Tru-cut/core biopsy versus FNAC: Pulmonary tumors
Deepali JainJournal of Cytology 2018 35(3):183-186
Primary lung epithelial malignancies are the most common neoplasms among all pulmonary tumors. Lung cancer (LC) is the leading cause of cancer-related mortality for which a histologic or cytologic confirmation of malignancy is required before treatment. Specimen management is an important task for pathologists in the field of LC. Biopsy and fine needle aspiration are comparable. It is desirable to have both for diagnosis and mutation testing to maximize their use for patient care. (Source: Journal of Cytology)
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Deepali Jain Source Type: research
Trucut biopsy vs FNAC of pelvic tumors-who wins the match ?
Asaranti Kar, Bharat Satapathy, Kaumudee Pattnaik, Prafulla K DashJournal of Cytology 2018 35(3):179-182
Preoperative pathologic diagnosis of pelvic tumors is mandatory for proper management of patients like neoadjuvant chemotherapy and interval debulking. Currently there are many minimally invasive methods available which include fine-needle aspiration cytology (FNAC) and trucut biopsy, mostly complimentary to each other. FNAC is a cheap, rapid and sensitive method for diagnosis of pelvic tumors. It can be done as an outpatient procedure without complications. But with it, the tissue architecture cannot be seen. Trucut b...
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Asaranti Kar Bharat Satapathy Kaumudee Pattnaik Prafulla K Dash Source Type: research
FNAC Versus CNB: Who wins the match in breast lesions ?
Indranil ChakrabartiJournal of Cytology 2018 35(3):176-178
The triple test lies at the heart of preoperative diagnosis of breast lesions. Raised awareness and self-assessment have significantly increased the rate of detection of breast pathologies. The managing clinicians usually decide the imaging and pathological modalities to the best interest of the patients. Core needle biopsy (CNB), cell-block studies, and fine needle aspiration cytology (FNAC) coupled with rapid on-site evaluation (ROSE) have significantly increased the accuracy of preoperative diagnosis. Immunocytochemistry, immunohistochemistry on cell blocks, an...
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Indranil Chakrabarti Source Type: research
Trucut/Core biopsy versus FNAC: Who wins the match ? thyroid lesions and salivary gland lesions: An overview
We describe role of FNAC and CNB in thyroid and salivary gland lesions with detailed discussion of advantages and disadvantages of both these techniques. (Source: Journal of Cytology)
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Nalini Gupta Parikshaa Gupta Arvind Rajwanshi Source Type: research
Where to look for AFB in FNA Smears from tuberculous lymph nodes
Dev PrasoonJournal of Cytology 2018 35(3):170-172
Demonstration of acid fast bacilli (AFB) is essential for the definitive cytodiagnosis of tuberculosis. However, it is not seen in all cases of tuberculosis, being more commonly observed in necrotic lesions. Tuberculosis shows a spectrum of lesions that form a continuum extending from good immunity end with purely granulomatous lesions to poor immunity end with purely necrotic lesions. Each stage has distinctive microscopic picture and determines the chance of finding AFB. AFB yield was the highest (92.7%) in necrotic lesions containing eosinophilic structures (...
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Dev Prasoon Source Type: research
Contribution of immunocytochemistry to the diagnosis of usual and unusual lymphoma cases
Dilip K DasJournal of Cytology 2018 35(3):163-169
Some of the limitations of fine needle aspiration (FNA) in the cytodiagnosis of lymphoma include problems encountered in differentiating reactive hyperplasia from low-grade non-Hodgkin lymphoma (NHL), lower cytodiagnostic accuracy for NHL with a follicular (nodular) pattern and nodular sclerosis type of classical Hodgkin lymphoma (HL), and overlapping morphological features between T-cell-rich B-cell lymphoma (TCRBCL), anaplastic large cell lymphoma (ALCL), and HL. Immunocytochemistry may be of help in such situations. The B-cell lymphomas such as small lymphocytic lymphom...
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Dilip K Das Source Type: research
Can fine needle aspiration cytology be used as a & #8220;Proxy Gold Standard & #8221; to Diagnose tuberculous mastitis ?
