Diagnostic value of S100P, IMP3, Maspin, and pVHL in the differantial diagnosis of pancreatic ductal adenocarcinoma and normal/chronic pancreatitis in fine needle aspiration biopsy
Conclusion: We observed that dual response in triple test (positive staining with two of these three markers) of maspin, IMP3, and S100P immunocytochemistry is very sensitive and specific in differential diagnosis of PDA and non-neoplastic pancreatic lesions. pVHL may have an additional role, when triple assessment is not satisfactory. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Aysegul Aksoy-Altinboga Tolga Baglan Haldun Umudum Koray Ceyhan Source Type: research
Use of sialic acid as a complementary method in the cytological diagnosis: Preliminary study
Conclusion: It was observed that the change in sialic acid conformation detected through Sambucus nigra Lectin could be used as a complementary method for the diagnosis of malignancy in different cytological samples. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Adriana E Rocher Anabela A. G. Angeleri Fernando Guerra Luis A Palaoro Source Type: research
Utility of FNAC in dermatological manifestations of metastatic cancer with the review of the literature
Conclusion: FNAC is a minimally invasive method, which aides in prompt detection and appropriate management of cases presenting with skin nodules and clinically unsuspected of malignancy. Whereas in known primary tumor, it indicates dismal prognosis by diagnosing CM; in cases with unknown primaries, cytomorphology in conjunction with clinicoradiological findings often gives a clue to the possible primary site. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Barkha Gupta Varuna Mallya Shyama Jain PN Agarwal Source Type: research
Micronuclei as a predictor for oral carcinogenesis
Conclusion: MN assays can help in early detection of premalignant and malignant lesions, thereby improving survival and reducing morbidity associated with treatment. MN index is thus a feasible and economical method for screening high-risk populations of oral cancer, to be able to timely identify genomic damage in order to prevent the cancer epidemic. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Kamini Kiran Padmanidhi Agarwal Shailesh Kumar Kanav Jain Source Type: research
Role of rapid on-site evaluation in CT-guided fine needle aspiration cytology of lung nodules
Conclusion: CT-guided FNA with ROSE is a safe and useful tool in the diagnostic work-up of lung cancer patients. A multidisciplinary approach along with onsite evaluation of adequacy will increase the diagnostic utility of cytology in lung lesions. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: KR Anila Nileena Nayak M Venugopal K Jayasree Source Type: research
Evaluation of estrogen and progesterone receptors and Her-2 expression with grading in the fine-needle aspirates of patients with breast carcinoma
Conclusions: Fairly reliable results on grading and hormonal/Her-2neu status are possible when ICC is performed on qualitatively superior FNA material. This is particularly useful in the management of patients in certain settings like inoperable cases. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Pampa Ch Toi Siddaraju Neelaiah Kadambari Dharanipragada Kumar Surendra Source Type: research
Cytological scoring of breast lesions and comparison with histopathological findings
Conclusion: The scoring system is easily reproducible, simple, and reliable. MMSI proved good histopathological correlation in category I and IV. This scoring technique has clearly demarcated those cases requiring surgical management. It is applicable for palpable and nonpalpable cases. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Betty Abraham TR Sarojini Source Type: research
Cytopathology of pulmonary lesions: A tertiary care center experience
Conclusion: Lung carcinoma is presently the leading cause of cancer deaths while TB is still a common cause of death in developing countries. Cytopathology has a definite role in diagnosis of malignant lesions and also contributes in diagnosis of unsuspected chronic infections. Cytological diagnosis is fairly accurate if the specimen obtained is adequate and representative. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Supriya Ghildiyal Seema Acharya Brijesh Thakur Jagdish Rawat Rajnish Kumar Source Type: research
Cytomorphological differences between liquid-based cytology and conventional smears in fine-needle aspirates of thyroid lesions
Conclusion: LBC can supplement CS but cannot replace it. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Shuchita Sharma Shilpi Agarwal Manjula Jain Gautam Bir Singh Manoj Andley Source Type: research
Cyto-histopathological correlation of skin adnexal tumors: A short series
Conclusion: FNAC is a simple, safe, and cost-effective tool in diagnosing skin ATs. Cytological diagnosis of these lesions is depends on clinical correlation and cytomorphological features. FNAC in lesions suspected to be malignant can guide the surgeon regarding extent of excision. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Amita Arora Annu Nanda Sangeeta Lamba Source Type: research
Rehydration of air-dried smears with normal saline: An alternative for conventional wet fixation method in cervical cytological study
Conclusion: Rehydrated air-dried technique can be satisfactory alternative for conventional wet fixation method which can be followed routinely or in conjugation with C-PAPS, especially in cervical screening programs. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Sachin Shivaji Kapse Surekha U Arakeri Divya P Yerranguntla Source Type: research
Cytomorphological study of medullary carcinoma of breast in comparison to infiltrating ductal carcinoma
Conclusion: Though few variants of breast carcinoma contain lymphoplasmacytic infiltrate, the intensity and pattern of distribution of these lymphocytes and plasma cells in relation to tumor cells helps in distinguishing MBC from other breast carcinomas commonly IDC NOS on cytology. Also MBCs have a better prognosis when compared to IDC NOS. (Source: Journal of Cytology)
Source: Journal of Cytology - October 19, 2018 Category: Cytology Authors: Sajjan M Netra BR Vani V Srinivasa Murthy Source Type: research
Cytological diagnosis of an uncommon tumor of the minor salivary gland & #8211; Basal cell adenoma
Premila Desousa Rocha, RG Wiseman Pinto, Rajika Bhat, Durva Prabhugaonkar, Adora FernandesJournal of Cytology 2018 35(3):193-194 (Source: Journal of Cytology)
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Premila Desousa Rocha RG Wiseman Pinto Rajika Bhat Durva Prabhugaonkar Adora Fernandes Source Type: research
Cytodiagnosis of coexistence of leukemic infiltration and extramedullary hematopoiesis in a cervical lymph node, in T cell leukemia patient
Akanksha Bothale, Kalpana Bothale, Sadhana Mahore, Trupti DongreJournal of Cytology 2018 35(3):189-192
Extramedullary hematopoiesis (EMH) is a compensatory mechanism that occurs when the marrow is unable to maintain sufficient red cell mass. EMH generally occurs in the patients with deficient bone marrow hematopoiesis secondary to either peripheral red cell destruction or marrow replacement. Although EMH is known to occur in agnogenic myeloid metaplasia with myelofibrosis, chronic myelogenous leukemia, thalassemia, and infiltrative disorders, such as lymphomas, it is rare in acute leukemias. EMH is most commonly seen in t...
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Akanksha Bothale Kalpana Bothale Sadhana Mahore Trupti Dongre Source Type: research
Cytodiagnosis of primary thyroid lymphoma coincident with unnoticed papillary thyroid carcinoma: A case report and review of the literature
Gozde Kir, Billur Cosan Sarbay, Adnan OzpekJournal of Cytology 2018 35(3):187-189
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer, whereas primary thyroid lymphoma is very rare. Here, we report a case in which a right-sided nodule measuring 4.3 × 2.2 cm was examined using fine-needle aspiration biopsy. This revealed abundant monomorphic non-cohesive large lymphoid cells without thyroid follicular cells, on which basis acytodiagnosis of lymphoma coincident with lymphocytic thyroiditis was made. Subsequent histologic examination revealed CD45−, CD20+, and Bcl-6...
Source: Journal of Cytology - July 12, 2018 Category: Cytology Authors: Gozde Kir Billur Cosan Sarbay Adnan Ozpek Source Type: research
