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Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Association between hospital onset of infection and outcomes in sepsis patients - A propensity score matched cohort study based on health claims data in Germany
CONCLUSIONS: HAI sepsis patients face an increased risk of adverse outcomes both during the acute sepsis episode and in the long-term. Measures to prevent HAI and its progression into sepsis may be an opportunity to mitigate the burden of long-term impairments and costs of sepsis, e.g., by early detection of HAI progressing into sepsis, particularly in normal wards; adequate sepsis management and adherence to sepsis bundles in hospital-acquired sepsis; and an improved infection prevention and control.PMID:38070459 | DOI:10.1016/j.ijmm.2023.151593 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - December 9, 2023 Category: Microbiology Authors: Norman Rose Melissa Spoden Antje Freytag Mathias Pletz Tim Eckmanns Lisa Wedekind Josephine Storch Peter Schlattmann Christiane S Hartog Konrad Reinhart Christian G ünster Carolin Fleischmann-Struzek Source Type: research

Interdisciplinary studies on Coxiella burnetii: From molecular to cellular, to host, to one health research
Int J Med Microbiol. 2023 Nov 29;313(6):151590. doi: 10.1016/j.ijmm.2023.151590. Online ahead of print.ABSTRACTThe Q-GAPS (Q fever GermAn interdisciplinary Program for reSearch) consortium was launched in 2017 as a German consortium of more than 20 scientists with exceptional expertise, competence, and substantial knowledge in the field of the Q fever pathogen Coxiella (C.) burnetii. C. burnetii exemplifies as a zoonotic pathogen the challenges of zoonotic disease control and prophylaxis in human, animal, and environmental settings in a One Health approach. An interdisciplinary approach to studying the pathogen is essentia...
Source: International Journal of Medical Microbiology - December 6, 2023 Category: Microbiology Authors: Benjamin U Bauer Michael R Knittler Jennifer Andrack Christian Berens Amely Campe Bahne Christiansen Akinyemi M Fasemore Silke F Fischer Martin Ganter Sophia K örner Gustavo R Makert Svea Matthiesen Katja Mertens-Scholz Sven Rinkel Martin Runge Jan Schul Source Type: research

Past and present seroprevalence and disease burden estimates of Toxoplasma gondii infections in Germany: An appreciation of the role of serodiagnostics
Int J Med Microbiol. 2023 Dec 1;313(6):151592. doi: 10.1016/j.ijmm.2023.151592. Online ahead of print.ABSTRACTToxoplasmosis is one of the major foodborne parasitic diseases in Germany, with 49% of its population chronically infected with its causative agent, Toxoplasma gondii. Although the acute disease is usually benign in immunocompetent individuals, it is a threat for immunocompromised patients as well as for fetuses of seronegative mothers. As a result of infection, congenital and ocular toxoplasmosis can have serious lifelong consequences. Here I will highlight the epidemiologic situation, from its past in the two sep...
Source: International Journal of Medical Microbiology - December 6, 2023 Category: Microbiology Authors: Frank Seeber Source Type: research

Interdisciplinary studies on Coxiella burnetii: From molecular to cellular, to host, to one health research
Int J Med Microbiol. 2023 Nov 29;313(6):151590. doi: 10.1016/j.ijmm.2023.151590. Online ahead of print.ABSTRACTThe Q-GAPS (Q fever GermAn interdisciplinary Program for reSearch) consortium was launched in 2017 as a German consortium of more than 20 scientists with exceptional expertise, competence, and substantial knowledge in the field of the Q fever pathogen Coxiella (C.) burnetii. C. burnetii exemplifies as a zoonotic pathogen the challenges of zoonotic disease control and prophylaxis in human, animal, and environmental settings in a One Health approach. An interdisciplinary approach to studying the pathogen is essentia...
Source: International Journal of Medical Microbiology - December 6, 2023 Category: Microbiology Authors: Benjamin U Bauer Michael R Knittler Jennifer Andrack Christian Berens Amely Campe Bahne Christiansen Akinyemi M Fasemore Silke F Fischer Martin Ganter Sophia K örner Gustavo R Makert Svea Matthiesen Katja Mertens-Scholz Sven Rinkel Martin Runge Jan Schul Source Type: research

Past and present seroprevalence and disease burden estimates of Toxoplasma gondii infections in Germany: An appreciation of the role of serodiagnostics
Int J Med Microbiol. 2023 Dec 1;313(6):151592. doi: 10.1016/j.ijmm.2023.151592. Online ahead of print.ABSTRACTToxoplasmosis is one of the major foodborne parasitic diseases in Germany, with 49% of its population chronically infected with its causative agent, Toxoplasma gondii. Although the acute disease is usually benign in immunocompetent individuals, it is a threat for immunocompromised patients as well as for fetuses of seronegative mothers. As a result of infection, congenital and ocular toxoplasmosis can have serious lifelong consequences. Here I will highlight the epidemiologic situation, from its past in the two sep...
Source: International Journal of Medical Microbiology - December 6, 2023 Category: Microbiology Authors: Frank Seeber Source Type: research

Interdisciplinary studies on Coxiella burnetii: From molecular to cellular, to host, to one health research
Int J Med Microbiol. 2023 Nov 29;313(6):151590. doi: 10.1016/j.ijmm.2023.151590. Online ahead of print.ABSTRACTThe Q-GAPS (Q fever GermAn interdisciplinary Program for reSearch) consortium was launched in 2017 as a German consortium of more than 20 scientists with exceptional expertise, competence, and substantial knowledge in the field of the Q fever pathogen Coxiella (C.) burnetii. C. burnetii exemplifies as a zoonotic pathogen the challenges of zoonotic disease control and prophylaxis in human, animal, and environmental settings in a One Health approach. An interdisciplinary approach to studying the pathogen is essentia...
Source: International Journal of Medical Microbiology - December 6, 2023 Category: Microbiology Authors: Benjamin U Bauer Michael R Knittler Jennifer Andrack Christian Berens Amely Campe Bahne Christiansen Akinyemi M Fasemore Silke F Fischer Martin Ganter Sophia K örner Gustavo R Makert Svea Matthiesen Katja Mertens-Scholz Sven Rinkel Martin Runge Jan Schul Source Type: research

Past and present seroprevalence and disease burden estimates of Toxoplasma gondii infections in Germany: An appreciation of the role of serodiagnostics
Int J Med Microbiol. 2023 Dec 1;313(6):151592. doi: 10.1016/j.ijmm.2023.151592. Online ahead of print.ABSTRACTToxoplasmosis is one of the major foodborne parasitic diseases in Germany, with 49% of its population chronically infected with its causative agent, Toxoplasma gondii. Although the acute disease is usually benign in immunocompetent individuals, it is a threat for immunocompromised patients as well as for fetuses of seronegative mothers. As a result of infection, congenital and ocular toxoplasmosis can have serious lifelong consequences. Here I will highlight the epidemiologic situation, from its past in the two sep...
Source: International Journal of Medical Microbiology - December 6, 2023 Category: Microbiology Authors: Frank Seeber Source Type: research