Relationship between hydrogel spacer distribution and dosimetric parameters in linear-accelerator-based stereotactic body radiotherapy for prostate cancer
CONCLUSIONS: The SCR seems promising to predict the separation of the rectum from the PTV in linear-accelerator-based SBRT for prostate cancer.PMID:38319652 | DOI:10.1002/acm2.14294 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - February 6, 2024 Category: Physics Authors: Shingo Ohira Hideomi Yamashita Masanari Minamitani Subaru Sawayanagi Mami Ogita Toshikazu Imae Atsuto Katano Yuki Nozawa Takeshi Ohta Kanabu Nawa Teiji Nishio Masahiko Koizumi Keiichi Nakagawa Source Type: research

Commissioning and initial validation of Eclipse eMC algorithm for the electron FLASH research extension (FLEX) system for pre-clinical studies
CONCLUSIONS: The FLEX system was successfully commissioned in the commercial TPS using the eMC algorithm, which accurately modeled the forward-peaked nature of the FLASH beam. A commissioned TPS for FLASH will be useful for pre-clinical cell and animal studies, as well as in silico FLASH treatment planning studies for future clinical implementation.PMID:38319666 | DOI:10.1002/acm2.14289 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - February 6, 2024 Category: Physics Authors: Kyuhak Oh Kyle J Gallagher Ying Yan Sumin Zhou Source Type: research

Analysis of respiratory-induced motion trajectories of individual liver segments in patients with hepatocellular carcinoma
CONCLUSION: A significant amount of respiratory motion was detected in the CC direction, especially in S7, and S8. Despite the small effect of hysteresis, it can be observed specifically in the right lobe. Therefore, caution is required when using 4DCT to determine IM using only end-inspiration and end-expiration. Understanding the respiratory motion in individual liver segments can be helpful when selecting an appropriate treatment protocol.PMID:38303539 | DOI:10.1002/acm2.14257 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - February 2, 2024 Category: Physics Authors: Takahiro Kato Kimihiro Takemasa Tomohiro Ikeda Hisanori Sakagami Ryohei Kato Yuki Narita Sho Oyama Shinya Komori Hisashi Yamaguchi Masao Murakami Source Type: research

Resolving signal drift in the wall-mounted camera of the RGSC system
CONCLUSION: This proposed solution aims to minimize the systematic error in radiation delivery for patients undergoing motion management with wall-mounted camera RGSC systems, especially in conjunction with a bariatric CT couchtop.PMID:38306504 | DOI:10.1002/acm2.14291 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - February 2, 2024 Category: Physics Authors: Jeonghoon Park Justin D Gagneur Suzanne J Chungbin Yi Rong Seng Boh Lim Maria F Chan Source Type: research

Automated size-specific dose estimates framework in thoracic CT using convolutional neural network based on U-Net model
CONCLUSION: The proposed automated framework using a CNN offers a reliable and efficient solution for determining the Deff corr SSDE in thoracic CT.PMID:38295146 | DOI:10.1002/acm2.14283 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 31, 2024 Category: Physics Authors: Sakultala Ruenjit Punnarai Siricharoen Kitiwat Khamwan Source Type: research

Using standardized workflows and quantitative data-driven management to reduce time interval from simulation to treatment initiation
CONCLUSION: Establishing a standardized workflow and frequently measuring TTI resulted in shortening the TTI during the early years (in PI) and maintaining the established TTI in the subsequent years (in PII).PMID:38295191 | DOI:10.1002/acm2.14284 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 31, 2024 Category: Physics Authors: Naichang Yu Danielle LaHurd Anthony Mastroianni Anthony Magnelli Rahul Tendulkar Samuel T Chao John H Suh Ping Xia Source Type: research

Independent Monte Carlo dose calculation identifies single isocenter multi-target radiosurgery targets most likely to fail pre-treatment measurement
CONCLUSIONS: Independent MC complements pre-treatment QA measurement for SIMT SRS by identifying problematic individual targets prior to pre-treatment measurement, thus enabling plan modifications earlier in the planning process and guiding selection of targets for pre-treatment QA measurement.PMID:38289874 | DOI:10.1002/acm2.14290 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 30, 2024 Category: Physics Authors: Brett Erickson Yunfeng Cui Markus Alber Chunhao Wang Fang Fang Yin John Kirkpatrick Justus Adamson Source Type: research

Single isocenter versus dual isocenter treatment using flattening filter-free and jaw-tracking volumetrically modulated arc therapy for boot-shaped lung cancer: Evaluation of dosimetric and feasibility
CONCLUSIONS: Taking into account the dosimetric results and published clinical data on radiation-induced pulmonary injury, dual-isocenter jaw-tracking VMAT may be the optimal choice for treating boot-shaped lung cancer.PMID:38286001 | DOI:10.1002/acm2.14292 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 29, 2024 Category: Physics Authors: Lei Zhang Hang Cheng Fenglei Du Kainan Shao Shiming Zheng Yiwei Yang Guoping Shan Source Type: research

