet. 2023;102:46.ABSTRACTWith increased technological sophistication and rapidly reducing costs, currently, a huge amount of personal and populationlevel human genomic data and information is generated globally. There is an urgent need for an adequately curated and annotated human genome variant database for successful and large-scale application and translation in biomedical research, medical (healthcare) applications, socio-economic benefits and many other applications. The bulk of the available genomic data is generated from peoples of European descent. The genome data, particularly the human genome variant data is ...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Dhavendra Kumar Source Type: research
Serum exosomal hsa_circRNA_0001842 is the potential biomarker for diagnosing lower limb vascular disease in type 2 diabetes mellitus
In conclusion, hsa_circ_0001842 was found as a potential diagnostic biomarker for T2DM with LLVD.PMID:37798872 (Source: Journal of Genetics)
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Qian-Qian Liu Xing-Hui Liu Hai-Ming Wang Li-Min Xu Xiao-Jing Zhao Shu-Guang Han Zuo-Hua Lu Source Type: research
Mendel did not study common, naturally occurring phenotypes
J Genet. 2023;102:48.ABSTRACTModern genetics research increasingly reveals that what is commonly termed Mendelian genetics occurs rarely in nature, especially with regard to the effects that genetic variation exerts on human characteristics. It has been argued that an inappropriate emphasis on Mendel's work could distort the public understanding of genetics and indeed in the UK Mendel has been completely dropped from the official school syllabus. There is a widespread misunderstanding that Mendel studied common phenotypes such as height and colour in individual pea plants. In fact, he studied a handful of specially selecte...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: David Curtis Source Type: research
Indigenous population genome databases for India and South Asia: emerging need for health and social applications
J Genet. 2023;102:46.ABSTRACTWith increased technological sophistication and rapidly reducing costs, currently, a huge amount of personal and populationlevel human genomic data and information is generated globally. There is an urgent need for an adequately curated and annotated human genome variant database for successful and large-scale application and translation in biomedical research, medical (healthcare) applications, socio-economic benefits and many other applications. The bulk of the available genomic data is generated from peoples of European descent. The genome data, particularly the human genome variant data is ...
Source: Journal of Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Dhavendra Kumar Source Type: research