Conclusion: In situations where prevalence of tuberculosis is high and where facilities for histopathological evaluation do not exist, FNAC can offer an optional alternative to base the therapeutic decision for starting antitubercular treatment. (Source: Journal of Cytology)
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Meherbano M Kamal Hemant R Kulkarni Manjiri M Makde Radha Munje Source Type: research
Role of p16/Ki-67 Dual immunostaining in detection of cervical cancer precursors
Conclusion: This dual immunostaining may potentially be a useful tool in the triage of the ASC-US and the LSIL group, considering the high sensitivity and specificity values. (Source: Journal of Cytology)
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Diya Das Moumita Sengupta Keya Basu Mona Tirkey Chhanda Datta Uttara Chatterjee Source Type: research
Correlative study of cytological features in grading of invasive breast carcinoma
Conclusions: Robinson's cytologic grading system is a reliable grading method on FNAC smears of cases of carcinoma breast. It correlates well with Elston–Ellis modification of Scarff–Bloom–Richardson grade in invasive ductal carcinoma of breast. (Source: Journal of Cytology)
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Anamika Sinha Satyajit S Gill Source Type: research
Cervicouterine cancer screening & #8211; TruScreen & #8482; vs. conventional cytology: Pilot study
Conclusions: TruScreen™ demonstrated low sensitivity and high specificity compared with conventional cytology, which had a high NPV. (Source: Journal of Cytology)
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: JE Salazar-Campos A Gonz & #225;lez-Enciso R D & #237;az-Molina ME Lara-Hern & #225;ndez J Coronel-Mart & #237;nez C P & #233;rez-Plasencia D Cant & #250; de Le & #243;n Source Type: research
Role of squash cytology in intraoperative diagnosis of spinal lesions
Conclusion: Inspite of having pitfalls and various limitations in case of spinal lesions, squash preparation is a rapid and easy method with fairly high diagnostic accuracy. So it can be reliably used as an intraoperative diagnostic tool in spinal lesions. (Source: Journal of Cytology)
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Mousumi Kar Moumita Sengupta Saurav Sarkar Saikat Bera Chhanda Datta Uttara Chatterjee Samarendra Nath Ghosh Source Type: research
Functional state of cells during their life and on their journey toward inactivity and death: Search for morphological evidence in thyroid fine needle aspiration smears
Dilip K DasJournal of Cytology 2018 35(3):131-138
Synthesis and storage of thyroglobulin as well as synthesis of thyroid hormones and their release into the circulation are important functions of thyroid, which were studied in fine needle aspiration (FNA) smears from thyroid lesions. Evidence of thyroglobulin synthesis was demonstrated in neoplastic and nonneoplastic follicular cells, especially in Hürthle cells, in the form of colloid inclusions. Whereas the pinocytic vesicles containing colloid at the luminal end of in nonneoplastic and neoplastic follicular cells indicated engulfment of colloid for synthesi...
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Dilip K Das Source Type: research
Cytological findings of a rare case of transitional cell carcinoma bladder presenting with supraclavicular lymphnode metastasis
Sana Ahuja, Nadeem Tanveer, Thaihamdao Haflongbar, Vinod K AroraJournal of Cytology 2018 35(2):129-130 (Source: Journal of Cytology)
Source: Journal of Cytology - March 22, 2018 Category: Cytology Authors: Sana Ahuja Nadeem Tanveer Thaihamdao Haflongbar Vinod K Arora Source Type: research
Cytological diagnosis of mazabraud & #39;s syndrome
Faheema Hasan, Vishal Dhingra, Anshul Singh, Vatsala MisraJournal of Cytology 2018 35(2):128-129 (Source: Journal of Cytology)
Source: Journal of Cytology - March 22, 2018 Category: Cytology Authors: Faheema Hasan Vishal Dhingra Anshul Singh Vatsala Misra Source Type: research
Papillary carcinoma thyroid presenting as huge scalp metastases
Adarsh Barwad, Prashant P Ramteke, Shivanand GamanagattiJournal of Cytology 2018 35(2):126-127 (Source: Journal of Cytology)
Source: Journal of Cytology - March 22, 2018 Category: Cytology Authors: Adarsh Barwad Prashant P Ramteke Shivanand Gamanagatti Source Type: research