Intraoperative radiation therapy with 50  kV x-rays: A multi-institutional review
This report covers clinical implementation of a low kV intraoperative radiation therapy (IORT) program with the INTRABEAM® System (Carl Zeiss Meditec AG, Jena, Germany). Based on collective user experience from eight institutions, we discuss best methods of INTRABEAM quality assurance (QA) tests, commissioning measurements, clinical workflow, treatment planning, and potential avenues for research. The guide provides pertinent background information and clinical justification for IORT. It describes the INTRABEAM system and commissioning measurements along with a TG100 risk management analysis to ensure safety and accuracy ...
Source: Journal of Applied Clinical Medical Physics - January 27, 2024 Category: Physics Authors: Anil Sethi Sebastien Gros Patrik Brodin Beth Ghavidel Xuedong Chai Marija Popovic Wolfgang Axel Tom é Samuel Trichter Xiaofeng Yang Hualin Zhang Valery Uhl Source Type: research

Setup margins based on the inter- and intrafractional setup error of left-sided breast cancer radiotherapy using deep inspiration breath-hold technique (DIBH) and surface guided radiotherapy (SGRT)
CONCLUSION: With SGRT, excellent intrafractional and acceptable interfractional patient setup accuracy can be achieved for the radiotherapy of left-sided breast cancer using DIBH and modern radiation techniques. This allows for reducing the frequency of kV-CBCTs, thereby saving treatment time and radiation exposure.PMID:38273673 | DOI:10.1002/acm2.14271 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 26, 2024 Category: Physics Authors: Volker Rudat Yanyan Shi Ruping Zhao Wei Yu Source Type: research

Stereotactic radiotherapy of intracranial tumor beds on a ring-mounted Halcyon LINAC
CONCLUSIONS: When benchmarked against clinically delivered HyperArc treatments, the Halcyon brain SRT plans provided similar plan quality and delivery accuracy but achieved faster overall treatment times. We have started treating select brain SRT patients on the Halcyon RDS for patients having tumor beds greater than 1 cm in diameter with the closest OAR distance of greater than 2 cm away from the target. We recommend other clinics to consider commissioning SRT treatments on their Halcyon systems-allowing including remote Halcyon-only clinics to provide exceptionally high-quality therapeutic brain SRT treatments to an othe...
Source: Journal of Applied Clinical Medical Physics - January 26, 2024 Category: Physics Authors: Joshua Misa Shane McCarthy William St Clair Damodar Pokhrel Source Type: research

Verification of surface-guided radiation therapy (SGRT) alignment for proton breast and chest wall patients by comparison to CT-on-rails and kV-2D alignment
CONCLUSIONS: Due to the overall agreement between SGRT and IGRT within reasonable tolerance, SGRT has the potential to serve as a valuable auxiliary IGRT tool for proton breast treatment and may improve the efficiency of proton breast treatment.PMID:38268200 | PMC:PMC10860439 | DOI:10.1002/acm2.14263 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 25, 2024 Category: Physics Authors: Hui Zhao Vikren Sarkar Sara St James Adam Paxton Fan-Chi Frances Su Ryan G Price Christian Dial Matthew Poppe David Gaffney Bill Salter Source Type: research

A quantitative evaluation of the deep learning model of segmentation and measurement of cervical spine MRI in healthy adults
CONCLUSION: A deep learning model based on 3D U-Net automatically segmented and performed measurements on cervical spine MR images from healthy adults, paving the way for quantitative diagnosis models for spinal cord diseases.PMID:38269650 | DOI:10.1002/acm2.14282 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 25, 2024 Category: Physics Authors: Yifeng Zhu Yushi Li Kexin Wang Jinpeng Li Xiaodong Zhang Yaofeng Zhang Jialun Li Xiaoying Wang Source Type: research

A deep learning approach to remove contrast from contrast-enhanced CT for proton dose calculation
CONCLUSIONS: A deep learning approach was developed to generate NCECTs from CECTs. This approach could be useful for the proton dose calculation to reduce uncertainties caused by tissue motion between CECT and NCECT.PMID:38269961 | PMC:PMC10860532 | DOI:10.1002/acm2.14266 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 25, 2024 Category: Physics Authors: Xu Wang Yao Hao Ye Duan Deshan Yang Source Type: research

Gross failure rates and failure modes for a commercial AI-based auto-segmentation algorithm in head and neck cancer patients
CONCLUSION: True failures of the AI-based system were predominantly associated with a non-standard element within the CT scan. It is likely that these non-standard elements were the reason for the gross failure, and suggests that patient datasets used to train the AI model did not contain sufficient heterogeneity of data. Regardless of the reasons for failure, the true failure rate for the AI-based system in the H&N region for the OARs investigated was low (∼1%).PMID:38263866 | DOI:10.1002/acm2.14273 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - January 24, 2024 Category: Physics Authors: Simon W P Temple Carl G Rowbottom Source Type: research