International Journal of Medical Microbiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades
In this study, we present data corroborating our previous data demonstrating that basal clade B.12 can be divided into clades B.71 and B.72. By applying phylogenetic whole genome analysis as well as proteome analysis, we could verify that strains of these two clades are distinct from one another. This was confirmed by measuring the intensity of backscatter light on bacteria grown in liquid media. Strains belonging to clades B.6, B.71 or B.72 showed clade-specific backscatter growth curves. Furthermore, we present the whole genome sequence of strain A-1341, as a reference genome of clade B.71, and whole proteomes comparison...
Source: International Journal of Medical Microbiology - June 18, 2023 Category: Microbiology Authors: Kristin K öppen Kerstin Rydzewski Joerg Doellinger Kerstin Myrtenn äs Mats Forsman Sandra Appelt Holger Scholz Klaus Heuner Source Type: research

Heat shock protein 70 is involved in polaprezinc driven cell protection against Helicobacter pylori-induced injury
The objective of this study was to determine the protective effects of PZ on human gastric epithelial cells (GES-1) against H. pylori-induced damage, while also examining heat shock protein 70 (HSP70) as a potential underlying factor in this protection. Our findings revealed that PZ exerted bactericidal effects against H. pylori strains. We also observed that PZ mitigated the H. pylori-induced damage to GES-1 cells by increasing cell viability, reducing LDH release, and decreasing the secretion of pro-inflammatory factors such as MCP-1 and IL-6. Co-culturing PZ with GES-1 cells significantly up-regulated the GES-1 HSP70 ex...
Source: International Journal of Medical Microbiology - June 7, 2023 Category: Microbiology Authors: Fansen Meng Siying Zhu Meiliang Gong Hongjin Tao Weihua Wang Gangshi Wang Source Type: research

Heat shock protein 70 is involved in polaprezinc driven cell protection against Helicobacter pylori-induced injury
The objective of this study was to determine the protective effects of PZ on human gastric epithelial cells (GES-1) against H. pylori-induced damage, while also examining heat shock protein 70 (HSP70) as a potential underlying factor in this protection. Our findings revealed that PZ exerted bactericidal effects against H. pylori strains. We also observed that PZ mitigated the H. pylori-induced damage to GES-1 cells by increasing cell viability, reducing LDH release, and decreasing the secretion of pro-inflammatory factors such as MCP-1 and IL-6. Co-culturing PZ with GES-1 cells significantly up-regulated the GES-1 HSP70 ex...
Source: International Journal of Medical Microbiology - June 7, 2023 Category: Microbiology Authors: Fansen Meng Siying Zhu Meiliang Gong Hongjin Tao Weihua Wang Gangshi Wang Source Type: research

Heat shock protein 70 is involved in polaprezinc driven cell protection against Helicobacter pylori-induced injury
The objective of this study was to determine the protective effects of PZ on human gastric epithelial cells (GES-1) against H. pylori-induced damage, while also examining heat shock protein 70 (HSP70) as a potential underlying factor in this protection. Our findings revealed that PZ exerted bactericidal effects against H. pylori strains. We also observed that PZ mitigated the H. pylori-induced damage to GES-1 cells by increasing cell viability, reducing LDH release, and decreasing the secretion of pro-inflammatory factors such as MCP-1 and IL-6. Co-culturing PZ with GES-1 cells significantly up-regulated the GES-1 HSP70 ex...
Source: International Journal of Medical Microbiology - June 7, 2023 Category: Microbiology Authors: Fansen Meng Siying Zhu Meiliang Gong Hongjin Tao Weihua Wang Gangshi Wang Source Type: research

Heat shock protein 70 is involved in polaprezinc driven cell protection against Helicobacter pylori-induced injury
The objective of this study was to determine the protective effects of PZ on human gastric epithelial cells (GES-1) against H. pylori-induced damage, while also examining heat shock protein 70 (HSP70) as a potential underlying factor in this protection. Our findings revealed that PZ exerted bactericidal effects against H. pylori strains. We also observed that PZ mitigated the H. pylori-induced damage to GES-1 cells by increasing cell viability, reducing LDH release, and decreasing the secretion of pro-inflammatory factors such as MCP-1 and IL-6. Co-culturing PZ with GES-1 cells significantly up-regulated the GES-1 HSP70 ex...
Source: International Journal of Medical Microbiology - June 7, 2023 Category: Microbiology Authors: Fansen Meng Siying Zhu Meiliang Gong Hongjin Tao Weihua Wang Gangshi Wang Source Type: research

Heat shock protein 70 is involved in polaprezinc driven cell protection against Helicobacter pylori-induced injury
The objective of this study was to determine the protective effects of PZ on human gastric epithelial cells (GES-1) against H. pylori-induced damage, while also examining heat shock protein 70 (HSP70) as a potential underlying factor in this protection. Our findings revealed that PZ exerted bactericidal effects against H. pylori strains. We also observed that PZ mitigated the H. pylori-induced damage to GES-1 cells by increasing cell viability, reducing LDH release, and decreasing the secretion of pro-inflammatory factors such as MCP-1 and IL-6. Co-culturing PZ with GES-1 cells significantly up-regulated the GES-1 HSP70 ex...
Source: International Journal of Medical Microbiology - June 7, 2023 Category: Microbiology Authors: Fansen Meng Siying Zhu Meiliang Gong Hongjin Tao Weihua Wang Gangshi Wang Source Type: research